SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5c5z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_A_BEZA11_0
(CES1 PROTEIN)		 5c5z GLUTAMYL-TRNA
AMIDOTRANSFERASE
(Escherichia
coli) 		4 / 4 LEU A  12
SER A  79
LEU A  68
LEU A   6
 None
 1.02A 1yajA-5c5zA:
undetectable		 1yajA-5c5zA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_D_BEZD2385_0
(CES1 PROTEIN)		 5c5z GLUTAMYL-TRNA
AMIDOTRANSFERASE
(Escherichia
coli) 		4 / 5 LEU A  12
SER A  79
LEU A  68
LEU A   6
 None
 1.03A 1yajD-5c5zA:
undetectable		 1yajD-5c5zA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_2
(PHOSPHOLIPASE A2)		 5c5z GLUTAMYL-TRNA
AMIDOTRANSFERASE
(Escherichia
coli) 		5 / 9 VAL A  63
VAL A   8
GLY A  10
PRO A  49
GLY A 117
 None
 1.00A 3bjwG-5c5zA:
undetectable		 3bjwG-5c5zA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_B_BEZB261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 5c5z GLUTAMYL-TRNA
AMIDOTRANSFERASE
(Escherichia
coli) 		4 / 8 HIS A 127
TRP A  66
PHE A  29
ARG A 120
 None
 1.32A 3ccfB-5c5zA:
undetectable		 3ccfB-5c5zA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 5c5z GLUTAMYL-TRNA
AMIDOTRANSFERASE
(Escherichia
coli) 		3 / 3 HIS A 127
GLU A  64
ASN A  19
 None
 0.98A 4bupB-5c5zA:
undetectable		 4bupB-5c5zA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5c5z GLUTAMYL-TRNA
AMIDOTRANSFERASE
(Escherichia
coli) 		4 / 6 LEU A 101
ASN A   9
LEU A  41
GLU A 112
 None
 1.21A 4nc3A-5c5zA:
undetectable		 4nc3A-5c5zA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW2_A_ACTA511_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 5c5z GLUTAMYL-TRNA
AMIDOTRANSFERASE
(Escherichia
coli) 		3 / 3 ARG A 111
ILE A 113
SER A  43
 None
 0.84A 5zw2A-5c5zA:
undetectable		 5zw2A-5c5zA:
18.97