SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5c33'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y04_B_68HB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5c33 RYANODINE RECEPTOR 2
(Mus
musculus) 		5 / 12 VAL A 695
PHE A 789
SER A 654
SER A 793
PHE A 802
 None
 1.25A 2y04B-5c33A:
undetectable		 2y04B-5c33A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_C_BEZC264_0
(CARNITINYL-COA
DEHYDRATASE)		 5c33 RYANODINE RECEPTOR 2
(Mus
musculus) 		4 / 6 ALA A 825
ILE A 659
LEU A 661
ALA A 820
 None
 0.88A 3r9sC-5c33A:
undetectable		 3r9sC-5c33A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_A_GAIA407_0
(PROTEIN (ARGINASE))		 5c33 RYANODINE RECEPTOR 2
(Mus
musculus) 		4 / 6 ARG A 801
LEU A 677
MET A 678
ASP A 680
 None
 1.23A 4cevA-5c33A:
undetectable
4cevB-5c33A:
undetectable		 4cevA-5c33A:
21.25
4cevB-5c33A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_C_GAIC409_0
(PROTEIN (ARGINASE))		 5c33 RYANODINE RECEPTOR 2
(Mus
musculus) 		4 / 6 MET A 678
ASP A 680
ARG A 801
LEU A 677
 None
 1.25A 4cevA-5c33A:
undetectable
4cevC-5c33A:
undetectable		 4cevA-5c33A:
21.25
4cevC-5c33A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_D_GAID410_0
(PROTEIN (ARGINASE))		 5c33 RYANODINE RECEPTOR 2
(Mus
musculus) 		4 / 6 ARG A 801
LEU A 677
MET A 678
ASP A 680
 None
 1.28A 4cevD-5c33A:
undetectable
4cevE-5c33A:
undetectable		 4cevD-5c33A:
21.25
4cevE-5c33A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_F_GAIF411_0
(PROTEIN (ARGINASE))		 5c33 RYANODINE RECEPTOR 2
(Mus
musculus) 		4 / 6 ARG A 801
LEU A 677
MET A 678
ASP A 680
 None
 1.23A 4cevE-5c33A:
undetectable
4cevF-5c33A:
undetectable		 4cevE-5c33A:
21.25
4cevF-5c33A:
21.25