SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5c0n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 5c0n FAB CA33 HEAVY CHAIN
(Oryctolagus
cuniculus) 		4 / 4 THR H 124
PRO H 154
THR H 123
PRO H 125
 None
 1.31A 1dsdC-5c0nH:
undetectable		 1dsdC-5c0nH:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 5c0n FAB CA33 HEAVY CHAIN
(Oryctolagus
cuniculus) 		4 / 4 THR H 124
PRO H 154
THR H 123
PRO H 125
 None
 1.31A 1dsdC-5c0nH:
undetectable		 1dsdC-5c0nH:
13.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H8S_A_AICA1000_1
(MUTANT AL2 6E7P9G)		 5c0n FAB CA33 HEAVY CHAIN
FAB CA33 LIGHT CHAIN
(Oryctolagus
cuniculus) 		6 / 12 TYR L  36
GLN L  89
PHE L 103
VAL H  36
ALA H  93
TRP H 110
 None
 0.74A 1h8sA-5c0nL:
20.7		 1h8sA-5c0nL:
36.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I9J_H_TESH1010_1
(RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT HEAVY
CHAIN
RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT LIGHT
CHAIN)		 5c0n FAB CA33 HEAVY CHAIN
(Oryctolagus
cuniculus) 		5 / 11 SER H  34
TRP H  46
TYR H  57
TYR H 103
GLY H 106
 None
 1.15A 1i9jH-5c0nH:
27.7
1i9jL-5c0nH:
15.4		 1i9jH-5c0nH:
72.44
1i9jL-5c0nH:
27.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JR1_B_MOAB1333_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 5c0n FAB CA33 HEAVY CHAIN
FAB CA33 LIGHT CHAIN
(Oryctolagus
cuniculus) 		4 / 8 ASP L 170
GLY L 106
GLY H  41
GLN H  38
 None
 0.78A 1jr1B-5c0nL:
undetectable		 1jr1B-5c0nL:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_G_BEZG3385_0
(CES1 PROTEIN)		 5c0n FAB CA33 LIGHT CHAIN
(Oryctolagus
cuniculus) 		3 / 3 SER L 182
VAL L 120
LEU L 141
 None
 0.75A 1yajG-5c0nL:
undetectable		 1yajG-5c0nL:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_L_CSCL1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5c0n FAB CA33 LIGHT CHAIN
(Oryctolagus
cuniculus) 		5 / 12 THR L 107
THR L  85
TYR L 145
GLN L 171
VAL L  19
 None
 1.42A 2vaxL-5c0nL:
0.0		 2vaxL-5c0nL:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		 5c0n FAB CA33 LIGHT CHAIN
(Oryctolagus
cuniculus) 		3 / 3 PHE L  71
TYR L  92
LEU L  47
 None
 0.73A 3keeB-5c0nL:
undetectable		 3keeB-5c0nL:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5c0n FAB CA33 HEAVY CHAIN
(Oryctolagus
cuniculus) 		4 / 7 ARG H  65
ASP H  86
ILE H  79
TYR H  90
 None
 1.30A 5a06B-5c0nH:
undetectable		 5a06B-5c0nH:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5c0n FAB CA33 HEAVY CHAIN
(Oryctolagus
cuniculus) 		4 / 7 ALA H  88
THR H  87
VAL H 116
GLU H  85
 None
 0.76A 5ecmD-5c0nH:
undetectable		 5ecmD-5c0nH:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_B_032B401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 5c0n FAB CA33 HEAVY CHAIN
FAB CA33 LIGHT CHAIN
(Oryctolagus
cuniculus) 		4 / 4 CYH L  90
PHE L 103
ILE H  49
GLY H 106
 None
 1.35A 5hesB-5c0nL:
undetectable		 5hesB-5c0nL:
21.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MTH_A_ACTA302_0
(ANTIBODY FAB HEAVY
CHAIN)		 5c0n FAB CA33 HEAVY CHAIN
(Oryctolagus
cuniculus) 		4 / 5 SER H 119
ALA H 121
PHE H 153
LEU H 177
 None
 0.33A 5mthA-5c0nH:
26.9		 5mthA-5c0nH:
71.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODH_G_ACTG710_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 5c0n FAB CA33 HEAVY CHAIN
(Oryctolagus
cuniculus) 		4 / 4 ARG H  65
ILE H  79
TYR H  90
ILE H  47
 None
 1.42A 5odhG-5c0nH:
undetectable		 5odhG-5c0nH:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 5c0n FAB CA33 HEAVY CHAIN
FAB CA33 LIGHT CHAIN
(Oryctolagus
cuniculus;
Oryctolagus
cuniculus) 		5 / 12 PRO L 118
MET L 180
VAL L 120
ILE L 122
LEU H 131
 None
 1.33A 5tiwB-5c0nL:
undetectable		 5tiwB-5c0nL:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 5c0n FAB CA33 HEAVY CHAIN
(Oryctolagus
cuniculus) 		3 / 3 SER H 210
ALA H 205
VAL H 204
 None
 0.54A 5xiwC-5c0nH:
undetectable		 5xiwC-5c0nH:
16.59