SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5byk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		5 / 9 THR A  20
SER A  12
HIS A  37
ALA A  88
THR A  94
 A3P  A 301 (-2.8A)
None
OAQ  A 302 ( 4.6A)
None
None
 1.38A 1c9sF-5bykA:
undetectable
1c9sG-5bykA:
undetectable		 1c9sF-5bykA:
21.92
1c9sG-5bykA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTX_A_CVIA200_0
(HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR IN QACA
5'REGION)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		5 / 12 THR A  89
TYR A  36
ILE A  41
ILE A  42
ALA A 164
 None
 1.20A 1jtxA-5bykA:
undetectable		 1jtxA-5bykA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		5 / 10 ILE A   8
LEU A 111
LYS A 109
ILE A  30
ILE A  87
 None
 1.28A 1rb3A-5bykA:
undetectable		 1rb3A-5bykA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RE7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		5 / 12 ILE A   8
LEU A 111
LYS A 109
ILE A  30
ILE A  87
 None
 1.12A 1re7A-5bykA:
undetectable		 1re7A-5bykA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_A_HSMA401_1
(NITROPHORIN 1)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		4 / 4 ASP A 175
LEU A 124
LEU A 129
LEU A 121
 None
 1.38A 1u18A-5bykA:
undetectable		 1u18A-5bykA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_K_TRPK81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		5 / 9 THR A  20
SER A  12
HIS A  37
ALA A  88
THR A  94
 A3P  A 301 (-2.8A)
None
OAQ  A 302 ( 4.6A)
None
None
 1.40A 1utdA-5bykA:
undetectable
1utdK-5bykA:
undetectable		 1utdA-5bykA:
21.92
1utdK-5bykA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_D_H4BD1290_1
(PTERIDINE REDUCTASE
1)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		4 / 8 LEU A 149
TYR A 154
LEU A 240
LEU A 236
 None
 0.98A 2bfpD-5bykA:
undetectable		 2bfpD-5bykA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN3_A_ID8A1356_1
(THYROXINE-BINDING
GLOBULIN)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		4 / 8 GLN A  46
LEU A 156
LYS A 155
LEU A 149
 None
 1.11A 2xn3A-5bykA:
undetectable
2xn3B-5bykA:
undetectable		 2xn3A-5bykA:
21.78
2xn3B-5bykA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		4 / 7 ILE A  42
PHE A  39
MET A 233
THR A 234
 None
 1.03A 3ag2N-5bykA:
undetectable
3ag2W-5bykA:
undetectable		 3ag2N-5bykA:
18.80
3ag2W-5bykA:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		4 / 7 ILE A  42
PHE A  39
MET A 233
THR A 234
 None
 1.04A 3ag4N-5bykA:
undetectable
3ag4W-5bykA:
undetectable		 3ag4N-5bykA:
18.80
3ag4W-5bykA:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		5 / 12 GLY A  96
LEU A 156
MET A  38
LEU A  83
LEU A  79
 None
None
OAQ  A 302 (-4.3A)
None
None
 1.04A 3cs8A-5bykA:
undetectable		 3cs8A-5bykA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_A_J3ZA2_1
(ESTROGEN RECEPTOR)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		5 / 12 MET A 233
LEU A 236
THR A 237
LEU A 149
LEU A 246
 None
None
OAQ  A 302 (-3.8A)
None
None
 1.15A 3hm1A-5bykA:
undetectable		 3hm1A-5bykA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_B_VK3B202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		4 / 6 TRP A  52
TYR A  36
TYR A  86
LEU A  83
 None
 1.38A 4f8yA-5bykA:
undetectable
4f8yB-5bykA:
undetectable		 4f8yA-5bykA:
22.10
4f8yB-5bykA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		4 / 7 TYR A  36
TYR A  86
LEU A  83
TRP A  52
 None
 1.33A 4f8yC-5bykA:
undetectable
4f8yD-5bykA:
undetectable		 4f8yC-5bykA:
22.10
4f8yD-5bykA:
22.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		5 / 12 HIS A  37
PHE A  39
VAL A 127
GLY A 143
ASP A 144
 OAQ  A 302 ( 4.6A)
None
OAQ  A 302 (-4.9A)
OAQ  A 302 ( 4.1A)
OAQ  A 302 (-3.3A)
 1.12A 4mubA-5bykA:
44.7		 4mubA-5bykA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		12 / 12 PRO A  16
HIS A  37
MET A  38
PHE A  39
LEU A  92
VAL A 128
GLY A 143
ASP A 144
PHE A 153
THR A 157
MET A 233
THR A 237
 OAQ  A 302 (-4.4A)
OAQ  A 302 ( 4.6A)
OAQ  A 302 (-4.3A)
None
OAQ  A 302 (-4.0A)
OAQ  A 302 (-4.0A)
OAQ  A 302 ( 4.1A)
OAQ  A 302 (-3.3A)
OAQ  A 302 ( 4.8A)
OAQ  A 302 (-2.6A)
None
OAQ  A 302 (-3.8A)
 0.19A 4mubA-5bykA:
44.7		 4mubA-5bykA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		6 / 12 PRO A  16
HIS A  37
PHE A  39
LEU A  92
VAL A 128
THR A 234
 OAQ  A 302 (-4.4A)
OAQ  A 302 ( 4.6A)
None
OAQ  A 302 (-4.0A)
OAQ  A 302 (-4.0A)
None
 1.22A 4mubA-5bykA:
44.7		 4mubA-5bykA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_K_IPHK101_0
(INSULIN)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		6 / 12 VAL A  10
LEU A 214
ILE A  87
CYH A  35
LEU A  23
ALA A  26
 None
 1.48A 4p65F-5bykA:
undetectable
4p65H-5bykA:
undetectable
4p65K-5bykA:
undetectable
4p65L-5bykA:
undetectable		 4p65F-5bykA:
8.37
4p65H-5bykA:
8.37
4p65K-5bykA:
5.99
4p65L-5bykA:
8.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_B_MN9B401_0
(N-ACETYLNEURAMINATE
LYASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		4 / 6 SER A 245
LEU A 246
ASP A 247
LEU A 240
 None
 1.01A 4wozA-5bykA:
undetectable
4wozB-5bykA:
undetectable		 4wozA-5bykA:
24.84
4wozB-5bykA:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZPH_A_PRLA501_0
(ARYL HYDROCARBON
RECEPTOR NUCLEAR
TRANSLOCATOR
ENDOTHELIAL PAS
DOMAIN-CONTAINING
PROTEIN 1)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		4 / 7 VAL A 200
GLN A 190
LEU A 198
SER A 195
 None
 1.05A 4zphA-5bykA:
undetectable
4zphB-5bykA:
undetectable		 4zphA-5bykA:
19.44
4zphB-5bykA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_A_SAMA301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		5 / 12 GLY A 206
GLY A 204
THR A 113
ILE A 218
LEU A  23
 None
A3P  A 301 ( 4.3A)
None
None
None
 1.01A 5bw4A-5bykA:
undetectable		 5bw4A-5bykA:
21.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		12 / 12 HIS A  37
MET A  38
PHE A  39
ILE A  42
LEU A  92
VAL A 128
GLY A 143
PHE A 153
THR A 157
MET A 233
LEU A 236
THR A 237
 OAQ  A 302 ( 4.6A)
OAQ  A 302 (-4.3A)
None
None
OAQ  A 302 (-4.0A)
OAQ  A 302 (-4.0A)
OAQ  A 302 ( 4.1A)
OAQ  A 302 ( 4.8A)
OAQ  A 302 (-2.6A)
None
None
OAQ  A 302 (-3.8A)
 0.32A 5byjA-5bykA:
44.6		 5byjA-5bykA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		6 / 12 PRO A  16
HIS A  37
LEU A  92
VAL A 127
VAL A 128
THR A 234
 OAQ  A 302 (-4.4A)
OAQ  A 302 ( 4.6A)
OAQ  A 302 (-4.0A)
OAQ  A 302 (-4.9A)
OAQ  A 302 (-4.0A)
None
 1.37A 5bykA-5bykA:
46.1		 5bykA-5bykA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		12 / 12 PRO A  16
HIS A  37
MET A  38
ILE A  42
LEU A  92
VAL A 127
VAL A 128
LEU A 147
PHE A 153
THR A 157
MET A 233
THR A 237
 OAQ  A 302 (-4.4A)
OAQ  A 302 ( 4.6A)
OAQ  A 302 (-4.3A)
None
OAQ  A 302 (-4.0A)
OAQ  A 302 (-4.9A)
OAQ  A 302 (-4.0A)
None
OAQ  A 302 ( 4.8A)
OAQ  A 302 (-2.6A)
None
OAQ  A 302 (-3.8A)
 0.22A 5bykA-5bykA:
46.1		 5bykA-5bykA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		5 / 10 THR A  20
SER A  12
HIS A  37
ALA A  88
THR A  94
 A3P  A 301 (-2.8A)
None
OAQ  A 302 ( 4.6A)
None
None
 1.42A 5eeuD-5bykA:
undetectable
5eeuE-5bykA:
undetectable		 5eeuD-5bykA:
21.92
5eeuE-5bykA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		5 / 10 THR A  20
SER A  12
HIS A  37
ALA A  88
THR A  94
 A3P  A 301 (-2.8A)
None
OAQ  A 302 ( 4.6A)
None
None
 1.42A 5eevD-5bykA:
undetectable
5eevE-5bykA:
undetectable		 5eevD-5bykA:
21.92
5eevE-5bykA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		5 / 10 THR A  20
SER A  12
HIS A  37
ALA A  88
THR A  94
 A3P  A 301 (-2.8A)
None
OAQ  A 302 ( 4.6A)
None
None
 1.42A 5eewD-5bykA:
undetectable
5eewE-5bykA:
undetectable		 5eewD-5bykA:
21.92
5eewE-5bykA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		5 / 10 THR A  20
SER A  12
HIS A  37
ALA A  88
THR A  94
 A3P  A 301 (-2.8A)
None
OAQ  A 302 ( 4.6A)
None
None
 1.41A 5eeyD-5bykA:
undetectable
5eeyE-5bykA:
undetectable		 5eeyD-5bykA:
21.92
5eeyE-5bykA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		5 / 10 THR A  20
SER A  12
HIS A  37
ALA A  88
THR A  94
 A3P  A 301 (-2.8A)
None
OAQ  A 302 ( 4.6A)
None
None
 1.41A 5ef0D-5bykA:
undetectable
5ef0E-5bykA:
undetectable		 5ef0D-5bykA:
21.92
5ef0E-5bykA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		5 / 10 THR A  20
SER A  12
HIS A  37
ALA A  88
THR A  94
 A3P  A 301 (-2.8A)
None
OAQ  A 302 ( 4.6A)
None
None
 1.41A 5ef1D-5bykA:
undetectable
5ef1E-5bykA:
undetectable		 5ef1D-5bykA:
21.92
5ef1E-5bykA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		3 / 3 LYS A 126
HIS A 122
HIS A 230
 None
None
A3P  A 301 (-4.2A)
 1.16A 5oexA-5bykA:
undetectable		 5oexA-5bykA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		3 / 3 LYS A 126
HIS A 122
HIS A 230
 None
None
A3P  A 301 (-4.2A)
 1.20A 5oexB-5bykA:
undetectable		 5oexB-5bykA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		3 / 3 LYS A 126
HIS A 122
HIS A 230
 None
None
A3P  A 301 (-4.2A)
 1.16A 5oexC-5bykA:
undetectable		 5oexC-5bykA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		3 / 3 LYS A 126
HIS A 122
HIS A 230
 None
None
A3P  A 301 (-4.2A)
 1.13A 5oexD-5bykA:
undetectable		 5oexD-5bykA:
20.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		12 / 12 PRO A  16
MET A  38
ILE A  42
LEU A  92
VAL A 127
VAL A 128
ILE A 140
LEU A 147
PHE A 153
LEU A 236
THR A 237
LEU A 240
 OAQ  A 302 (-4.4A)
OAQ  A 302 (-4.3A)
None
OAQ  A 302 (-4.0A)
OAQ  A 302 (-4.9A)
OAQ  A 302 (-4.0A)
None
None
OAQ  A 302 ( 4.8A)
None
OAQ  A 302 (-3.8A)
None
 0.27A 5tiwA-5bykA:
39.8		 5tiwA-5bykA:
75.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		11 / 12 PRO A  16
MET A  38
ILE A  42
ASP A  91
LEU A  92
VAL A 128
ILE A 140
ASP A 144
PHE A 153
LEU A 236
THR A 237
 OAQ  A 302 (-4.4A)
OAQ  A 302 (-4.3A)
None
OAQ  A 302 (-2.7A)
OAQ  A 302 (-4.0A)
OAQ  A 302 (-4.0A)
None
OAQ  A 302 (-3.3A)
OAQ  A 302 ( 4.8A)
None
OAQ  A 302 (-3.8A)
 0.41A 5tiwB-5bykA:
39.2		 5tiwB-5bykA:
75.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TIX_A_OQRA302_0
(SULFOTRANSFERASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		8 / 9 PRO A  16
MET A  38
LEU A  92
VAL A 128
LEU A 129
ILE A 140
ASP A 144
PHE A 153
 OAQ  A 302 (-4.4A)
OAQ  A 302 (-4.3A)
OAQ  A 302 (-4.0A)
OAQ  A 302 (-4.0A)
None
None
OAQ  A 302 (-3.3A)
OAQ  A 302 ( 4.8A)
 0.39A 5tixA-5bykA:
39.8		 5tixA-5bykA:
75.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		9 / 10 PRO A  16
MET A  38
ILE A  42
LEU A  92
VAL A 128
LEU A 129
ASP A 144
PHE A 153
GLU A 158
 OAQ  A 302 (-4.4A)
OAQ  A 302 (-4.3A)
None
OAQ  A 302 (-4.0A)
OAQ  A 302 (-4.0A)
None
OAQ  A 302 (-3.3A)
OAQ  A 302 ( 4.8A)
None
 0.55A 5tixB-5bykA:
39.6		 5tixB-5bykA:
75.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TIY_A_OAQA302_0
(SULFOTRANSFERASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		10 / 11 PRO A  16
MET A  38
ILE A  42
ASP A  91
VAL A 128
ASP A 144
PHE A 153
MET A 233
LEU A 236
THR A 237
 OAQ  A 302 (-4.4A)
OAQ  A 302 (-4.3A)
None
OAQ  A 302 (-2.7A)
OAQ  A 302 (-4.0A)
OAQ  A 302 (-3.3A)
OAQ  A 302 ( 4.8A)
None
None
OAQ  A 302 (-3.8A)
 0.38A 5tiyA-5bykA:
39.7		 5tiyA-5bykA:
75.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B4Y_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		10 / 10 MET A  38
ILE A  42
ASP A  91
LEU A  92
VAL A 128
ASP A 144
PHE A 153
THR A 157
MET A 233
THR A 237
 OAQ  A 302 (-4.3A)
None
OAQ  A 302 (-2.7A)
OAQ  A 302 (-4.0A)
OAQ  A 302 (-4.0A)
OAQ  A 302 (-3.3A)
OAQ  A 302 ( 4.8A)
OAQ  A 302 (-2.6A)
None
OAQ  A 302 (-3.8A)
 0.33A 6b4yA-5bykA:
43.3		 6b4yA-5bykA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		7 / 12 PRO A  16
HIS A  37
ASP A  91
LEU A  92
VAL A 127
VAL A 128
THR A 234
 OAQ  A 302 (-4.4A)
OAQ  A 302 ( 4.6A)
OAQ  A 302 (-2.7A)
OAQ  A 302 (-4.0A)
OAQ  A 302 (-4.9A)
OAQ  A 302 (-4.0A)
None
 1.32A 6b50A-5bykA:
44.2		 6b50A-5bykA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		6 / 12 PRO A  16
HIS A  37
MET A  38
ASP A  91
LEU A  92
SER A 160
 OAQ  A 302 (-4.4A)
OAQ  A 302 ( 4.6A)
OAQ  A 302 (-4.3A)
OAQ  A 302 (-2.7A)
OAQ  A 302 (-4.0A)
None
 1.49A 6b50A-5bykA:
44.2		 6b50A-5bykA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		11 / 12 PRO A  16
HIS A  37
MET A  38
ASP A  91
LEU A  92
VAL A 127
VAL A 128
ASP A 144
PHE A 153
MET A 233
THR A 237
 OAQ  A 302 (-4.4A)
OAQ  A 302 ( 4.6A)
OAQ  A 302 (-4.3A)
OAQ  A 302 (-2.7A)
OAQ  A 302 (-4.0A)
OAQ  A 302 (-4.9A)
OAQ  A 302 (-4.0A)
OAQ  A 302 (-3.3A)
OAQ  A 302 ( 4.8A)
None
OAQ  A 302 (-3.8A)
 0.26A 6b50A-5bykA:
44.2		 6b50A-5bykA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		11 / 12 PRO A  16
MET A  38
ILE A  42
LEU A  92
VAL A 127
VAL A 128
LEU A 147
PHE A 153
MET A 233
LEU A 236
THR A 237
 OAQ  A 302 (-4.4A)
OAQ  A 302 (-4.3A)
None
OAQ  A 302 (-4.0A)
OAQ  A 302 (-4.9A)
OAQ  A 302 (-4.0A)
None
OAQ  A 302 ( 4.8A)
None
None
OAQ  A 302 (-3.8A)
 0.37A 6b52A-5bykA:
39.8		 6b52A-5bykA:
75.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		12 / 12 MET A  38
ILE A  42
ASP A  91
LEU A  92
VAL A 128
ASP A 144
LEU A 147
PHE A 153
THR A 157
MET A 233
THR A 237
LEU A 240
 OAQ  A 302 (-4.3A)
None
OAQ  A 302 (-2.7A)
OAQ  A 302 (-4.0A)
OAQ  A 302 (-4.0A)
OAQ  A 302 (-3.3A)
None
OAQ  A 302 ( 4.8A)
OAQ  A 302 (-2.6A)
None
OAQ  A 302 (-3.8A)
None
 0.46A 6b54A-5bykA:
39.3		 6b54A-5bykA:
75.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		4 / 6 PHE A 165
LEU A 161
ALA A 164
THR A  18
 None
 1.00A 6f88A-5bykA:
undetectable		 6f88A-5bykA:
12.40