SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5c04'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 5c04 PUTATIVE
PEROXIREDOXIN MT2298
(Mycobacterium
tuberculosis) 		4 / 8 PRO A  38
THR A  42
CYH A  45
ARG A 116
 None
 0.51A 1h4oB-5c04A:
19.5		 1h4oB-5c04A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 5c04 PUTATIVE
PEROXIREDOXIN MT2298
(Mycobacterium
tuberculosis) 		4 / 8 PRO A  38
THR A  42
CYH A  45
ARG A 116
 None
 0.50A 1h4oG-5c04A:
19.4		 1h4oG-5c04A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 5c04 PUTATIVE
PEROXIREDOXIN MT2298
(Mycobacterium
tuberculosis) 		4 / 8 PRO A  38
THR A  42
CYH A  45
ARG A 116
 None
 0.50A 1oc3A-5c04A:
19.5		 1oc3A-5c04A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)		 5c04 PUTATIVE
PEROXIREDOXIN MT2298
(Mycobacterium
tuberculosis) 		4 / 4 VAL A  35
ALA A  66
LEU A  56
PHE A  88
 None
 1.06A 1q97B-5c04A:
undetectable		 1q97B-5c04A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)		 5c04 PUTATIVE
PEROXIREDOXIN MT2298
(Mycobacterium
tuberculosis) 		4 / 4 VAL A  35
ALA A  66
LEU A 148
PHE A  59
 None
 1.19A 1q97B-5c04A:
undetectable		 1q97B-5c04A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 5c04 PUTATIVE
PEROXIREDOXIN MT2298
(Mycobacterium
tuberculosis) 		4 / 5 GLY A 105
PRO A   9
ALA A   8
ILE A 127
 None
 0.92A 2aofA-5c04A:
undetectable		 2aofA-5c04A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_1
(PROTEASE RETROPEPSIN)		 5c04 PUTATIVE
PEROXIREDOXIN MT2298
(Mycobacterium
tuberculosis) 		5 / 12 ALA A 130
GLY A 105
PRO A   9
ALA A   8
ILE A 127
 None
 0.87A 2rkfA-5c04A:
undetectable		 2rkfA-5c04A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_2
(PROTEASE)		 5c04 PUTATIVE
PEROXIREDOXIN MT2298
(Mycobacterium
tuberculosis) 		5 / 9 ALA A 130
GLY A 105
PRO A   9
ALA A   8
ILE A 127
 None
 0.95A 3ektB-5c04A:
undetectable		 3ektB-5c04A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_1
(PROTEASE)		 5c04 PUTATIVE
PEROXIREDOXIN MT2298
(Mycobacterium
tuberculosis) 		5 / 10 ALA A 130
GLY A 105
PRO A   9
ALA A   8
ILE A 127
 None
 0.95A 3ekwA-5c04A:
undetectable		 3ekwA-5c04A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB501_1
(HEMOLYTIC LECTIN
CEL-III)		 5c04 PUTATIVE
PEROXIREDOXIN MT2298
(Mycobacterium
tuberculosis) 		4 / 5 ASP A  50
SER A  84
GLY A  85
ASP A  54
 None
 1.18A 3w9tB-5c04A:
undetectable		 3w9tB-5c04A:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1003_1
(HEMOLYTIC LECTIN
CEL-III)		 5c04 PUTATIVE
PEROXIREDOXIN MT2298
(Mycobacterium
tuberculosis) 		4 / 5 ASP A  50
SER A  84
GLY A  85
ASP A  54
 None
 1.19A 3w9tC-5c04A:
undetectable		 3w9tC-5c04A:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD501_1
(HEMOLYTIC LECTIN
CEL-III)		 5c04 PUTATIVE
PEROXIREDOXIN MT2298
(Mycobacterium
tuberculosis) 		4 / 5 ASP A  50
SER A  84
GLY A  85
ASP A  54
 None
 1.20A 3w9tD-5c04A:
undetectable		 3w9tD-5c04A:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP9_C_1WEC706_1
(TRANSPORTER)		 5c04 PUTATIVE
PEROXIREDOXIN MT2298
(Mycobacterium
tuberculosis) 		4 / 4 PHE A 107
ASP A  93
GLY A 112
SER A 101
 None
 1.40A 4xp9C-5c04A:
undetectable		 4xp9C-5c04A:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4N_C_ACTC201_0
(NITROGEN REGULATORY
PROTEIN P-II)		 5c04 PUTATIVE
PEROXIREDOXIN MT2298
(Mycobacterium
tuberculosis) 		4 / 5 VAL A 100
VAL A 106
GLY A 105
PHE A  36
 None
 1.11A 5d4nA-5c04A:
undetectable
5d4nC-5c04A:
undetectable		 5d4nA-5c04A:
25.00
5d4nC-5c04A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_C_RAPC999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 5c04 PUTATIVE
PEROXIREDOXIN MT2298
(Mycobacterium
tuberculosis) 		4 / 8 GLU A 131
GLY A 105
THR A   7
PHE A 129
 None
 0.94A 5flcB-5c04A:
undetectable		 5flcB-5c04A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_G_RAPG999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 5c04 PUTATIVE
PEROXIREDOXIN MT2298
(Mycobacterium
tuberculosis) 		4 / 8 GLU A 131
GLY A 105
THR A   7
PHE A 129
 None
 0.94A 5flcF-5c04A:
undetectable		 5flcF-5c04A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_B_REAB601_1
(RETINOIC ACID
RECEPTOR)		 5c04 PUTATIVE
PEROXIREDOXIN MT2298
(Mycobacterium
tuberculosis) 		5 / 10 LEU A  90
PHE A  88
GLY A  47
GLY A 117
ARG A 116
 None
 1.20A 6eu9B-5c04A:
undetectable		 6eu9B-5c04A:
20.69