SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5c3j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NT6_A_DVAA6_0 (GRAMICIDIN C)	5c3j	CYTOCHROME B-LARGE SUBUNIT SUCCINATE DEHYDROGENASE [UBIQUINONE] CYTOCHROME B SMALL SUBUNIT, MITOCHONDRIAL (Ascaris suum; Ascaris suum)	3 / 3	ALA C 169 VAL C 171 TRP D 154	None None EPH D 201 (-3.7A)	0.84A	1nt6A-5c3jC: undetectable	1nt6A-5c3jC: 5.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NT6_B_DVAB6_0 (GRAMICIDIN C)	5c3j	CYTOCHROME B-LARGE SUBUNIT SUCCINATE DEHYDROGENASE [UBIQUINONE] CYTOCHROME B SMALL SUBUNIT, MITOCHONDRIAL (Ascaris suum; Ascaris suum)	3 / 3	ALA C 169 VAL C 171 TRP D 154	None None EPH D 201 (-3.7A)	0.84A	1nt6B-5c3jC: undetectable	1nt6B-5c3jC: 5.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IZQ_B_DVAB6_0 (GRAMICIDIN D)	5c3j	CYTOCHROME B-LARGE SUBUNIT SUCCINATE DEHYDROGENASE [UBIQUINONE] CYTOCHROME B SMALL SUBUNIT, MITOCHONDRIAL (Ascaris suum; Ascaris suum)	3 / 3	TRP D 154 ALA C 169 VAL C 171	EPH D 201 (-3.7A) None None	0.81A	2izqA-5c3jD: undetectable 2izqB-5c3jD: undetectable	2izqA-5c3jD: 7.28 2izqB-5c3jD: 7.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BCR_A_AZZA940_1 (GLYCOGEN PHOSPHORYLASE, MUSCLE FORM)	5c3j	SUCCINATE DEHYDROGENASE [UBIQUINONE] CYTOCHROME B SMALL SUBUNIT, MITOCHONDRIAL (Ascaris suum)	4 / 5	ASN D 140 PHE D 139 GLY D 135 TYR D 138	None	1.18A	3bcrA-5c3jD: 3.1	3bcrA-5c3jD: 11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L8L_A_DVAA6_0 (GRAMICIDIN D)	5c3j	CYTOCHROME B-LARGE SUBUNIT SUCCINATE DEHYDROGENASE [UBIQUINONE] CYTOCHROME B SMALL SUBUNIT, MITOCHONDRIAL (Ascaris suum; Ascaris suum)	3 / 3	ALA C 169 VAL C 171 TRP D 154	None None EPH D 201 (-3.7A)	0.80A	3l8lA-5c3jC: undetectable 3l8lB-5c3jC: undetectable	3l8lA-5c3jC: 10.20 3l8lB-5c3jC: 10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PS9_A_SAMA670_0 (TRNA 5-METHYLAMINOMETHYL- 2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC)	5c3j	CYTOCHROME B-LARGE SUBUNIT SUCCINATE DEHYDROGENASE [UBIQUINONE] CYTOCHROME B SMALL SUBUNIT, MITOCHONDRIAL (Ascaris suum; Ascaris suum)	5 / 12	GLY C 92 PHE C 103 ILE C 88 GLY C 90 PHE D 139	None	1.28A	3ps9A-5c3jC: undetectable	3ps9A-5c3jC: 13.15

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1NT6_A_DVAA6_0","GRAMICIDIN C","5c3j","CYTOCHROME B-LARGE SUBUNIT;SUCCINATE DEHYDROGENASE [UBIQUINONE] CYTOCHROME B SMALL SUBUNIT, MITOCHONDRIAL","Ascaris suum;Ascaris suum",3,"ALA C 169;VAL C 171;TRP D 154","None;None;EPH D 201 (-3.7A)","0.84A","1nt6A-5c3jC:undetectable","1nt6A-5c3jC:5.92"],["1NT6_B_DVAB6_0","GRAMICIDIN C","5c3j","CYTOCHROME B-LARGE SUBUNIT;SUCCINATE DEHYDROGENASE [UBIQUINONE] CYTOCHROME B SMALL SUBUNIT, MITOCHONDRIAL","Ascaris suum;Ascaris suum",3,"ALA C 169;VAL C 171;TRP D 154","None;None;EPH D 201 (-3.7A)","0.84A","1nt6B-5c3jC:undetectable","1nt6B-5c3jC:5.92"],["2IZQ_B_DVAB6_0","GRAMICIDIN D","5c3j","CYTOCHROME B-LARGE SUBUNIT;SUCCINATE DEHYDROGENASE [UBIQUINONE] CYTOCHROME B SMALL SUBUNIT, MITOCHONDRIAL","Ascaris suum;Ascaris suum",3,"TRP D 154;ALA C 169;VAL C 171","EPH D 201 (-3.7A);None;None","0.81A","2izqA-5c3jD:undetectable;2izqB-5c3jD:undetectable","2izqA-5c3jD:7.28;2izqB-5c3jD:7.28"],["3BCR_A_AZZA940_1","GLYCOGEN PHOSPHORYLASE, MUSCLE FORM","5c3j","SUCCINATE DEHYDROGENASE [UBIQUINONE] CYTOCHROME B SMALL SUBUNIT, MITOCHONDRIAL","Ascaris suum",4,"ASN D 140;PHE D 139;GLY D 135;TYR D 138","None","1.18A","3bcrA-5c3jD:3.1","3bcrA-5c3jD:11.01"],["3L8L_A_DVAA6_0","GRAMICIDIN D","5c3j","CYTOCHROME B-LARGE SUBUNIT;SUCCINATE DEHYDROGENASE [UBIQUINONE] CYTOCHROME B SMALL SUBUNIT, MITOCHONDRIAL","Ascaris suum;Ascaris suum",3,"ALA C 169;VAL C 171;TRP D 154","None;None;EPH D 201 (-3.7A)","0.80A","3l8lA-5c3jC:undetectable;3l8lB-5c3jC:undetectable","3l8lA-5c3jC:10.20;3l8lB-5c3jC:10.20"],["3PS9_A_SAMA670_0","TRNA 5-METHYLAMINOMETHYL-2-THIOURIDINE BIOSYNTHESIS BIFUNCTIONAL PROTEIN MNMC","5c3j","CYTOCHROME B-LARGE SUBUNIT;SUCCINATE DEHYDROGENASE [UBIQUINONE] CYTOCHROME B SMALL SUBUNIT, MITOCHONDRIAL","Ascaris suum;Ascaris suum",5,"GLY C  92;PHE C 103;ILE C  88;GLY C  90;PHE D 139","None","1.28A","3ps9A-5c3jC:undetectable","3ps9A-5c3jC:13.15"]]