SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5bxg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_D_ADND1504_1
(CLASS B ACID
PHOSPHATASE)		 5bxg UNCHARACTERIZED
BETA-SANDWICH
PROTEIN
(Clostridioides
difficile) 		4 / 8 PHE A 137
ASP A  70
THR A 135
TYR A  80
 None
 0.87A 1rmtD-5bxgA:
undetectable		 1rmtD-5bxgA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_C_ACTC1120_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5bxg UNCHARACTERIZED
BETA-SANDWICH
PROTEIN
(Clostridioides
difficile) 		3 / 3 LYS A  89
TYR A 124
PRO A 160
 None
 1.01A 2j9cC-5bxgA:
undetectable		 2j9cC-5bxgA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_C_ACTC1120_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5bxg UNCHARACTERIZED
BETA-SANDWICH
PROTEIN
(Clostridioides
difficile) 		3 / 3 LYS A 186
TYR A 118
PRO A 169
 None
 1.31A 2j9cC-5bxgA:
undetectable		 2j9cC-5bxgA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA511_1
(PROTON-GATED ION
CHANNEL)		 5bxg UNCHARACTERIZED
BETA-SANDWICH
PROTEIN
(Clostridioides
difficile) 		4 / 8 ILE A 114
ILE A  60
ALA A  96
ILE A  62
 None
 0.73A 5mvmA-5bxgA:
undetectable
5mvmB-5bxgA:
undetectable		 5mvmA-5bxgA:
20.37
5mvmB-5bxgA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 5bxg UNCHARACTERIZED
BETA-SANDWICH
PROTEIN
(Clostridioides
difficile) 		3 / 3 ASP A  70
PHE A 137
ARG A 154
 None
None
EDO  A 203 (-3.7A)
 1.10A 5yw0A-5bxgA:
undetectable		 5yw0A-5bxgA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))		 5bxg UNCHARACTERIZED
BETA-SANDWICH
PROTEIN
(Clostridioides
difficile) 		3 / 3 TYR A  83
PRO A  73
LEU A  72
 None
 0.85A 6beoA-5bxgA:
undetectable		 6beoA-5bxgA:
8.00