SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5c22'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_CCSB381_0
(ESTROGEN RECEPTOR)		 5c22 CHROMOSOMAL
HEMOLYSIN D
(Escherichia
coli) 		3 / 3 GLU A 263
ALA A 265
SER A 230
 None
 0.70A 1errB-5c22A:
undetectable		 1errB-5c22A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_A_HSMA303_1
(NITROPHORIN 1)		 5c22 CHROMOSOMAL
HEMOLYSIN D
(Escherichia
coli) 		4 / 5 GLU A 319
LEU A 313
LEU A 316
LEU A 314
 None
 1.17A 1np1A-5c22A:
undetectable		 1np1A-5c22A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR0_A_SAMA401_0
(ARSENIC
METHYLTRANSFERASE)		 5c22 CHROMOSOMAL
HEMOLYSIN D
(Escherichia
coli) 		5 / 12 GLY A 115
MET A 357
LEU A 341
ILE A 359
VAL A 118
 None
 1.15A 4fr0A-5c22A:
undetectable		 4fr0A-5c22A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5c22 CHROMOSOMAL
HEMOLYSIN D
(Escherichia
coli) 		3 / 3 GLN A 199
TRP A 198
VAL A 292
 None
 0.85A 6auuA-5c22A:
2.4		 6auuA-5c22A:
21.43