SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5c0s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJM_A_BJMA1_1 (DIPEPTIDYL PEPTIDASE 4)	5c0s	HEMAGGLUTININ, ENVELOPE GLYCOPROTEIN, FIBRITIN FUSION PROTEIN (Escherichia virus T4; Human immunodeficiency virus 1; Influenza A virus)	5 / 12	SER A 248 TYR A 244 TYR A 241 TYR A 239 ASN A 210	None	1.47A	3bjmA-5c0sA: undetectable	3bjmA-5c0sA: 18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W2T_A_LF7A801_1 (DIPEPTIDYL PEPTIDASE 4)	5c0s	HEMAGGLUTININ, ENVELOPE GLYCOPROTEIN, FIBRITIN FUSION PROTEIN (Escherichia virus T4; Human immunodeficiency virus 1; Influenza A virus)	5 / 12	SER A 248 TYR A 244 TYR A 241 TYR A 239 ASN A 210	None	1.50A	3w2tA-5c0sA: undetectable	3w2tA-5c0sA: 18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W2T_B_LF7B801_1 (DIPEPTIDYL PEPTIDASE 4)	5c0s	HEMAGGLUTININ, ENVELOPE GLYCOPROTEIN, FIBRITIN FUSION PROTEIN (Escherichia virus T4; Human immunodeficiency virus 1; Influenza A virus)	5 / 12	SER A 248 TYR A 244 TYR A 241 TYR A 239 ASN A 210	None	1.48A	3w2tB-5c0sA: undetectable	3w2tB-5c0sA: 18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AJQ_A_DB8A800_2 (SERINE/THREONINE-PRO TEIN KINASE 10)	5c0s	HEMAGGLUTININ, ENVELOPE GLYCOPROTEIN, FIBRITIN FUSION PROTEIN (Escherichia virus T4; Human immunodeficiency virus 1; Influenza A virus)	4 / 4	VAL A 103 ILE A 96 ASN A 186 VAL A 30	None	1.24A	5ajqA-5c0sA: undetectable	5ajqA-5c0sA: 21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B1E_B_LF7B801_1 (DIPEPTIDYL PEPTIDASE 4)	5c0s	HEMAGGLUTININ, ENVELOPE GLYCOPROTEIN, FIBRITIN FUSION PROTEIN (Escherichia virus T4; Human immunodeficiency virus 1; Influenza A virus)	5 / 12	SER A 248 TYR A 244 TYR A 241 TYR A 239 ASN A 210	None	1.49A	6b1eB-5c0sA: undetectable	6b1eB-5c0sA: 18.99

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3BJM_A_BJMA1_1","DIPEPTIDYL PEPTIDASE 4","5c0s","HEMAGGLUTININ, ENVELOPE GLYCOPROTEIN, FIBRITIN FUSION PROTEIN","Escherichia virus T4;Human immunodeficiency virus 1;Influenza A virus",5,"SER A 248;TYR A 244;TYR A 241;TYR A 239;ASN A 210","None","1.47A","3bjmA-5c0sA:undetectable","3bjmA-5c0sA:18.99"],["3W2T_A_LF7A801_1","DIPEPTIDYL PEPTIDASE 4","5c0s","HEMAGGLUTININ, ENVELOPE GLYCOPROTEIN, FIBRITIN FUSION PROTEIN","Escherichia virus T4;Human immunodeficiency virus 1;Influenza A virus",5,"SER A 248;TYR A 244;TYR A 241;TYR A 239;ASN A 210","None","1.50A","3w2tA-5c0sA:undetectable","3w2tA-5c0sA:18.52"],["3W2T_B_LF7B801_1","DIPEPTIDYL PEPTIDASE 4","5c0s","HEMAGGLUTININ, ENVELOPE GLYCOPROTEIN, FIBRITIN FUSION PROTEIN","Escherichia virus T4;Human immunodeficiency virus 1;Influenza A virus",5,"SER A 248;TYR A 244;TYR A 241;TYR A 239;ASN A 210","None","1.48A","3w2tB-5c0sA:undetectable","3w2tB-5c0sA:18.52"],["5AJQ_A_DB8A800_2","SERINE\/THREONINE-PROTEIN KINASE 10","5c0s","HEMAGGLUTININ, ENVELOPE GLYCOPROTEIN, FIBRITIN FUSION PROTEIN","Escherichia virus T4;Human immunodeficiency virus 1;Influenza A virus",4,"VAL A 103;ILE A  96;ASN A 186;VAL A  30","None","1.24A","5ajqA-5c0sA:undetectable","5ajqA-5c0sA:21.35"],["6B1E_B_LF7B801_1","DIPEPTIDYL PEPTIDASE 4","5c0s","HEMAGGLUTININ, ENVELOPE GLYCOPROTEIN, FIBRITIN FUSION PROTEIN","Escherichia virus T4;Human immunodeficiency virus 1;Influenza A virus",5,"SER A 248;TYR A 244;TYR A 241;TYR A 239;ASN A 210","None","1.49A","6b1eB-5c0sA:undetectable","6b1eB-5c0sA:18.99"]]