SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5c4r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)		 5c4r PRECORRIN-6A
REDUCTASE
(Rhodobacter
capsulatus) 		3 / 3 ALA A 232
VAL A 237
TRP A 240
 None
 0.94A 1tkqA-5c4rA:
undetectable		 1tkqA-5c4rA:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_4
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 5c4r PRECORRIN-6A
REDUCTASE
(Rhodobacter
capsulatus) 		4 / 5 ALA A  21
ALA A  71
GLN A  19
VAL A 237
 None
 0.92A 2nyrB-5c4rA:
6.3		 2nyrB-5c4rA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_1
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)		 5c4r PRECORRIN-6A
REDUCTASE
(Rhodobacter
capsulatus) 		5 / 12 GLY A   9
ARG A  99
GLU A  98
ALA A  96
ARG A 228
 None
 1.17A 3jzjA-5c4rA:
undetectable		 3jzjA-5c4rA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_1
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 5c4r PRECORRIN-6A
REDUCTASE
(Rhodobacter
capsulatus) 		3 / 3 ARG A  99
ASN A 197
ASP A 108
 None
 0.87A 5gwxA-5c4rA:
4.0		 5gwxA-5c4rA:
22.22