SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5c24'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD8_0
(GRAMICIDIN A)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
3 / 3 TRP B 266
VAL B 261
TRP B 426
None
1.29A 1c4dC-5c24B:
undetectable
1c4dD-5c24B:
undetectable
1c4dC-5c24B:
3.19
1c4dD-5c24B:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4002_1
(SERUM ALBUMIN)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
3 / 3 PHE B 116
LEU B 120
SER B 156
None
0.88A 1e7aA-5c24B:
undetectable
1e7aA-5c24B:
21.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FK9_A_EFZA999_1
(HIV-1 RT, A-CHAIN)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 10 LYS B 103
VAL B 106
VAL B 179
TYR B 188
GLY B 190
None
0.84A 1fk9A-5c24B:
11.5
1fk9A-5c24B:
96.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FK9_A_EFZA999_1
(HIV-1 RT, A-CHAIN)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 10 LYS B 103
VAL B 179
TYR B 181
TYR B 188
GLY B 190
None
0.72A 1fk9A-5c24B:
11.5
1fk9A-5c24B:
96.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKP_A_NVPA999_1
(HIV-1 RT, A-CHAIN)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 11 VAL B 106
VAL B 179
TYR B 181
TYR B 188
GLY B 190
None
0.34A 1fkpA-5c24B:
6.9
1fkpA-5c24B:
96.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IKW_A_EFZA2000_1
(POL POLYPROTEIN)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 10 LYS B 103
VAL B 106
VAL B 179
TYR B 188
GLY B 190
None
0.84A 1ikwA-5c24B:
14.9
1ikwA-5c24B:
96.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IKW_A_EFZA2000_1
(POL POLYPROTEIN)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 10 LYS B 103
VAL B 179
TYR B 181
TYR B 188
GLY B 190
None
0.70A 1ikwA-5c24B:
14.9
1ikwA-5c24B:
96.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JKH_A_EFZA999_1
(HIV-1 RT, A-CHAIN
HIV-1 RT, B-CHAIN)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 11 LYS B 103
VAL B 106
VAL B 179
TYR B 188
GLY B 190
None
0.87A 1jkhA-5c24B:
12.8
1jkhB-5c24B:
51.2
1jkhA-5c24B:
96.46
1jkhB-5c24B:
96.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LW0_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
6 / 10 LYS B 103
VAL B 106
VAL B 179
TYR B 181
TYR B 188
GLY B 190
None
0.61A 1lw0A-5c24B:
11.1
1lw0A-5c24B:
96.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LWC_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
6 / 11 LYS B 103
VAL B 106
VAL B 179
TYR B 181
TYR B 188
GLY B 190
None
0.68A 1lwcA-5c24B:
10.4
1lwcA-5c24B:
96.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LWE_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
4 / 7 VAL B 106
TYR B 181
TYR B 188
GLY B 190
None
0.47A 1lweA-5c24B:
18.9
1lweA-5c24B:
96.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LWF_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 9 VAL B 106
VAL B 179
TYR B 181
TYR B 188
GLY B 190
None
0.47A 1lwfA-5c24B:
5.4
1lwfA-5c24B:
95.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S1U_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
6 / 10 LYS B 103
VAL B 106
VAL B 179
TYR B 181
TYR B 188
GLY B 190
None
0.59A 1s1uA-5c24B:
14.2
1s1uA-5c24B:
96.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
4 / 8 VAL B 106
TYR B 181
TYR B 188
GLY B 190
None
0.39A 1s1xA-5c24B:
12.4
1s1xA-5c24B:
96.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
4 / 7 ASP B 110
MET B 184
ASP B 185
ASP B 186
None
1.43A 1t03A-5c24B:
10.9
1t03A-5c24B:
96.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
4 / 7 ASP B 110
MET B 184
ASP B 186
LYS B 227
None
1.39A 1t03A-5c24B:
10.9
1t03A-5c24B:
96.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
4 / 7 TYR B 183
MET B 184
ASP B 185
ASP B 186
None
1.09A 1t03A-5c24B:
10.9
1t03A-5c24B:
96.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
4 / 6 LEU B 109
MET B 164
THR B 165
LEU B 168
None
0.79A 1v54A-5c24B:
2.2
1v54J-5c24B:
undetectable
1v54A-5c24B:
20.11
1v54J-5c24B:
10.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VRT_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 9 VAL B 106
VAL B 179
TYR B 181
TYR B 188
GLY B 190
None
0.27A 1vrtA-5c24B:
10.9
1vrtA-5c24B:
96.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_1
(MINERALOCORTICOID
RECEPTOR)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 12 LEU B  80
GLN B 151
MET B 184
ARG B  72
THR B  84
None
1.45A 1ya3B-5c24B:
undetectable
1ya3B-5c24B:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
4 / 6 LEU B 109
MET B 164
THR B 165
LEU B 168
None
0.78A 2dyrA-5c24B:
2.3
2dyrJ-5c24B:
undetectable
2dyrA-5c24B:
20.11
2dyrJ-5c24B:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
4 / 6 LEU B 109
MET B 164
THR B 165
LEU B 168
None
0.77A 2eijA-5c24B:
2.4
2eijJ-5c24B:
undetectable
2eijA-5c24B:
20.11
2eijJ-5c24B:
10.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HND_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
6 / 10 LYS B 103
VAL B 106
VAL B 179
TYR B 181
TYR B 188
GLY B 190
None
0.69A 2hndA-5c24B:
18.4
2hndA-5c24B:
96.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HNY_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
6 / 10 LYS B 103
VAL B 106
VAL B 179
TYR B 181
TYR B 188
GLY B 190
None
0.70A 2hnyA-5c24B:
10.9
2hnyA-5c24B:
96.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZD1_A_T27A557_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 12 LYS B 103
VAL B 106
VAL B 179
TYR B 181
TYR B 188
None
0.77A 2zd1A-5c24B:
11.7
2zd1A-5c24B:
96.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
4 / 6 LEU B 109
MET B 164
THR B 165
LEU B 168
None
0.79A 3abmA-5c24B:
2.4
3abmJ-5c24B:
undetectable
3abmA-5c24B:
20.11
3abmJ-5c24B:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_2
(PHOSPHOLIPASE A2)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
4 / 8 LYS B 166
PRO B 150
PHE B  77
TRP B 153
None
1.32A 3bjwD-5c24B:
undetectable
3bjwD-5c24B:
14.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HVT_A_NVPA557_1
(HIV-1 REVERSE
TRANSCRIPTASE
(SUBUNIT P66))
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 9 LYS B 103
VAL B 106
TYR B 181
TYR B 188
GLY B 190
None
1.03A 3hvtA-5c24B:
9.2
3hvtA-5c24B:
96.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LP0_A_NVPA701_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 9 VAL B 106
VAL B 179
TYR B 181
TYR B 188
GLY B 190
None
0.61A 3lp0A-5c24B:
8.0
3lp0A-5c24B:
96.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LP1_A_NVPA701_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 10 VAL B 106
VAL B 179
TYR B 181
TYR B 188
GLY B 190
None
0.54A 3lp1A-5c24B:
11.8
3lp1A-5c24B:
96.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 12 LYS B 103
VAL B 106
VAL B 179
TYR B 181
GLY B 190
None
1.15A 3mecA-5c24B:
12.0
3mecA-5c24B:
96.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
6 / 12 LYS B 103
VAL B 106
VAL B 179
TYR B 181
TYR B 188
GLY B 190
None
0.90A 3mecA-5c24B:
12.0
3mecA-5c24B:
96.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 12 VAL B 106
VAL B 179
TYR B 181
TYR B 188
GLY B 190
None
0.74A 3medA-5c24B:
8.8
3medB-5c24B:
17.7
3medA-5c24B:
96.46
3medB-5c24B:
96.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MEE_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 12 LYS B 103
VAL B 106
VAL B 179
TYR B 181
TYR B 188
None
0.98A 3meeA-5c24B:
14.1
3meeA-5c24B:
96.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
3 / 3 LYS B 374
ARG B 356
ASP B 237
None
1.39A 3o7wA-5c24B:
undetectable
3o7wA-5c24B:
21.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QIP_A_NVPA561_1
(REVERSE HIV-1
REVERSE
TRANSCRIPTASE P66)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
6 / 10 LYS B 103
VAL B 106
VAL B 179
TYR B 181
TYR B 188
GLY B 190
None
0.67A 3qipA-5c24B:
11.8
3qipA-5c24B:
96.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
3 / 3 LYS B 388
GLU B 413
TRP B 414
None
1.28A 3v4tH-5c24B:
undetectable
3v4tH-5c24B:
22.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B3O_A_EFZA1557_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 9 LYS B 103
VAL B 106
TYR B 181
TYR B 188
GLY B 190
None
0.79A 4b3oA-5c24B:
10.7
4b3oA-5c24B:
95.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
4 / 7 ARG B 358
TYR B 232
LEU B 234
TYR B 339
None
1.29A 4f8yC-5c24B:
undetectable
4f8yD-5c24B:
undetectable
4f8yC-5c24B:
17.96
4f8yD-5c24B:
17.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G1Q_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 12 LYS B 103
VAL B 106
VAL B 179
TYR B 181
TYR B 188
None
0.71A 4g1qA-5c24B:
11.9
4g1qA-5c24B:
96.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ICL_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 12 LYS B 103
VAL B 106
VAL B 179
TYR B 181
TYR B 188
None
0.71A 4iclA-5c24B:
10.8
4iclA-5c24B:
96.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ID5_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 12 LYS B 103
VAL B 106
VAL B 179
TYR B 181
TYR B 188
None
0.73A 4id5A-5c24B:
9.5
4id5A-5c24B:
96.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IDK_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 12 LYS B 103
VAL B 106
VAL B 179
TYR B 181
TYR B 188
None
0.69A 4idkA-5c24B:
11.8
4idkA-5c24B:
96.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFV_A_T27A601_1
(EXORIBONUCLEASE H,
P66 RT)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 12 LYS B 103
VAL B 106
VAL B 179
TYR B 181
TYR B 188
None
0.72A 4ifvA-5c24B:
10.7
4ifvA-5c24B:
96.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFY_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 12 LYS B 103
VAL B 106
VAL B 179
TYR B 181
TYR B 188
None
0.69A 4ifyA-5c24B:
10.9
4ifyA-5c24B:
96.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IG3_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 12 LYS B 103
VAL B 106
VAL B 179
TYR B 181
TYR B 188
None
0.76A 4ig3A-5c24B:
19.4
4ig3A-5c24B:
96.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KFB_A_T27A607_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H,
EXORIBONUCLEA P66 RT)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 12 LYS B 103
VAL B 106
VAL B 179
TYR B 181
TYR B 188
None
0.64A 4kfbA-5c24B:
10.7
4kfbA-5c24B:
96.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
4 / 8 THR B 377
LEU B 234
VAL B 106
ASP B 186
None
1.12A 4l4eA-5c24B:
undetectable
4l4eA-5c24B:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
4 / 8 THR B 377
LEU B 234
VAL B 106
ASP B 186
None
1.09A 4l4fA-5c24B:
undetectable
4l4fA-5c24B:
20.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PWD_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
4 / 8 VAL B 106
VAL B 179
TYR B 181
TYR B 188
None
0.41A 4pwdC-5c24B:
10.4
4pwdC-5c24B:
96.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Q0B_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 8 LYS B 103
VAL B 106
VAL B 179
TYR B 181
TYR B 188
None
0.78A 4q0bA-5c24B:
10.9
4q0bA-5c24B:
96.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Q0B_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 9 LYS B 103
VAL B 106
VAL B 179
TYR B 181
TYR B 188
None
0.67A 4q0bC-5c24B:
9.9
4q0bC-5c24B:
96.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYM_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 12 LYS B 103
VAL B 106
VAL B 179
TYR B 181
TYR B 188
None
0.73A 5cymA-5c24B:
11.7
5cymA-5c24B:
96.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYQ_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 12 LYS B 103
VAL B 106
VAL B 179
TYR B 181
TYR B 188
None
0.75A 5cyqA-5c24B:
10.8
5cyqA-5c24B:
96.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
3 / 3 TRP B 414
GLU B 413
ASP B  76
None
0.97A 5gqbA-5c24B:
undetectable
5gqbA-5c24B:
20.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HBM_A_NVPA601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 11 VAL B 106
VAL B 179
TYR B 181
TYR B 188
GLY B 190
None
0.30A 5hbmA-5c24B:
11.9
5hbmA-5c24B:
96.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
4 / 6 LEU B 109
MET B 164
THR B 165
LEU B 168
None
0.76A 5x1fA-5c24B:
2.5
5x1fJ-5c24B:
undetectable
5x1fA-5c24B:
20.11
5x1fJ-5c24B:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0L_B_TA1B502_1
(TUBULIN BETA CHAIN)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 12 LEU B 205
LEU B 168
PRO B  97
GLY B  99
LEU B 100
None
1.01A 6b0lB-5c24B:
undetectable
6b0lB-5c24B:
12.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSG_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 10 LYS B 103
VAL B 106
VAL B 179
TYR B 188
GLY B 190
None
1.06A 6bsgA-5c24B:
11.0
6bsgA-5c24B:
98.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSG_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 10 LYS B 103
VAL B 179
TYR B 181
TYR B 188
GLY B 190
None
0.84A 6bsgA-5c24B:
11.0
6bsgA-5c24B:
98.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 10 LYS B 103
VAL B 106
VAL B 179
TYR B 188
GLY B 190
None
1.07A 6bsiA-5c24B:
11.2
6bsiA-5c24B:
98.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 10 LYS B 103
VAL B 179
TYR B 181
TYR B 188
GLY B 190
None
0.82A 6bsiA-5c24B:
11.2
6bsiA-5c24B:
98.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus
1)
5 / 12 LYS B 103
VAL B 106
VAL B 179
TYR B 181
TYR B 188
None
0.73A 6eliA-5c24B:
11.9
6eliA-5c24B:
100.00