SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5c05'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)		 5c05 PUTATIVE
GAMMA-TERPINENE
SYNTHASE
(Thymus
vulgaris) 		4 / 7 ILE A 204
ARG A 161
PHE A 157
PHE A 183
 ILE  A 204 ( 0.7A)
ARG  A 161 (-0.6A)
PHE  A 157 ( 1.3A)
PHE  A 183 ( 1.3A)
 1.09A 1e71M-5c05A:
undetectable		 1e71M-5c05A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 5c05 PUTATIVE
GAMMA-TERPINENE
SYNTHASE
(Thymus
vulgaris) 		4 / 7 ILE A 204
ARG A 161
PHE A 157
PHE A 183
 ILE  A 204 ( 0.7A)
ARG  A 161 (-0.6A)
PHE  A 157 ( 1.3A)
PHE  A 183 ( 1.3A)
 1.12A 1e72M-5c05A:
undetectable		 1e72M-5c05A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E73_M_ASCM995_0
(MYROSINASE MA1)		 5c05 PUTATIVE
GAMMA-TERPINENE
SYNTHASE
(Thymus
vulgaris) 		4 / 6 ILE A 204
ARG A 161
PHE A 157
PHE A 183
 ILE  A 204 ( 0.7A)
ARG  A 161 (-0.6A)
PHE  A 157 ( 1.3A)
PHE  A 183 ( 1.3A)
 1.07A 1e73M-5c05A:
undetectable		 1e73M-5c05A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3002_1
(SERUM ALBUMIN)		 5c05 PUTATIVE
GAMMA-TERPINENE
SYNTHASE
(Thymus
vulgaris) 		4 / 8 LEU A 562
LEU A 482
TYR A 478
SER A 416
 LEU  A 562 ( 0.6A)
LEU  A 482 ( 0.5A)
TYR  A 478 ( 1.3A)
SER  A 416 ( 0.0A)
 1.20A 1hk2A-5c05A:
2.2		 1hk2A-5c05A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_C_AG2C7004_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 5c05 PUTATIVE
GAMMA-TERPINENE
SYNTHASE
(Thymus
vulgaris) 		4 / 6 LEU A 195
GLU A 223
LEU A 243
LEU A 236
 LEU  A 195 ( 0.6A)
GLU  A 223 ( 0.5A)
LEU  A 243 ( 0.5A)
LEU  A 236 ( 0.6A)
 1.00A 1mt1D-5c05A:
undetectable
1mt1E-5c05A:
undetectable		 1mt1D-5c05A:
11.27
1mt1E-5c05A:
6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 5c05 PUTATIVE
GAMMA-TERPINENE
SYNTHASE
(Thymus
vulgaris) 		3 / 3 GLU A 427
ASN A 445
TRP A 430
 GLU  A 427 ( 0.6A)
ASN  A 445 ( 0.6A)
TRP  A 430 ( 0.5A)
 1.19A 1r15D-5c05A:
undetectable		 1r15D-5c05A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 5c05 PUTATIVE
GAMMA-TERPINENE
SYNTHASE
(Thymus
vulgaris) 		3 / 3 GLU A 427
ASN A 445
TRP A 430
 GLU  A 427 ( 0.6A)
ASN  A 445 ( 0.6A)
TRP  A 430 ( 0.5A)
 1.16A 1r15F-5c05A:
undetectable		 1r15F-5c05A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_B_SAMB1400_0
(UPF0088 PROTEIN
AQ_165)		 5c05 PUTATIVE
GAMMA-TERPINENE
SYNTHASE
(Thymus
vulgaris) 		5 / 12 VAL A 147
GLY A 148
LEU A 155
THR A 153
ALA A 156
 VAL  A 147 ( 0.6A)
GLY  A 148 ( 0.0A)
LEU  A 155 ( 0.6A)
THR  A 153 ( 0.8A)
ALA  A 156 ( 0.0A)
 1.00A 2egvB-5c05A:
undetectable		 2egvB-5c05A:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 5c05 PUTATIVE
GAMMA-TERPINENE
SYNTHASE
(Thymus
vulgaris) 		5 / 12 ALA A 543
ASN A 541
VAL A 206
ASN A 480
ARG A 564
 ALA  A 543 ( 0.0A)
ASN  A 541 (-0.6A)
VAL  A 206 ( 0.6A)
ASN  A 480 ( 0.6A)
ARG  A 564 ( 0.6A)
 1.12A 2okcB-5c05A:
undetectable		 2okcB-5c05A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_NCAA493_0
(CHORISMATE SYNTHASE)		 5c05 PUTATIVE
GAMMA-TERPINENE
SYNTHASE
(Thymus
vulgaris) 		5 / 11 ARG A 564
ILE A 481
ILE A 488
ALA A 559
VAL A 556
 ARG  A 564 ( 0.6A)
ILE  A 481 ( 0.7A)
ILE  A 488 ( 0.7A)
ALA  A 559 ( 0.0A)
VAL  A 556 ( 0.6A)
 1.18A 2qhfA-5c05A:
undetectable		 2qhfA-5c05A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_D_BEZD1221_0
(PEROXIREDOXIN 6)		 5c05 PUTATIVE
GAMMA-TERPINENE
SYNTHASE
(Thymus
vulgaris) 		4 / 8 VAL A 448
THR A 454
PRO A 453
SER A 457
 VAL  A 448 ( 0.5A)
THR  A 454 ( 0.8A)
PRO  A 453 ( 1.1A)
SER  A 457 ( 0.0A)
 0.95A 2v32C-5c05A:
undetectable
2v32D-5c05A:
undetectable		 2v32C-5c05A:
17.32
2v32D-5c05A:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI9_X_SAMX501_0
(UPF0217 PROTEIN
MJ1640)		 5c05 PUTATIVE
GAMMA-TERPINENE
SYNTHASE
(Thymus
vulgaris) 		5 / 9 ILE A 450
GLY A 486
SER A 419
LEU A 420
SER A 416
 ILE  A 450 ( 0.4A)
GLY  A 486 ( 0.0A)
SER  A 419 ( 0.0A)
LEU  A 420 ( 0.6A)
SER  A 416 ( 0.0A)
 1.00A 3ai9X-5c05A:
undetectable		 3ai9X-5c05A:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA402_1
(HIV-1 PROTEASE)		 5c05 PUTATIVE
GAMMA-TERPINENE
SYNTHASE
(Thymus
vulgaris) 		4 / 5 ARG A 490
LEU A 443
PRO A 437
ASP A 494
 ARG  A 490 ( 0.6A)
LEU  A 443 ( 0.6A)
PRO  A 437 ( 1.1A)
ASP  A 494 ( 0.6A)
 1.07A 3ufnA-5c05A:
undetectable
3ufnB-5c05A:
undetectable		 3ufnA-5c05A:
10.81
3ufnB-5c05A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZS3_A_ACTA1224_0
(THAUMATIN-LIKE
PROTEIN)		 5c05 PUTATIVE
GAMMA-TERPINENE
SYNTHASE
(Thymus
vulgaris) 		4 / 5 SER A 377
GLU A 374
THR A 378
ASP A 372
 SER  A 377 ( 0.0A)
GLU  A 374 ( 0.6A)
THR  A 378 ( 0.8A)
ASP  A 372 ( 0.6A)
 1.49A 3zs3A-5c05A:
undetectable		 3zs3A-5c05A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTR_A_IBPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 5c05 PUTATIVE
GAMMA-TERPINENE
SYNTHASE
(Thymus
vulgaris) 		4 / 8 VAL A 345
TRP A 321
LEU A 325
LEU A 562
 VAL  A 345 ( 0.6A)
TRP  A 321 ( 0.5A)
LEU  A 325 ( 0.5A)
LEU  A 562 ( 0.6A)
 0.66A 4jtrA-5c05A:
undetectable		 4jtrA-5c05A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA604_1
(TRANSPORTER)		 5c05 PUTATIVE
GAMMA-TERPINENE
SYNTHASE
(Thymus
vulgaris) 		4 / 7 ILE A  92
PHE A 124
LEU A 276
ASP A 280
 ILE  A  92 ( 0.6A)
PHE  A 124 ( 1.3A)
LEU  A 276 ( 0.6A)
ASP  A 280 ( 0.5A)
 0.82A 4mmcA-5c05A:
undetectable		 4mmcA-5c05A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_A_BQ1A1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 5c05 PUTATIVE
GAMMA-TERPINENE
SYNTHASE
(Thymus
vulgaris) 		3 / 3 GLU A 255
ALA A 256
PHE A 259
 GLU  A 255 ( 0.5A)
ALA  A 256 ( 0.0A)
PHE  A 259 (-1.3A)
 0.54A 4v1fA-5c05A:
undetectable		 4v1fA-5c05A:
9.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_C_BQ1C1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 5c05 PUTATIVE
GAMMA-TERPINENE
SYNTHASE
(Thymus
vulgaris) 		3 / 3 GLU A 255
ALA A 256
PHE A 259
 GLU  A 255 ( 0.5A)
ALA  A 256 ( 0.0A)
PHE  A 259 (-1.3A)
 0.58A 4v1fC-5c05A:
undetectable		 4v1fC-5c05A:
9.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5c05 PUTATIVE
GAMMA-TERPINENE
SYNTHASE
(Thymus
vulgaris) 		4 / 6 LEU A 115
ILE A 112
LEU A  99
GLU A 127
 LEU  A 115 ( 0.6A)
ILE  A 112 ( 0.7A)
LEU  A  99 ( 0.6A)
GLU  A 127 ( 0.6A)
 0.85A 4w5nA-5c05A:
undetectable		 4w5nA-5c05A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 5c05 PUTATIVE
GAMMA-TERPINENE
SYNTHASE
(Thymus
vulgaris) 		4 / 8 LEU A 243
LEU A 195
THR A 219
LEU A 222
 LEU  A 243 ( 0.5A)
LEU  A 195 ( 0.6A)
THR  A 219 ( 0.8A)
LEU  A 222 ( 0.6A)
 0.77A 4z90F-5c05A:
5.9
4z90G-5c05A:
5.9
4z90H-5c05A:
3.4
4z90I-5c05A:
5.8
4z90J-5c05A:
5.9		 4z90F-5c05A:
21.23
4z90G-5c05A:
21.23
4z90H-5c05A:
21.23
4z90I-5c05A:
21.23
4z90J-5c05A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 5c05 PUTATIVE
GAMMA-TERPINENE
SYNTHASE
(Thymus
vulgaris) 		3 / 3 ALA A 558
ASN A 561
LEU A 562
 ALA  A 558 ( 0.0A)
ASN  A 561 ( 0.6A)
LEU  A 562 ( 0.6A)
 0.30A 5i1oC-5c05A:
undetectable		 5i1oC-5c05A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 5c05 PUTATIVE
GAMMA-TERPINENE
SYNTHASE
(Thymus
vulgaris) 		3 / 3 ALA A 558
ASN A 561
LEU A 562
 ALA  A 558 ( 0.0A)
ASN  A 561 ( 0.6A)
LEU  A 562 ( 0.6A)
 0.36A 5i1pA-5c05A:
undetectable		 5i1pA-5c05A:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2T_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 5c05 PUTATIVE
GAMMA-TERPINENE
SYNTHASE
(Thymus
vulgaris) 		4 / 8 ALA A 339
THR A 343
THR A 346
ALA A 305
 ALA  A 339 ( 0.0A)
THR  A 343 ( 0.8A)
THR  A 346 ( 0.8A)
ALA  A 305 ( 0.0A)
 0.99A 5x2tI-5c05A:
undetectable
5x2tJ-5c05A:
undetectable
5x2tK-5c05A:
undetectable
5x2tL-5c05A:
undetectable		 5x2tI-5c05A:
12.16
5x2tJ-5c05A:
13.06
5x2tK-5c05A:
12.16
5x2tL-5c05A:
13.06