SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5c30'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA6_0
(GRAMICIDIN A)		 5c30 RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		3 / 3 ALA A1002
VAL A 995
TRP A1005
 None
 0.95A 1gmkA-5c30A:
undetectable
1gmkB-5c30A:
undetectable		 1gmkA-5c30A:
5.56
1gmkB-5c30A:
5.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC6_0
(GRAMICIDIN A)		 5c30 RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		3 / 3 ALA A1002
VAL A 995
TRP A1005
 None
 0.98A 1gmkC-5c30A:
undetectable
1gmkD-5c30A:
undetectable		 1gmkC-5c30A:
5.56
1gmkD-5c30A:
5.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_B_RBFB502_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 5c30 RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		5 / 11 LEU A 932
HIS A 866
GLY A 926
SER A 925
LEU A 874
 None
 1.32A 1kyvA-5c30A:
undetectable
1kyvB-5c30A:
undetectable		 1kyvA-5c30A:
20.79
1kyvB-5c30A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_B_RBFB301_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 5c30 RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		5 / 12 LEU A 932
HIS A 866
GLY A 926
SER A 925
LEU A 874
 None
 1.32A 2a58A-5c30A:
undetectable
2a58B-5c30A:
undetectable		 2a58A-5c30A:
23.61
2a58B-5c30A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_E_RBFE304_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 5c30 RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		5 / 12 LEU A 932
HIS A 866
GLY A 926
SER A 925
LEU A 874
 None
 1.32A 2a58D-5c30A:
undetectable
2a58E-5c30A:
undetectable		 2a58D-5c30A:
23.61
2a58E-5c30A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA502_1
(CYTOCHROME P450 2B4)		 5c30 RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		5 / 12 LEU A 874
ILE A 870
LEU A 932
THR A 931
LEU A 933
 None
 1.07A 2bdmA-5c30A:
undetectable		 2bdmA-5c30A:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_F_D16F301_1
(THYMIDYLATE SYNTHASE)		 5c30 RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		5 / 11 HIS A 879
ILE A 878
LEU A 988
GLY A1004
TYR A1007
 None
 1.31A 4foxF-5c30A:
undetectable		 4foxF-5c30A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 5c30 RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		3 / 3 ALA A 946
ASN A 949
LEU A 950
 None
 0.19A 5i1oC-5c30A:
undetectable		 5i1oC-5c30A:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 5c30 RYANODINE RECEPTOR 1
(Oryctolagus
cuniculus) 		3 / 3 ALA A 946
ASN A 949
LEU A 950
 None
 0.25A 5i1pA-5c30A:
undetectable		 5i1pA-5c30A:
9.19