SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5c69'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_GLYA1292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5c69 FUSION GLYCOPROTEIN
F0,FIBRITIN
(Enterobacteria
phage
Ox2;
Human
orthopneumovirus) 		4 / 8 SER A 260
SER A 221
TYR A 272
PHE A 210
 None
 1.22A 1eqbA-5c69A:
undetectable
1eqbB-5c69A:
undetectable		 1eqbA-5c69A:
21.70
1eqbB-5c69A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_GLYB2292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5c69 FUSION GLYCOPROTEIN
F0,FIBRITIN
(Enterobacteria
phage
Ox2;
Human
orthopneumovirus) 		4 / 8 TYR A 272
PHE A 210
SER A 260
SER A 221
 None
 1.25A 1eqbA-5c69A:
undetectable
1eqbB-5c69A:
undetectable		 1eqbA-5c69A:
21.70
1eqbB-5c69A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_GLYC3292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5c69 FUSION GLYCOPROTEIN
F0,FIBRITIN
(Enterobacteria
phage
Ox2;
Human
orthopneumovirus) 		4 / 8 SER A 260
SER A 221
TYR A 272
PHE A 210
 None
 1.23A 1eqbC-5c69A:
undetectable
1eqbD-5c69A:
undetectable		 1eqbC-5c69A:
21.70
1eqbD-5c69A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_GLYD4292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5c69 FUSION GLYCOPROTEIN
F0,FIBRITIN
(Enterobacteria
phage
Ox2;
Human
orthopneumovirus) 		4 / 8 TYR A 272
PHE A 210
SER A 260
SER A 221
 None
 1.24A 1eqbC-5c69A:
undetectable
1eqbD-5c69A:
undetectable		 1eqbC-5c69A:
21.70
1eqbD-5c69A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5c69 FUSION GLYCOPROTEIN
F0,FIBRITIN
(Enterobacteria
phage
Ox2;
Human
orthopneumovirus) 		4 / 7 GLY A 280
THR A 342
THR A  50
SER A 323
 None
 0.90A 1gtfL-5c69A:
undetectable
1gtfM-5c69A:
undetectable		 1gtfL-5c69A:
11.00
1gtfM-5c69A:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5c69 FUSION GLYCOPROTEIN
F0,FIBRITIN
(Enterobacteria
phage
Ox2;
Human
orthopneumovirus) 		4 / 7 SER A 323
GLY A 280
THR A 342
THR A  50
 None
 0.79A 1gtnC-5c69A:
0.8
1gtnD-5c69A:
undetectable		 1gtnC-5c69A:
11.00
1gtnD-5c69A:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5c69 FUSION GLYCOPROTEIN
F0,FIBRITIN
(Enterobacteria
phage
Ox2;
Human
orthopneumovirus) 		4 / 6 SER A 323
GLY A 280
THR A 342
THR A  50
 None
 0.86A 1gtnD-5c69A:
undetectable
1gtnE-5c69A:
undetectable		 1gtnD-5c69A:
11.00
1gtnE-5c69A:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5c69 FUSION GLYCOPROTEIN
F0,FIBRITIN
(Enterobacteria
phage
Ox2;
Human
orthopneumovirus) 		4 / 7 SER A 323
GLY A 280
THR A 342
THR A  50
 None
 0.89A 1gtnF-5c69A:
undetectable
1gtnG-5c69A:
undetectable		 1gtnF-5c69A:
11.00
1gtnG-5c69A:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5c69 FUSION GLYCOPROTEIN
F0,FIBRITIN
(Enterobacteria
phage
Ox2;
Human
orthopneumovirus) 		4 / 7 SER A 323
GLY A 280
THR A 342
THR A  50
 None
 0.87A 1gtnJ-5c69A:
undetectable
1gtnK-5c69A:
undetectable		 1gtnJ-5c69A:
11.00
1gtnK-5c69A:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1122_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5c69 FUSION GLYCOPROTEIN
F0,FIBRITIN
(Enterobacteria
phage
Ox2;
Human
orthopneumovirus) 		4 / 7 SER A  55
VAL A 274
SER A 163
LYS A 149
 None
 1.07A 2j9cA-5c69A:
undetectable
2j9cB-5c69A:
undetectable
2j9cC-5c69A:
undetectable		 2j9cA-5c69A:
12.63
2j9cB-5c69A:
12.63
2j9cC-5c69A:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1122_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5c69 FUSION GLYCOPROTEIN
F0,FIBRITIN
(Enterobacteria
phage
Ox2;
Human
orthopneumovirus) 		4 / 7 SER A 163
LYS A 149
VAL A 165
SER A  55
 None
 1.15A 2j9cA-5c69A:
undetectable
2j9cB-5c69A:
undetectable
2j9cC-5c69A:
undetectable		 2j9cA-5c69A:
12.63
2j9cB-5c69A:
12.63
2j9cC-5c69A:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_B_PNTB901_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 5c69 FUSION GLYCOPROTEIN
F0,FIBRITIN
(Enterobacteria
phage
Ox2;
Human
orthopneumovirus) 		5 / 12 THR A 381
TYR A 414
ASP A 413
GLY A 411
TYR A 390
 None
 1.35A 3hiiB-5c69A:
undetectable		 3hiiB-5c69A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5c69 FUSION GLYCOPROTEIN
F0,FIBRITIN
(Enterobacteria
phage
Ox2;
Human
orthopneumovirus) 		4 / 4 ASN A 410
GLY A 411
ASP A 452
ASP A 374
 None
 1.42A 4n49A-5c69A:
undetectable		 4n49A-5c69A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5c69 FUSION GLYCOPROTEIN
F0,FIBRITIN
(Enterobacteria
phage
Ox2;
Human
orthopneumovirus) 		4 / 6 ALA A 271
THR A  58
VAL A 269
VAL A 152
 None
 1.00A 5eclA-5c69A:
undetectable		 5eclA-5c69A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5c69 FUSION GLYCOPROTEIN
F0,FIBRITIN
(Enterobacteria
phage
Ox2;
Human
orthopneumovirus) 		4 / 8 SER A 323
GLY A 280
THR A 342
THR A  50
 None
 0.87A 5eevL-5c69A:
undetectable
5eevV-5c69A:
undetectable		 5eevL-5c69A:
11.00
5eevV-5c69A:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5c69 FUSION GLYCOPROTEIN
F0,FIBRITIN
(Enterobacteria
phage
Ox2;
Human
orthopneumovirus) 		4 / 8 SER A 323
GLY A 280
THR A 342
THR A  50
 None
 0.87A 5eewL-5c69A:
undetectable
5eewV-5c69A:
undetectable		 5eewL-5c69A:
11.00
5eewV-5c69A:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5c69 FUSION GLYCOPROTEIN
F0,FIBRITIN
(Enterobacteria
phage
Ox2;
Human
orthopneumovirus) 		4 / 8 SER A 323
GLY A 280
THR A 342
THR A  50
 None
 0.87A 5eezL-5c69A:
undetectable
5eezV-5c69A:
undetectable		 5eezL-5c69A:
11.00
5eezV-5c69A:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5c69 FUSION GLYCOPROTEIN
F0,FIBRITIN
(Enterobacteria
phage
Ox2;
Human
orthopneumovirus) 		4 / 8 SER A 323
GLY A 280
THR A 342
THR A  50
 None
 0.87A 5ef1L-5c69A:
undetectable
5ef1V-5c69A:
undetectable		 5ef1L-5c69A:
11.00
5ef1V-5c69A:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5c69 FUSION GLYCOPROTEIN
F0,FIBRITIN
(Enterobacteria
phage
Ox2;
Human
orthopneumovirus) 		4 / 8 SER A 323
GLY A 280
THR A 342
THR A  50
 None
 0.87A 5ef2L-5c69A:
undetectable
5ef2V-5c69A:
undetectable		 5ef2L-5c69A:
11.00
5ef2V-5c69A:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5c69 FUSION GLYCOPROTEIN
F0,FIBRITIN
(Enterobacteria
phage
Ox2;
Human
orthopneumovirus) 		4 / 8 SER A 323
GLY A 280
THR A 342
THR A  50
 None
 0.87A 5ef3L-5c69A:
undetectable
5ef3V-5c69A:
undetectable		 5ef3L-5c69A:
11.00
5ef3V-5c69A:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 5c69 FUSION GLYCOPROTEIN
F0,FIBRITIN
(Enterobacteria
phage
Ox2;
Human
orthopneumovirus) 		5 / 12 VAL A 281
THR A  50
VAL A 322
PHE A 325
VAL A 338
 None
 1.15A 6a94B-5c69A:
undetectable		 6a94B-5c69A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_E_GBME2001_1
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 5c69 FUSION GLYCOPROTEIN
F0,FIBRITIN
(Enterobacteria
phage
Ox2;
Human
orthopneumovirus) 		5 / 12 ARG A 255
ILE A 206
MET A 262
LEU A 233
ARG A 202
 None
 1.35A 6baaE-5c69A:
0.0		 6baaE-5c69A:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_F_GBMF2001_1
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 5c69 FUSION GLYCOPROTEIN
F0,FIBRITIN
(Enterobacteria
phage
Ox2;
Human
orthopneumovirus) 		5 / 12 ARG A 255
ILE A 206
MET A 262
LEU A 233
ARG A 202
 None
 1.35A 6baaF-5c69A:
0.0		 6baaF-5c69A:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_G_GBMG2001_1
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 5c69 FUSION GLYCOPROTEIN
F0,FIBRITIN
(Enterobacteria
phage
Ox2;
Human
orthopneumovirus) 		5 / 12 ARG A 255
ILE A 206
MET A 262
LEU A 233
ARG A 202
 None
 1.35A 6baaG-5c69A:
0.0		 6baaG-5c69A:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_H_GBMH2001_1
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 5c69 FUSION GLYCOPROTEIN
F0,FIBRITIN
(Enterobacteria
phage
Ox2;
Human
orthopneumovirus) 		5 / 12 ARG A 255
ILE A 206
MET A 262
LEU A 233
ARG A 202
 None
 1.35A 6baaH-5c69A:
0.0		 6baaH-5c69A:
16.31