SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5bwj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWE_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 5bwj SENSORY TRANSDUCTION
HISTIDINE KINASE,
PUTATIVE
(Borreliella
burgdorferi) 		4 / 7 LEU A  97
VAL A  35
TYR A  88
GLY A  90
 None
 1.03A 1lweA-5bwjA:
undetectable		 1lweA-5bwjA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 5bwj SENSORY TRANSDUCTION
HISTIDINE KINASE,
PUTATIVE
(Borreliella
burgdorferi) 		4 / 8 LEU A  97
VAL A  35
TYR A  88
GLY A  90
 None
 1.02A 1s1xA-5bwjA:
undetectable		 1s1xA-5bwjA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_A_CHDA459_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 5bwj SENSORY TRANSDUCTION
HISTIDINE KINASE,
PUTATIVE
(Borreliella
burgdorferi) 		4 / 6 ASP A 195
LEU A 196
VAL A 197
ILE A 198
 None
 0.99A 1s9qA-5bwjA:
undetectable		 1s9qA-5bwjA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_A_ACTA1107_0
(C5A PEPTIDASE)		 5bwj SENSORY TRANSDUCTION
HISTIDINE KINASE,
PUTATIVE
(Borreliella
burgdorferi) 		4 / 5 LEU A  53
GLY A  52
ILE A  54
PHE A  38
 None
 0.96A 1xf1A-5bwjA:
undetectable		 1xf1A-5bwjA:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 5bwj SENSORY TRANSDUCTION
HISTIDINE KINASE,
PUTATIVE
(Borreliella
burgdorferi) 		3 / 3 SER A 214
ALA A 212
VAL A 211
 None
 0.59A 4x1iA-5bwjA:
undetectable		 4x1iA-5bwjA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CFS_A_TOYA203_1
(AAD(2''),GENTAMICIN
2''-NUCLEOTIDYLTRANS
FERASE,GENTAMICIN
RESISTANCE PROTEIN)		 5bwj SENSORY TRANSDUCTION
HISTIDINE KINASE,
PUTATIVE
(Borreliella
burgdorferi) 		4 / 8 TYR A 205
ASP A 202
ILE A 111
TYR A 144
 None
 0.95A 5cfsA-5bwjA:
undetectable		 5cfsA-5bwjA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 5bwj SENSORY TRANSDUCTION
HISTIDINE KINASE,
PUTATIVE
(Borreliella
burgdorferi) 		3 / 3 SER A 214
ALA A 212
VAL A 211
 None
 0.55A 5eypA-5bwjA:
undetectable		 5eypA-5bwjA:
20.79