SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5c1m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJP_A_KLNA413_1
(CYTOCHROME P450
113A1)		 5c1m MU-TYPE OPIOID
RECEPTOR
(Mus
musculus) 		5 / 12 ALA A 113
LEU A 116
ALA A 117
THR A 120
ILE A 142
 None
 1.26A 2jjpA-5c1mA:
1.8		 2jjpA-5c1mA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_C_PM6C1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5c1m MU-TYPE OPIOID
RECEPTOR
(Mus
musculus) 		4 / 6 PHE A 178
THR A 180
ALA A 168
ALA A 175
 P6G  A 406 (-4.6A)
None
None
None
 1.23A 3ns1C-5c1mA:
undetectable		 3ns1C-5c1mA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 5c1m NANOBODY 39
(Lama
glama) 		3 / 3 PRO B  33
MET B  34
TYR B  32
 None
 1.01A 4qa2B-5c1mB:
undetectable		 4qa2B-5c1mB:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_H_SAMH301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5c1m MU-TYPE OPIOID
RECEPTOR
NANOBODY 39
(Mus
musculus;
Lama
glama) 		5 / 12 ASP A 340
THR A 103
THR A  97
SER B  50
TYR B  60
 None
 1.31A 5hfjH-5c1mA:
undetectable		 5hfjH-5c1mA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5c1m MU-TYPE OPIOID
RECEPTOR
(Mus
musculus) 		5 / 12 GLY A 253
VAL A 282
VAL A 286
ILE A 167
VAL A 163
 None
None
None
None
P6G  A 406 ( 4.7A)
 1.02A 5n0sA-5c1mA:
undetectable		 5n0sA-5c1mA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5c1m MU-TYPE OPIOID
RECEPTOR
(Mus
musculus) 		5 / 12 GLY A 253
VAL A 282
VAL A 286
ILE A 167
VAL A 163
 None
None
None
None
P6G  A 406 ( 4.7A)
 1.06A 5n0tA-5c1mA:
undetectable		 5n0tA-5c1mA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5c1m MU-TYPE OPIOID
RECEPTOR
(Mus
musculus) 		5 / 12 GLY A 253
VAL A 282
VAL A 286
ILE A 167
VAL A 163
 None
None
None
None
P6G  A 406 ( 4.7A)
 0.99A 5n0wB-5c1mA:
undetectable		 5n0wB-5c1mA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5c1m MU-TYPE OPIOID
RECEPTOR
(Mus
musculus) 		5 / 12 GLY A 253
VAL A 282
VAL A 286
ILE A 167
VAL A 163
 None
None
None
None
P6G  A 406 ( 4.7A)
 0.97A 5n4iA-5c1mA:
undetectable		 5n4iA-5c1mA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5c1m MU-TYPE OPIOID
RECEPTOR
(Mus
musculus) 		3 / 3 GLY A  52
THR A 311
PRO A  58
 None
None
YCM  A  57 ( 2.6A)
 0.61A 5v5zA-5c1mA:
1.3		 5v5zA-5c1mA:
20.79