SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5bwd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		4 / 8 GLU A 461
GLU A 404
ASP A 405
ARG A 437
 None
 1.19A 1dtlA-5bwdA:
undetectable		 1dtlA-5bwdA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_A_VIBA502_1
(THIAMIN
PYROPHOSPHOKINASE)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		4 / 8 LEU A 599
ASN A 476
GLN A 609
THR A 481
 PGE  A 905 (-4.7A)
PGE  A 905 (-4.3A)
None
PGE  A 906 (-4.4A)
 1.02A 1ig3A-5bwdA:
undetectable
1ig3B-5bwdA:
undetectable		 1ig3A-5bwdA:
14.22
1ig3B-5bwdA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_A_DVAA6_0
(GRAMICIDIN A)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		3 / 3 ALA A 300
VAL A 260
TRP A 263
 None
 0.80A 1micA-5bwdA:
undetectable
1micB-5bwdA:
undetectable		 1micA-5bwdA:
1.76
1micB-5bwdA:
1.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA141_0
(LYSOZYME C)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		4 / 6 ASP A 724
GLY A 725
THR A 722
PRO A 721
 None
 0.99A 1n4fA-5bwdA:
undetectable		 1n4fA-5bwdA:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		3 / 3 GLU A 132
TRP A 161
LYS A 369
 None
 1.33A 1qu2A-5bwdA:
undetectable		 1qu2A-5bwdA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDN_A_LEUA487_0
(L-AMINO ACID OXIDASE)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		4 / 7 ASN A 490
HIS A 799
ILE A 462
TRP A 792
 None
 1.42A 1tdnA-5bwdA:
undetectable		 1tdnA-5bwdA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XL6_B_SPMB3001_1
(INWARD RECTIFIER
POTASSIUM CHANNEL)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		4 / 5 ALA A 471
TYR A 470
ALA A 485
GLN A 505
 PGE  A 906 ( 4.8A)
None
None
None
 0.98A 1xl6A-5bwdA:
2.4
1xl6B-5bwdA:
undetectable		 1xl6A-5bwdA:
17.35
1xl6B-5bwdA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		4 / 5 ASP A 733
GLY A 706
PRO A 517
ALA A 518
 None
 0.71A 2aofA-5bwdA:
undetectable		 2aofA-5bwdA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOH_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		4 / 5 ASP A 733
GLY A 706
PRO A 517
ALA A 518
 None
 0.75A 2aohA-5bwdA:
undetectable		 2aohA-5bwdA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		4 / 6 THR A 395
ASP A 335
ASN A 408
ASP A 409
 None
None
None
PGE  A 908 ( 4.8A)
 1.23A 2okcA-5bwdA:
undetectable		 2okcA-5bwdA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		4 / 6 TYR A 330
PRO A 202
ILE A 592
LEU A 208
 None
 1.14A 2wekB-5bwdA:
undetectable		 2wekB-5bwdA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		3 / 3 TRP A 488
VAL A 444
ARG A 442
 None
 0.86A 3b0wA-5bwdA:
undetectable		 3b0wA-5bwdA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CD2_A_MTXA307_1
(DIHYDROFOLATE
REDUCTASE)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		5 / 12 ILE A 200
GLU A 324
ILE A 319
PRO A 299
PHE A 315
 None
 1.18A 3cd2A-5bwdA:
undetectable		 3cd2A-5bwdA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E68_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		3 / 3 ARG A  75
ILE A 157
TRP A 161
 None
PG4  A 907 (-4.7A)
None
 1.19A 3e68A-5bwdA:
undetectable		 3e68A-5bwdA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECLA600_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		4 / 8 LEU A 337
THR A 336
GLY A 398
ILE A 498
 None
 0.69A 3jusA-5bwdA:
undetectable		 3jusA-5bwdA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_A_ECNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		4 / 8 LEU A 337
THR A 336
GLY A 398
ILE A 498
 None
 0.69A 3jusA-5bwdA:
undetectable		 3jusA-5bwdA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		5 / 12 ALA A 252
ARG A 325
SER A  86
LEU A  79
ARG A  75
 None
 1.15A 3k2hB-5bwdA:
undetectable		 3k2hB-5bwdA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYE_B_YTZB902_1
(DIHYDROPTEROATE
SYNTHASE)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		3 / 3 PHE A 385
LYS A 377
SER A 378
 None
 0.90A 3tyeB-5bwdA:
2.5		 3tyeB-5bwdA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRM_A_VD3A502_1
(VITAMIN D(3)
25-HYDROXYLASE)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		6 / 12 PRO A 299
LEU A 103
LEU A 318
ILE A 323
ALA A 322
ILE A 592
 None
 1.47A 3vrmA-5bwdA:
undetectable		 3vrmA-5bwdA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		4 / 8 ASP A 594
ASN A 478
GLU A 484
GLU A 598
 None
PGE  A 906 ( 4.9A)
None
None
 1.13A 4feuF-5bwdA:
undetectable		 4feuF-5bwdA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		4 / 7 ASP A 594
ASN A 478
GLU A 484
GLU A 598
 None
PGE  A 906 ( 4.9A)
None
None
 1.11A 4fevD-5bwdA:
undetectable		 4fevD-5bwdA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		4 / 7 ASP A 594
ASN A 478
GLU A 484
GLU A 598
 None
PGE  A 906 ( 4.9A)
None
None
 1.11A 4fevF-5bwdA:
undetectable		 4fevF-5bwdA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		4 / 8 ASP A 594
ASN A 478
GLU A 484
GLU A 598
 None
PGE  A 906 ( 4.9A)
None
None
 1.10A 4fewD-5bwdA:
undetectable		 4fewD-5bwdA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		4 / 8 ASP A 594
ASN A 478
GLU A 484
GLU A 598
 None
PGE  A 906 ( 4.9A)
None
None
 1.11A 4fewF-5bwdA:
undetectable		 4fewF-5bwdA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEX_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		4 / 7 ASP A 594
ASN A 478
GLU A 484
GLU A 598
 None
PGE  A 906 ( 4.9A)
None
None
 1.13A 4fexB-5bwdA:
undetectable		 4fexB-5bwdA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		4 / 5 GLY A 511
GLY A 512
ASN A 615
GLU A 510
 None
FUM  A 901 (-3.5A)
FUM  A 901 (-3.6A)
None
 1.25A 4fglC-5bwdA:
undetectable		 4fglC-5bwdA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		4 / 8 ASP A 594
ASN A 478
GLU A 484
GLU A 598
 None
PGE  A 906 ( 4.9A)
None
None
 1.08A 4gkhB-5bwdA:
undetectable		 4gkhB-5bwdA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		4 / 8 ASP A 594
ASN A 478
GLU A 484
GLU A 598
 None
PGE  A 906 ( 4.9A)
None
None
 1.09A 4gkhF-5bwdA:
undetectable		 4gkhF-5bwdA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		4 / 7 ASP A 594
ASN A 478
GLU A 484
GLU A 598
 None
PGE  A 906 ( 4.9A)
None
None
 1.11A 4gkhG-5bwdA:
undetectable		 4gkhG-5bwdA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		4 / 8 ASP A 594
ASN A 478
GLU A 484
GLU A 598
 None
PGE  A 906 ( 4.9A)
None
None
 1.12A 4gkhC-5bwdA:
undetectable
4gkhK-5bwdA:
undetectable		 4gkhC-5bwdA:
15.08
4gkhK-5bwdA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		4 / 8 ASP A 594
ASN A 478
GLU A 484
GLU A 598
 None
PGE  A 906 ( 4.9A)
None
None
 1.09A 4gkiA-5bwdA:
undetectable		 4gkiA-5bwdA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		4 / 8 ASP A 594
ASN A 478
GLU A 484
GLU A 598
 None
PGE  A 906 ( 4.9A)
None
None
 1.09A 4gkiC-5bwdA:
undetectable		 4gkiC-5bwdA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		4 / 8 ASP A 594
ASN A 478
GLU A 484
GLU A 598
 None
PGE  A 906 ( 4.9A)
None
None
 1.11A 4gkiE-5bwdA:
undetectable
4gkiG-5bwdA:
undetectable		 4gkiE-5bwdA:
15.08
4gkiG-5bwdA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		3 / 3 THR A 618
PRO A 517
THR A 619
 None
 0.84A 4hivD-5bwdA:
undetectable		 4hivD-5bwdA:
2.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_A_DM2A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		5 / 12 GLY A 511
GLY A 512
ASN A 615
GLU A 510
ILE A 570
 None
FUM  A 901 (-3.5A)
FUM  A 901 (-3.6A)
None
None
 1.25A 4zvmA-5bwdA:
undetectable
4zvmB-5bwdA:
undetectable		 4zvmA-5bwdA:
13.21
4zvmB-5bwdA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_B_QELB503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		5 / 11 THR A 316
PRO A 202
ALA A 327
ILE A 200
PRO A 128
 None
 1.49A 5ewjA-5bwdA:
undetectable
5ewjB-5bwdA:
undetectable		 5ewjA-5bwdA:
19.09
5ewjB-5bwdA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_A_ACTA1231_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT
PUTATIVE XANTHINE
DEHYDROGENASE YAGT
IRON-SULFUR-BINDING
SUBUNIT)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		3 / 3 ARG A 437
THR A 411
ASP A 412
 None
 0.71A 5g5gA-5bwdA:
0.6
5g5gB-5bwdA:
undetectable		 5g5gA-5bwdA:
14.14
5g5gB-5bwdA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		3 / 3 TRP A 613
MET A 494
ASN A 490
 FUM  A 901 (-4.5A)
None
None
 1.48A 5uc1B-5bwdA:
undetectable		 5uc1B-5bwdA:
7.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		3 / 3 TRP A 613
MET A 494
ASN A 490
 FUM  A 901 (-4.5A)
None
None
 1.45A 5uc1A-5bwdA:
undetectable		 5uc1A-5bwdA:
7.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC902_0
(MRNA CAPPING ENZYME
P5)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		5 / 12 TYR A 341
GLY A 305
PRO A 302
ASP A 308
GLU A 290
 None
None
None
None
TRS  A 902 ( 4.1A)
 1.30A 5x6yC-5bwdA:
undetectable		 5x6yC-5bwdA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_0
(CYTOCHROME P450 1A1)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		5 / 12 LEU A 318
PHE A 317
GLY A 329
PHE A 392
ASP A 390
 None
 1.25A 6dwnA-5bwdA:
undetectable		 6dwnA-5bwdA:
6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_0
(CYTOCHROME P450 1A1)		 5bwd BENZYLSUCCINATE
SYNTHASE ALPHA CHAIN
(Thauera
aromatica) 		5 / 12 SER A 754
ASN A 862
PHE A 860
ASP A 671
ASP A 857
 None
 1.22A 6dwnA-5bwdA:
undetectable		 6dwnA-5bwdA:
6.99