SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5c6f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1200_1
(SERUM ALBUMIN)		 5c6f BACTERIAL NON-HEME
FERRITIN
(Helicobacter
pylori) 		4 / 4 LEU A  43
ILE A 137
ILE A 161
ALA A 162
 None
 0.89A 2i30A-5c6fA:
undetectable		 2i30A-5c6fA:
13.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_B_NIOB5661_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 5c6f BACTERIAL NON-HEME
FERRITIN
(Helicobacter
pylori) 		4 / 8 ILE A  86
ALA A  90
PHE A 134
LEU A  23
 None
 0.90A 3hrdA-5c6fA:
undetectable
3hrdB-5c6fA:
undetectable		 3hrdA-5c6fA:
16.00
3hrdB-5c6fA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VN2_A_TLSA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5c6f BACTERIAL NON-HEME
FERRITIN
(Helicobacter
pylori) 		5 / 12 SER A 100
ILE A 101
TYR A 123
LEU A 120
LEU A  61
 None
None
IMD  A 204 (-3.7A)
None
None
 1.05A 3vn2A-5c6fA:
undetectable		 3vn2A-5c6fA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_E_377E401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5c6f BACTERIAL NON-HEME
FERRITIN
(Helicobacter
pylori) 		4 / 6 ASN A 102
GLU A  17
TYR A 123
LEU A 120
 None
FE  A 203 ( 4.7A)
IMD  A 204 (-3.7A)
None
 1.30A 4twdD-5c6fA:
4.2
4twdE-5c6fA:
3.9		 4twdD-5c6fA:
17.63
4twdE-5c6fA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_J_377J401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5c6f BACTERIAL NON-HEME
FERRITIN
(Helicobacter
pylori) 		4 / 6 ASN A 102
GLU A  17
TYR A 123
LEU A 120
 None
FE  A 203 ( 4.7A)
IMD  A 204 (-3.7A)
None
 1.24A 4twdI-5c6fA:
undetectable
4twdJ-5c6fA:
undetectable		 4twdI-5c6fA:
17.63
4twdJ-5c6fA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_E_ASCE1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 5c6f BACTERIAL NON-HEME
FERRITIN
(Helicobacter
pylori) 		4 / 7 HIS A 114
HIS A 107
ILE A 109
VAL A 105
 None
 1.27A 5kkzC-5c6fA:
undetectable
5kkzE-5c6fA:
undetectable		 5kkzC-5c6fA:
22.55
5kkzE-5c6fA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_K_ASCK1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 5c6f BACTERIAL NON-HEME
FERRITIN
(Helicobacter
pylori) 		4 / 7 HIS A 107
ILE A 109
VAL A 105
HIS A 114
 None
 1.26A 5kkzK-5c6fA:
3.0
5kkzQ-5c6fA:
undetectable		 5kkzK-5c6fA:
17.39
5kkzQ-5c6fA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_O_ASCO1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 5c6f BACTERIAL NON-HEME
FERRITIN
(Helicobacter
pylori) 		4 / 7 HIS A 114
HIS A 107
ILE A 109
VAL A 105
 None
 1.30A 5kkzM-5c6fA:
undetectable
5kkzO-5c6fA:
2.0		 5kkzM-5c6fA:
22.55
5kkzO-5c6fA:
17.39