SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5byp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOS_A_VIAA1_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 5byp PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		5 / 12 TYR A  40
PHE A 147
MET A 136
PHE A 126
ILE A  89
 None
 1.40A 1xosA-5bypA:
undetectable		 1xosA-5bypA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA502_1
(CYTOCHROME P450 2C8)		 5byp PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		5 / 12 ILE A  87
SER A  88
ILE A  89
LEU A 138
ASN A 139
 None
 1.01A 2nnhA-5bypA:
undetectable		 2nnhA-5bypA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFG_B_LEUB289_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 5byp PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		3 / 3 PHE A  76
SER A 109
SER A 111
 None
 0.83A 3ufgB-5bypA:
undetectable		 3ufgB-5bypA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_I_BEZI1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 5byp PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		3 / 3 SER A  61
TYR A  79
TYR A  80
 None
 0.68A 5lakA-5bypA:
undetectable
5lakI-5bypA:
undetectable		 5lakA-5bypA:
16.14
5lakI-5bypA:
2.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_J_BEZJ1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 5byp PUTATIVE
UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		3 / 3 SER A  61
TYR A  79
TYR A  80
 None
 0.71A 5lakC-5bypA:
undetectable
5lakJ-5bypA:
undetectable		 5lakC-5bypA:
16.14
5lakJ-5bypA:
2.56