SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5c2v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_2
(NEURAMINIDASE)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		3 / 3 ASP A 292
ARG A 216
ILE A 225
 None
 0.87A 1a4gB-5c2vA:
6.3		 1a4gB-5c2vA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB8_0
(GRAMICIDIN A)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		3 / 3 VAL A 746
VAL A 735
TRP A 747
 None
 0.53A 1bdwA-5c2vA:
undetectable
1bdwB-5c2vA:
undetectable		 1bdwA-5c2vA:
2.33
1bdwB-5c2vA:
2.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_1
(FTSJ)		 5c2v HYDRAZINE SYNTHASE
BETA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		3 / 3 ASP B 337
ASP B 281
ASP B 333
 None
 0.78A 1eizA-5c2vB:
undetectable		 1eizA-5c2vB:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_1
(FTSJ)		 5c2v HYDRAZINE SYNTHASE
BETA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		3 / 3 ASP B 337
ASP B 281
ASP B 333
 None
 0.74A 1ej0A-5c2vB:
undetectable		 1ej0A-5c2vB:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTB_A_PZQA901_0
(GLUTATHIONE
S-TRANSFERASE)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		3 / 3 GLN A 468
TYR A 591
ARG A 297
 None
CL  A 901 ( 2.9A)
None
 0.84A 1gtbA-5c2vA:
undetectable		 1gtbA-5c2vA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		5 / 12 TRP A 787
GLY A 791
ALA A 739
GLY A 524
TYR A 716
 None
 1.20A 1kiaB-5c2vA:
undetectable		 1kiaB-5c2vA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		3 / 3 ARG A 227
ILE A 163
TRP A 423
 None
 1.12A 1m8eB-5c2vA:
undetectable		 1m8eB-5c2vA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA442_1
(ALPHA AMYLASE)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		5 / 11 GLY A 791
GLY A 524
GLN A 793
GLY A 731
GLY A 732
 None
 0.97A 1mxgA-5c2vA:
undetectable		 1mxgA-5c2vA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4H_A_REAA500_1
(NUCLEAR RECEPTOR
ROR-BETA)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		5 / 11 CYH A 583
ILE A 459
ALA A 603
VAL A 489
LEU A 575
 HEC  A 905 (-1.8A)
None
None
None
None
 1.19A 1n4hA-5c2vA:
undetectable		 1n4hA-5c2vA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		3 / 3 ARG A 227
ILE A 163
TRP A 423
 None
 1.15A 1nodB-5c2vA:
undetectable		 1nodB-5c2vA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		3 / 3 ARG A 227
ILE A 163
TRP A 423
 None
 1.09A 1qomA-5c2vA:
undetectable		 1qomA-5c2vA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRD_A_MIYA2001_1
(ACRB)		 5c2v HYDRAZINE SYNTHASE
BETA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		5 / 9 GLN B  66
PHE B  50
GLU B  84
ALA B 371
PHE B 374
 None
 1.15A 2drdA-5c2vB:
undetectable		 2drdA-5c2vB:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		3 / 3 ARG A 227
ILE A 163
TRP A 423
 None
 1.16A 2nodB-5c2vA:
undetectable		 2nodB-5c2vA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
HYDRAZINE SYNTHASE
BETA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis;
Candidatus
Kuenenia
stuttgartiensis) 		5 / 12 GLY B 353
GLY A  34
THR B 379
ILE B 381
VAL B 312
 None
 0.93A 2oxtC-5c2vB:
undetectable		 2oxtC-5c2vB:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_A_ASDA1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		4 / 8 ILE A 236
GLY A 235
LEU A 233
PHE A 195
 None
 0.83A 2vctA-5c2vA:
undetectable		 2vctA-5c2vA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_B_ASDB1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		4 / 8 ILE A 236
GLY A 235
LEU A 233
PHE A 195
 None
 0.82A 2vctB-5c2vA:
undetectable		 2vctB-5c2vA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_C_IBPC1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		5 / 10 TRP A 607
GLY A 580
GLY A 456
GLN A 548
THR A 546
 None
 1.15A 2wd9C-5c2vA:
undetectable		 2wd9C-5c2vA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		5 / 12 ASP A 257
GLN A 315
TYR A 212
ASP A 108
PHE A 107
 None
 1.48A 2x2iA-5c2vA:
undetectable		 2x2iA-5c2vA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		4 / 7 GLN A  58
LEU A  60
LEU A  99
LEU A  88
 None
 0.67A 3bgdB-5c2vA:
undetectable		 3bgdB-5c2vA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_1
(N,N-DIMETHYLTRANSFER
ASE)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		3 / 3 TYR A 495
GLU A 786
ASP A 779
 None
 0.78A 3bxoA-5c2vA:
undetectable		 3bxoA-5c2vA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E68_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		3 / 3 ARG A 227
ILE A 163
TRP A 423
 None
 1.13A 3e68A-5c2vA:
undetectable		 3e68A-5c2vA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		3 / 3 ARG A 227
ILE A 163
TRP A 423
 None
 1.10A 3e6tB-5c2vA:
undetectable		 3e6tB-5c2vA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		3 / 3 VAL A 232
LYS A 223
HIS A 240
 None
 0.93A 3elzA-5c2vA:
0.0		 3elzA-5c2vA:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		5 / 12 SER A 523
TYR A 716
ILE A 492
ILE A 788
VAL A 735
 None
 1.21A 3g8iA-5c2vA:
undetectable		 3g8iA-5c2vA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
HYDRAZINE SYNTHASE
BETA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis;
Candidatus
Kuenenia
stuttgartiensis) 		5 / 12 ARG B 336
PRO B 279
GLY A 593
ILE A 299
LEU B 283
 BET  B 403 (-4.3A)
None
None
None
None
 1.09A 3iv6C-5c2vB:
undetectable		 3iv6C-5c2vB:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		4 / 8 PHE A 206
SER A 254
ARG A 518
VAL A 271
 None
 1.12A 3jx1A-5c2vA:
undetectable
3jx1B-5c2vA:
undetectable		 3jx1A-5c2vA:
18.12
3jx1B-5c2vA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		4 / 8 PHE A 206
SER A 254
ARG A 518
VAL A 271
 None
 1.11A 3nlrA-5c2vA:
undetectable
3nlrB-5c2vA:
undetectable		 3nlrA-5c2vA:
18.25
3nlrB-5c2vA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		4 / 8 PHE A 206
SER A 254
ARG A 518
VAL A 271
 None
 1.11A 3nlyA-5c2vA:
undetectable
3nlyB-5c2vA:
undetectable		 3nlyA-5c2vA:
18.00
3nlyB-5c2vA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_G_ACTG601_0
(CHOLINE OXIDASE)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		4 / 6 ALA A 711
HIS A 512
VAL A 706
ASN A 717
 None
 1.18A 3nneG-5c2vA:
undetectable		 3nneG-5c2vA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_0
(YAEB-LIKE PROTEIN
RPA0152)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		5 / 12 LEU A 745
LEU A 697
PRO A 695
GLY A 698
SER A 713
 HEC  A 906 (-4.8A)
None
None
None
None
 1.38A 3okxA-5c2vA:
undetectable		 3okxA-5c2vA:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q87_B_SAMB300_0
(N6 ADENINE SPECIFIC
DNA METHYLASE)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		5 / 12 GLY A 662
ASP A 640
ASP A 666
LEU A 665
PRO A 452
 None
 1.23A 3q87B-5c2vA:
undetectable		 3q87B-5c2vA:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
HYDRAZINE SYNTHASE
BETA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis;
Candidatus
Kuenenia
stuttgartiensis) 		5 / 12 TYR A 295
GLU B 253
GLN B 258
VAL B 259
ASP A 346
 None
 1.12A 3qowA-5c2vA:
undetectable		 3qowA-5c2vA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXY_B_SAMB6735_0
(N-LYSINE
METHYLTRANSFERASE
SETD6
TRANSCRIPTION FACTOR
P65)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		5 / 11 ALA A 160
GLY A 161
TYR A 112
TYR A 157
LYS A 117
 None
 1.49A 3qxyB-5c2vA:
undetectable
3qxyQ-5c2vA:
undetectable		 3qxyB-5c2vA:
18.63
3qxyQ-5c2vA:
2.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		4 / 8 PHE A 206
SER A 254
ARG A 518
VAL A 271
 None
 1.12A 3rqlA-5c2vA:
undetectable
3rqlB-5c2vA:
undetectable		 3rqlA-5c2vA:
18.00
3rqlB-5c2vA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB504_1
(HEMOLYTIC LECTIN
CEL-III)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		4 / 5 GLU A 381
GLY A 361
TYR A 364
GLN A 339
 None
 0.87A 3w9tB-5c2vA:
undetectable		 3w9tB-5c2vA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		4 / 5 GLU A 329
GLY A 308
TYR A 300
GLU A 306
 None
 1.47A 3w9tC-5c2vA:
undetectable		 3w9tC-5c2vA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD506_1
(HEMOLYTIC LECTIN
CEL-III)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		4 / 5 GLU A 381
GLY A 361
TYR A 364
GLN A 339
 None
 0.89A 3w9tD-5c2vA:
undetectable		 3w9tD-5c2vA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE505_1
(HEMOLYTIC LECTIN
CEL-III)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		4 / 5 GLU A 381
GLY A 361
TYR A 364
GLN A 339
 None
 0.90A 3w9tE-5c2vA:
undetectable		 3w9tE-5c2vA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG505_1
(HEMOLYTIC LECTIN
CEL-III)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		4 / 5 GLU A 381
GLY A 361
TYR A 364
GLN A 339
 None
 0.91A 3w9tG-5c2vA:
undetectable		 3w9tG-5c2vA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQE_B_DXCB1079_0
(PROTEIN PRGI, CELL
INVASION PROTEIN
SIPD)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		5 / 11 PRO A 474
SER A 738
THR A 571
LEU A 570
TYR A 554
 None
None
HEC  A 905 (-3.7A)
HEC  A 905 (-4.1A)
None
 1.25A 3zqeA-5c2vA:
undetectable
3zqeB-5c2vA:
undetectable		 3zqeA-5c2vA:
17.24
3zqeB-5c2vA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		4 / 8 PHE A 206
SER A 254
ARG A 518
VAL A 271
 None
 1.12A 4capA-5c2vA:
undetectable
4capB-5c2vA:
undetectable		 4capA-5c2vA:
18.00
4capB-5c2vA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		4 / 8 PHE A 206
SER A 254
ARG A 518
VAL A 271
 None
 1.19A 4d32A-5c2vA:
undetectable
4d32B-5c2vA:
undetectable		 4d32A-5c2vA:
18.00
4d32B-5c2vA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		 5c2v HYDRAZINE SYNTHASE
BETA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		5 / 11 THR B 232
VAL B 264
ILE B 266
MET B 317
LEU B 321
 None
 1.27A 4lhmA-5c2vB:
undetectable		 4lhmA-5c2vB:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_A_FOLA301_1
(FOLATE RECEPTOR
ALPHA)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		3 / 3 ASP A 108
TRP A 407
SER A 366
 None
 0.91A 4lrhA-5c2vA:
undetectable		 4lrhA-5c2vA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_B_ADNB501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		4 / 5 GLN A 315
THR A 319
LEU A 356
LEU A 340
 None
 1.02A 4lvcB-5c2vA:
undetectable		 4lvcB-5c2vA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_A_PAUA301_0
(TYPE III
PANTOTHENATE KINASE)		 5c2v HYDRAZINE SYNTHASE
BETA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		5 / 12 ASN B 263
GLY B 288
THR B 313
ILE B 304
GLN B 243
 None
 1.24A 4o5fA-5c2vB:
undetectable
4o5fB-5c2vB:
undetectable		 4o5fA-5c2vB:
21.11
4o5fB-5c2vB:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 5c2v HYDRAZINE SYNTHASE
BETA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		5 / 12 GLN B 243
ASN B 263
GLY B 288
THR B 313
ILE B 304
 None
 1.21A 4o5fA-5c2vB:
undetectable
4o5fB-5c2vB:
undetectable		 4o5fA-5c2vB:
21.11
4o5fB-5c2vB:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_B_SAMB401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 5c2v HYDRAZINE SYNTHASE
BETA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		5 / 12 ASP B  57
GLY B 100
ASP B  99
ILE B 118
ASP B 117
 None
 1.14A 4pghB-5c2vB:
undetectable		 4pghB-5c2vB:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_B_ACTB1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		4 / 5 ARG A 277
GLY A 282
ALA A 273
GLY A 280
 HEC  A 905 (-3.8A)
None
None
None
 0.97A 4u9uB-5c2vA:
undetectable		 4u9uB-5c2vA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		4 / 8 PHE A 206
SER A 254
ARG A 518
VAL A 271
 None
 1.16A 4v3yA-5c2vA:
undetectable
4v3yB-5c2vA:
undetectable		 4v3yA-5c2vA:
18.00
4v3yB-5c2vA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP1_A_LDPA708_1
(DOPAMINE
TRANSPORTER, ISOFORM
B)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		5 / 10 ASP A 373
ALA A  40
ASP A  44
SER A  46
GLY A  47
 None
 1.38A 4xp1A-5c2vA:
undetectable		 4xp1A-5c2vA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB401_0
(GLYCINE OXIDASE)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		4 / 6 PHE A 626
GLY A 563
TYR A 632
ALA A 488
 None
 1.00A 4yshB-5c2vA:
undetectable		 4yshB-5c2vA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_1
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 5c2v HYDRAZINE SYNTHASE
BETA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		5 / 12 ALA B  93
SER B  94
VAL B 105
VAL B 378
GLU B  84
 None
 1.26A 4zj8A-5c2vB:
undetectable		 4zj8A-5c2vB:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_A_PAUA302_0
(TYPE III
PANTOTHENATE KINASE)		 5c2v HYDRAZINE SYNTHASE
BETA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		5 / 12 ASN B 263
GLY B 288
THR B 313
ILE B 304
GLN B 243
 None
 1.23A 5b8hA-5c2vB:
undetectable
5b8hB-5c2vB:
undetectable		 5b8hA-5c2vB:
22.47
5b8hB-5c2vB:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 5c2v HYDRAZINE SYNTHASE
BETA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		5 / 12 GLN B 243
ASN B 263
GLY B 288
THR B 313
ILE B 304
 None
 1.22A 5b8hA-5c2vB:
undetectable
5b8hB-5c2vB:
undetectable		 5b8hA-5c2vB:
22.47
5b8hB-5c2vB:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 5c2v HYDRAZINE SYNTHASE
BETA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		4 / 5 THR B 313
GLY B 305
HIS B 310
ASP B 287
 None
 1.19A 5c0oH-5c2vB:
undetectable		 5c0oH-5c2vB:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_A_PAUA602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
HYDRAZINE SYNTHASE
BETA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis;
Candidatus
Kuenenia
stuttgartiensis) 		4 / 7 GLU A 306
GLY A 593
GLY B 340
TYR A 300
 None
 0.79A 5e26A-5c2vA:
undetectable
5e26B-5c2vA:
undetectable		 5e26A-5c2vA:
19.27
5e26B-5c2vA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_B_PAUB601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
HYDRAZINE SYNTHASE
BETA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis;
Candidatus
Kuenenia
stuttgartiensis) 		4 / 7 TYR A 300
GLU A 306
GLY A 593
GLY B 340
 None
 0.77A 5e26A-5c2vA:
undetectable
5e26B-5c2vA:
undetectable		 5e26A-5c2vA:
19.27
5e26B-5c2vA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
HYDRAZINE SYNTHASE
BETA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis;
Candidatus
Kuenenia
stuttgartiensis) 		4 / 7 GLU A 306
GLY A 593
GLY B 340
TYR A 300
 None
 0.81A 5e26C-5c2vA:
undetectable
5e26D-5c2vA:
undetectable		 5e26C-5c2vA:
19.27
5e26D-5c2vA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_D_PAUD601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
HYDRAZINE SYNTHASE
BETA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis;
Candidatus
Kuenenia
stuttgartiensis) 		4 / 8 TYR A 300
GLU A 306
GLY A 593
GLY B 340
 None
 0.79A 5e26C-5c2vA:
undetectable
5e26D-5c2vA:
undetectable		 5e26C-5c2vA:
19.27
5e26D-5c2vA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HQA_A_ACRA705_2
(ALPHA-GLUCOSIDASE)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
HYDRAZINE SYNTHASE
BETA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		4 / 8 ASN B 284
PHE A 349
GLU A 306
THR A 319
 None
 1.46A 5hqaA-5c2vB:
4.0		 5hqaA-5c2vB:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 5c2v HYDRAZINE SYNTHASE
BETA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		5 / 12 LEU B 321
GLY B 299
MET B 295
LEU B 302
ALA B 239
 None
 1.32A 5kc4E-5c2vB:
undetectable		 5kc4E-5c2vB:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		3 / 3 ALA A 429
GLN A 226
THR A 229
 None
 0.72A 5n0oA-5c2vA:
undetectable		 5n0oA-5c2vA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		5 / 12 ASN A 255
SER A 314
SER A 330
GLY A 312
GLN A 272
 None
 0.94A 5oj0A-5c2vA:
undetectable		 5oj0A-5c2vA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_A_CVIA608_0
(ACETYLCHOLINESTERASE)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		4 / 7 THR A 777
LEU A 776
VAL A 746
TYR A 750
 None
HEC  A 906 (-4.2A)
None
None
 1.11A 5ov9A-5c2vA:
undetectable		 5ov9A-5c2vA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB602_0
(ACETYLCHOLINESTERASE)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		4 / 8 THR A 777
LEU A 776
VAL A 746
TYR A 750
 None
HEC  A 906 (-4.2A)
None
None
 1.09A 5ov9B-5c2vA:
undetectable		 5ov9B-5c2vA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		4 / 8 TRP A 458
TYR A 554
ARG A 490
GLN A 557
 None
 1.38A 5tzoA-5c2vA:
undetectable		 5tzoA-5c2vA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		4 / 8 TRP A 458
TYR A 554
ARG A 490
GLN A 557
 None
 1.35A 5tzoB-5c2vA:
undetectable		 5tzoB-5c2vA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		4 / 8 TRP A 458
TYR A 554
ARG A 490
GLN A 557
 None
 1.33A 5tzoC-5c2vA:
undetectable		 5tzoC-5c2vA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		4 / 8 SER A 254
ARG A 518
VAL A 271
PHE A 206
 None
 1.17A 5uo7A-5c2vA:
undetectable
5uo7B-5c2vA:
undetectable		 5uo7A-5c2vA:
18.34
5uo7B-5c2vA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_1
(REGULATORY PROTEIN
TETR)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		5 / 8 GLY A 383
TRP A 335
GLN A  74
ASP A  71
ASP A 409
 None
None
None
None
CA  A 903 (-3.0A)
 1.42A 5vlmB-5c2vA:
undetectable		 5vlmB-5c2vA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_1
(REGULATORY PROTEIN
TETR)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		4 / 8 GLY A 383
TRP A 335
GLN A  74
ASP A  71
 None
 1.02A 5vlmD-5c2vA:
undetectable		 5vlmD-5c2vA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_1
(REGULATORY PROTEIN
TETR)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		4 / 7 GLY A 383
TRP A 335
GLN A  74
ASP A  71
 None
 1.15A 5vlmG-5c2vA:
undetectable		 5vlmG-5c2vA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		4 / 7 HIS A 453
ASP A 246
GLY A 235
ASN A 432
 None
 0.96A 5x7pA-5c2vA:
undetectable		 5x7pA-5c2vA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		4 / 5 HIS A 453
ASP A 246
GLY A 235
ASN A 432
 None
 0.99A 5x7pB-5c2vA:
undetectable		 5x7pB-5c2vA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		3 / 3 GLY A 585
VAL A 489
MET A 556
 CL  A 901 (-3.6A)
None
HEC  A 905 ( 3.8A)
 0.59A 5ycpA-5c2vA:
undetectable		 5ycpA-5c2vA:
7.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		3 / 3 LYS A 447
ASN A 432
SER A 234
 None
 1.25A 5yw0A-5c2vA:
undetectable		 5yw0A-5c2vA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5c2v HYDRAZINE SYNTHASE
BETA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		5 / 10 SER B 203
LEU B 190
ILE B 157
PRO B 178
SER B 174
 None
 1.40A 6dlzB-5c2vB:
undetectable
6dlzC-5c2vB:
undetectable		 6dlzB-5c2vB:
12.50
6dlzC-5c2vB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5c2v HYDRAZINE SYNTHASE
BETA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		5 / 11 ILE B 157
PRO B 178
SER B 174
SER B 203
LEU B 190
 None
 1.40A 6dlzA-5c2vB:
undetectable
6dlzD-5c2vB:
undetectable		 6dlzA-5c2vB:
12.50
6dlzD-5c2vB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5c2v HYDRAZINE SYNTHASE
BETA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		5 / 10 SER B 203
LEU B 190
ILE B 157
PRO B 178
SER B 174
 None
 1.41A 6dm1B-5c2vB:
undetectable
6dm1C-5c2vB:
undetectable		 6dm1B-5c2vB:
12.50
6dm1C-5c2vB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5c2v HYDRAZINE SYNTHASE
BETA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		5 / 11 ILE B 157
PRO B 178
SER B 174
SER B 203
LEU B 190
 None
 1.41A 6dm1A-5c2vB:
undetectable
6dm1D-5c2vB:
undetectable		 6dm1A-5c2vB:
12.50
6dm1D-5c2vB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5c2v HYDRAZINE SYNTHASE
BETA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		5 / 10 SER B 203
LEU B 190
ILE B 157
PRO B 178
SER B 174
 None
 1.40A 6dm2B-5c2vB:
undetectable
6dm2C-5c2vB:
undetectable		 6dm2B-5c2vB:
12.50
6dm2C-5c2vB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5c2v HYDRAZINE SYNTHASE
BETA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		5 / 10 ILE B 157
PRO B 178
SER B 174
SER B 203
LEU B 190
 None
 1.40A 6dm2A-5c2vB:
undetectable
6dm2D-5c2vB:
undetectable		 6dm2A-5c2vB:
12.50
6dm2D-5c2vB:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT
(Candidatus
Kuenenia
stuttgartiensis) 		4 / 5 ALA A 488
TYR A 535
GLN A 536
ILE A 491
 None
 1.40A 6f6sA-5c2vA:
undetectable
6f6sB-5c2vA:
undetectable		 6f6sA-5c2vA:
7.54
6f6sB-5c2vA:
6.80