SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5c1e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE)		 5c1e PECTINESTERASE
(Aspergillus
niger) 		4 / 7 TYR A  73
VAL A 102
TYR A  67
GLY A  89
 None
 0.93A 11gsA-5c1eA:
undetectable		 11gsA-5c1eA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 5c1e PECTINESTERASE
(Aspergillus
niger) 		4 / 7 TYR A 259
ASN A 289
ARG A 299
VAL A 257
 None
 1.16A 1wu8A-5c1eA:
undetectable
1wu8C-5c1eA:
undetectable		 1wu8A-5c1eA:
23.69
1wu8C-5c1eA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 5c1e PECTINESTERASE
(Aspergillus
niger) 		3 / 3 THR A 213
PRO A 250
TYR A 284
 None
 0.85A 2dxrA-5c1eA:
undetectable		 2dxrA-5c1eA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_A_EAAA0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 5c1e PECTINESTERASE
(Aspergillus
niger) 		4 / 8 TYR A  73
VAL A 102
TYR A  67
GLY A  89
 None
 0.90A 2gssA-5c1eA:
undetectable		 2gssA-5c1eA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_B_EAAB0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 5c1e PECTINESTERASE
(Aspergillus
niger) 		4 / 8 TYR A  73
VAL A 102
TYR A  67
GLY A  89
 None
 0.91A 2gssB-5c1eA:
undetectable		 2gssB-5c1eA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_A_EAAA210_1
(GLUTATHIONE
S-TRANSFERASE P)		 5c1e PECTINESTERASE
(Aspergillus
niger) 		4 / 8 TYR A  73
VAL A 102
TYR A  67
GLY A  89
 None
 0.92A 3n9jA-5c1eA:
undetectable		 3n9jA-5c1eA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA803_1
(CATALASE-PEROXIDASE)		 5c1e PECTINESTERASE
(Aspergillus
niger) 		4 / 4 ASP A  99
THR A  94
VAL A 101
SER A  30
 None
 1.19A 3wxoA-5c1eA:
undetectable		 3wxoA-5c1eA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_0
(WBDD)		 5c1e PECTINESTERASE
(Aspergillus
niger) 		5 / 12 ILE A 228
ASN A 230
ILE A 258
VAL A 309
ILE A 305
 None
 0.99A 4ax8A-5c1eA:
undetectable		 4ax8A-5c1eA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_C_ACTC1113_0
(BLR5658 PROTEIN)		 5c1e PECTINESTERASE
(Aspergillus
niger) 		4 / 4 ASN A 207
ALA A 187
GLY A 186
THR A 169
 None
 1.33A 4bboC-5c1eA:
undetectable		 4bboC-5c1eA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0R_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 5c1e PECTINESTERASE
(Aspergillus
niger) 		5 / 12 VAL A 122
LEU A  77
ILE A  50
PHE A 129
MET A 131
 None
 0.87A 4y0rA-5c1eA:
undetectable		 4y0rA-5c1eA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMF_A_6U9A1301_1
(ION TRANSPORT
PROTEIN)		 5c1e PECTINESTERASE
(Aspergillus
niger) 		4 / 6 GLY A 200
GLU A 201
PHE A 199
ILE A 233
 SO4  A 402 (-3.4A)
SO4  A 402 ( 4.9A)
None
None
 0.88A 5kmfA-5c1eA:
undetectable
5kmfC-5c1eA:
undetectable		 5kmfA-5c1eA:
21.77
5kmfC-5c1eA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5c1e PECTINESTERASE
(Aspergillus
niger) 		5 / 9 VAL A 136
ILE A  50
GLY A  51
LEU A  54
PHE A 158
 None
 0.65A 5vkqC-5c1eA:
undetectable
5vkqD-5c1eA:
undetectable		 5vkqC-5c1eA:
10.57
5vkqD-5c1eA:
10.57