SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5bwy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 THR A 114
THR A 116
PRO A 113
 None
 0.81A 1a7yA-5bwyA:
undetectable		 1a7yA-5bwyA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 THR A 116
PRO A 113
THR A 114
 None
 0.73A 1a7yB-5bwyA:
undetectable		 1a7yB-5bwyA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 THR A 116
PRO A 113
THR A 114
 None
 0.73A 1dscC-5bwyA:
undetectable		 1dscC-5bwyA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC8_0
(ACTINOMYCIN D)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 THR A 114
THR A 116
PRO A 113
 None
 0.62A 1dscC-5bwyA:
undetectable		 1dscC-5bwyA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 THR A 114
THR A 116
PRO A 113
 None
 0.64A 1fjaC-5bwyA:
undetectable		 1fjaC-5bwyA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 THR A 114
THR A 116
PRO A 113
 None
 0.64A 1fjaD-5bwyA:
undetectable		 1fjaD-5bwyA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 THR A 116
PRO A 113
THR A 114
 None
 0.79A 1i3wE-5bwyA:
undetectable		 1i3wE-5bwyA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 THR A 114
THR A 116
PRO A 113
 None
 0.78A 1i3wE-5bwyA:
undetectable		 1i3wE-5bwyA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 THR A 114
THR A 116
PRO A 113
 None
 0.76A 1i3wF-5bwyA:
undetectable		 1i3wF-5bwyA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 THR A 116
PRO A 113
THR A 114
 None
 0.81A 1i3wG-5bwyA:
undetectable		 1i3wG-5bwyA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 THR A 114
THR A 116
PRO A 113
 None
 0.75A 1i3wG-5bwyA:
undetectable		 1i3wG-5bwyA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 THR A 114
THR A 116
PRO A 113
 None
 0.74A 1i3wH-5bwyA:
undetectable		 1i3wH-5bwyA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_B_CCSB417_0
(ESTROGEN RECEPTOR)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		4 / 6 PRO A  28
PHE A  29
GLN A  26
VAL A  91
 None
 1.21A 1l2iB-5bwyA:
undetectable		 1l2iB-5bwyA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1871_0
(FPRA)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		4 / 7 PHE A 299
ALA A 199
PHE A 259
PHE A 257
 None
 1.15A 1lqtA-5bwyA:
undetectable		 1lqtA-5bwyA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1428_0
(FPRA)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		4 / 7 PHE A 299
ALA A 199
PHE A 259
PHE A 257
 None
 1.14A 1lquA-5bwyA:
undetectable		 1lquA-5bwyA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 THR A 116
PRO A 113
THR A 114
 None
 0.78A 1mnvD-5bwyA:
undetectable		 1mnvD-5bwyA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 THR A 114
THR A 116
PRO A 113
 None
 0.70A 1mnvD-5bwyA:
undetectable		 1mnvD-5bwyA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 THR A 116
PRO A 113
THR A 114
 None
 0.77A 1ovfB-5bwyA:
undetectable		 1ovfB-5bwyA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_D_FUAD705_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		5 / 12 THR A 247
LEU A 227
VAL A 222
PHE A 257
ALA A 219
 None
 1.46A 1q23D-5bwyA:
undetectable
1q23E-5bwyA:
undetectable		 1q23D-5bwyA:
21.98
1q23E-5bwyA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 THR A 114
THR A 116
PRO A 113
 None
 0.80A 1qfiA-5bwyA:
undetectable		 1qfiA-5bwyA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		4 / 7 PHE A 244
VAL A 280
GLY A 281
VAL A 110
 None
 0.90A 1t88A-5bwyA:
undetectable		 1t88A-5bwyA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 THR A 116
PRO A 113
THR A 114
 None
 0.86A 1unjF-5bwyA:
undetectable		 1unjF-5bwyA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 THR A 114
THR A 116
PRO A 113
 None
 0.84A 1unjF-5bwyA:
undetectable		 1unjF-5bwyA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 THR A 116
PRO A 113
THR A 114
 None
 0.75A 1unjL-5bwyA:
undetectable		 1unjL-5bwyA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 THR A 114
THR A 116
PRO A 113
 None
 0.70A 1unjL-5bwyA:
undetectable		 1unjL-5bwyA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 THR A 116
PRO A 113
THR A 114
 None
 0.76A 1unjR-5bwyA:
undetectable		 1unjR-5bwyA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 THR A 114
THR A 116
PRO A 113
 None
 0.72A 1unjR-5bwyA:
undetectable		 1unjR-5bwyA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 THR A 114
THR A 116
PRO A 113
 None
 0.69A 1unjW-5bwyA:
undetectable		 1unjW-5bwyA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 THR A 116
PRO A 113
THR A 114
 None
 0.72A 1unjX-5bwyA:
undetectable		 1unjX-5bwyA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 THR A 114
THR A 116
PRO A 113
 None
 0.74A 1unjX-5bwyA:
undetectable		 1unjX-5bwyA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 THR A 116
PRO A 113
THR A 114
 None
 0.74A 1unmE-5bwyA:
undetectable		 1unmE-5bwyA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 THR A 114
THR A 116
PRO A 113
 None
 0.69A 1unmE-5bwyA:
undetectable		 1unmE-5bwyA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 THR A 116
PRO A 113
THR A 114
 None
 0.73A 1unmF-5bwyA:
undetectable		 1unmF-5bwyA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 THR A 114
THR A 116
PRO A 113
 None
 0.69A 1unmF-5bwyA:
undetectable		 1unmF-5bwyA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 THR A 114
THR A 116
PRO A 113
 None
 0.79A 209dC-5bwyA:
undetectable		 209dC-5bwyA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		4 / 8 PHE A 244
VAL A 280
GLY A 281
VAL A 110
 None
 0.87A 2a1oA-5bwyA:
undetectable		 2a1oA-5bwyA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1122_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		4 / 7 SER A  44
LYS A  46
SER A  87
SER A  60
 None
 1.13A 2j9cA-5bwyA:
undetectable
2j9cB-5bwyA:
undetectable
2j9cC-5bwyA:
undetectable		 2j9cA-5bwyA:
16.71
2j9cB-5bwyA:
16.71
2j9cC-5bwyA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1122_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		4 / 7 SER A  60
SER A  44
LYS A  46
SER A  87
 None
 1.20A 2j9cA-5bwyA:
undetectable
2j9cB-5bwyA:
undetectable
2j9cC-5bwyA:
undetectable		 2j9cA-5bwyA:
16.71
2j9cB-5bwyA:
16.71
2j9cC-5bwyA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1122_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		4 / 7 SER A  87
SER A  60
SER A  44
LYS A  46
 None
 1.19A 2j9cA-5bwyA:
undetectable
2j9cB-5bwyA:
undetectable
2j9cC-5bwyA:
undetectable		 2j9cA-5bwyA:
16.71
2j9cB-5bwyA:
16.71
2j9cC-5bwyA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_1
(PROTEASE)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		5 / 12 LEU A  94
ALA A  89
ASP A  10
ILE A   6
ILE A  93
 None
 1.23A 2o4lA-5bwyA:
6.7		 2o4lA-5bwyA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 THR A 116
PRO A 113
THR A 114
 None
 0.81A 316dC-5bwyA:
undetectable		 316dC-5bwyA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_A_ACTA1002_0
(PUTATIVE
OXIDOREDUCTASE)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		4 / 6 GLY A  23
VAL A  22
ASP A  89
THR A  65
 None
 1.24A 3vqrA-5bwyA:
undetectable		 3vqrA-5bwyA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_B_ACTB1002_0
(PUTATIVE
OXIDOREDUCTASE)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		4 / 5 GLY A  23
VAL A  22
ASP A  89
THR A  65
 None
 1.26A 3vqrB-5bwyA:
undetectable		 3vqrB-5bwyA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 THR A 116
PRO A 113
THR A 114
 None
 0.84A 4hivD-5bwyA:
undetectable		 4hivD-5bwyA:
2.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		4 / 6 TRP A 193
ILE A 195
VAL A 312
ASP A 316
 None
 0.91A 4iaqA-5bwyA:
undetectable		 4iaqA-5bwyA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		4 / 6 TRP A 193
ILE A 195
VAL A 312
SER A 261
 None
 0.96A 4iaqA-5bwyA:
undetectable		 4iaqA-5bwyA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_A_ACTA701_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 5bwy PLASMEPSIN-2
(Plasmodium
falciparum) 		3 / 3 LYS A  46
LYS A  62
SER A  61
 None
 1.32A 5odiA-5bwyA:
undetectable		 5odiA-5bwyA:
20.85