SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5c5u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)		 5c5u PROLYL 4-HYDROXYLASE
(Paramecium
bursaria
Chlorella
virus
1) 		4 / 7 PHE A 188
GLY A 223
ILE A 233
TYR A 174
 None
UNX  A 302 ( 3.5A)
UNX  A 303 ( 4.4A)
None
 0.82A 11gsB-5c5uA:
undetectable		 11gsB-5c5uA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_B_ANWB99_0
(PROTEIN S100-A13)		 5c5u PROLYL 4-HYDROXYLASE
(Paramecium
bursaria
Chlorella
virus
1) 		4 / 8 ALA A 222
PHE A 188
THR A 190
LYS A 194
 None
 0.82A 2kotB-5c5uA:
undetectable		 2kotB-5c5uA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5c5u PROLYL 4-HYDROXYLASE
(Paramecium
bursaria
Chlorella
virus
1) 		4 / 8 PHE A 104
VAL A 140
ILE A 232
GLU A 108
 None
 1.08A 4a97G-5c5uA:
undetectable		 4a97G-5c5uA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_A_UEGA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 5c5u PROLYL 4-HYDROXYLASE
(Paramecium
bursaria
Chlorella
virus
1) 		5 / 11 GLY A 184
ASP A 187
ALA A 222
GLY A 223
HIS A 151
 None
None
None
UNX  A 302 ( 3.5A)
None
 0.98A 4c5lA-5c5uA:
undetectable		 4c5lA-5c5uA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_B_PXLB300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 5c5u PROLYL 4-HYDROXYLASE
(Paramecium
bursaria
Chlorella
virus
1) 		5 / 9 GLY A 184
ASP A 187
ALA A 222
GLY A 223
HIS A 151
 None
None
None
UNX  A 302 ( 3.5A)
None
 0.97A 4c5lB-5c5uA:
undetectable		 4c5lB-5c5uA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_C_UEGC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 5c5u PROLYL 4-HYDROXYLASE
(Paramecium
bursaria
Chlorella
virus
1) 		5 / 10 GLY A 184
ASP A 187
ALA A 222
GLY A 223
HIS A 151
 None
None
None
UNX  A 302 ( 3.5A)
None
 1.06A 4c5lC-5c5uA:
undetectable		 4c5lC-5c5uA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 5c5u PROLYL 4-HYDROXYLASE
(Paramecium
bursaria
Chlorella
virus
1) 		5 / 10 GLY A 184
ASP A 187
ALA A 222
GLY A 223
HIS A 151
 None
None
None
UNX  A 302 ( 3.5A)
None
 0.96A 4c5lD-5c5uA:
undetectable		 4c5lD-5c5uA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_B_PXLB300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 5c5u PROLYL 4-HYDROXYLASE
(Paramecium
bursaria
Chlorella
virus
1) 		5 / 10 GLY A 184
ASP A 187
ALA A 222
GLY A 223
HIS A 151
 None
None
None
UNX  A 302 ( 3.5A)
None
 0.95A 4c5nB-5c5uA:
undetectable		 4c5nB-5c5uA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 5c5u PROLYL 4-HYDROXYLASE
(Paramecium
bursaria
Chlorella
virus
1) 		5 / 10 GLY A 184
ASP A 187
ALA A 222
GLY A 223
HIS A 151
 None
None
None
UNX  A 302 ( 3.5A)
None
 0.97A 4c5nD-5c5uA:
undetectable		 4c5nD-5c5uA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA301_1
(CHITOSANASE)		 5c5u PROLYL 4-HYDROXYLASE
(Paramecium
bursaria
Chlorella
virus
1) 		3 / 3 TYR A 216
GLY A  45
PRO A  44
 None
 0.72A 4qwpA-5c5uA:
undetectable		 4qwpA-5c5uA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_B_ACTB804_0
(UNCHARACTERIZED
PROTEIN)		 5c5u PROLYL 4-HYDROXYLASE
(Paramecium
bursaria
Chlorella
virus
1) 		4 / 4 HIS A 109
VAL A 140
LEU A  67
ALA A  70
 None
 1.43A 6d8pB-5c5uA:
undetectable		 6d8pB-5c5uA:
14.61