SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5c6w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA6_0
(GRAMICIDIN A)		 5c6w PROTEIN
IGHV1-69-2,IG LAMBDA
CHAIN V-II REGION
NIG-84
(Homo
sapiens) 		3 / 3 ALA H 113
VAL H1035
TRP H1034
 None
 0.99A 1c4dA-5c6wH:
undetectable
1c4dB-5c6wH:
undetectable		 1c4dA-5c6wH:
8.51
1c4dB-5c6wH:
8.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_B_SAMB202_0
(UPF0066 PROTEIN
AF_0241)		 5c6w PROTEIN
IGHV1-69-2,IG LAMBDA
CHAIN V-II REGION
NIG-84
(Homo
sapiens) 		5 / 12 ASP H1087
LYS H1106
PRO H1007
GLY H1102
LEU H1004
 None
None
PEG  H1224 ( 4.1A)
None
None
 1.35A 2nv4B-5c6wH:
undetectable		 2nv4B-5c6wH:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OLD_B_IPHB2001_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 5c6w PROTEIN
IGHV1-69-2,IG LAMBDA
CHAIN V-II REGION
NIG-84
(Homo
sapiens) 		4 / 7 TYR H  95
TYR H1038
PRO H1046
TYR H1089
 None
 0.65A 2oldA-5c6wH:
14.2
2oldB-5c6wH:
14.1		 2oldA-5c6wH:
28.96
2oldB-5c6wH:
28.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OLD_B_IPHB2001_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 5c6w PROTEIN
IGHV1-69-2,IG LAMBDA
CHAIN V-II REGION
NIG-84
(Homo
sapiens) 		4 / 7 TYR H1038
PRO H1046
TYR H1089
TYR H  95
 None
 0.60A 2oldA-5c6wH:
14.2
2oldB-5c6wH:
14.1		 2oldA-5c6wH:
28.96
2oldB-5c6wH:
28.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5c6w PROTEIN
IGHV1-69-2,IG LAMBDA
CHAIN V-II REGION
NIG-84
(Homo
sapiens) 		5 / 12 ALA H1012
SER H1011
VAL H1107
ILE H1020
SER H1074
 None
 1.07A 4c49A-5c6wH:
undetectable		 4c49A-5c6wH:
20.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CJK_B_ACTB302_0
(IMMUNOGLOBULIN FAB
HEAVY CHAIN)		 5c6w PROTEIN
IGHV1-69-2,IG LAMBDA
CHAIN V-II REGION
NIG-84
(Homo
sapiens) 		3 / 3 TYR H  60
GLY H  66
THR H  69
 None
 0.17A 6cjkB-5c6wH:
18.8		 6cjkB-5c6wH:
33.33