SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5c7i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_G_CCSG149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 5c7i GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Mus
musculus) 		4 / 7 ASN O 420
TYR O 424
ASN O 259
TYR O 418
 None
 0.95A 1dssG-5c7iO:
52.7		 1dssG-5c7iO:
68.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_G_CCSG149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 5c7i GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Mus
musculus) 		7 / 7 SER O 255
THR O 257
ASN O 259
CYH O 260
TYR O 418
ASN O 420
TYR O 424
 None
 0.23A 1dssG-5c7iO:
52.7		 1dssG-5c7iO:
68.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_R_CCSR149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 5c7i GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Mus
musculus) 		4 / 8 ASN O 420
TYR O 424
ASN O 259
TYR O 418
 None
 0.94A 1dssR-5c7iO:
52.6		 1dssR-5c7iO:
68.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_R_CCSR149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 5c7i GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Mus
musculus) 		8 / 8 SER O 255
THR O 257
ASN O 259
CYH O 260
HIS O 283
TYR O 418
ASN O 420
TYR O 424
 None
 0.41A 1dssR-5c7iO:
52.6		 1dssR-5c7iO:
68.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_A_ACTA1107_0
(C5A PEPTIDASE)		 5c7i GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Mus
musculus) 		4 / 5 LEU O 353
GLY O 273
HIS O 269
ILE O 268
 None
 0.72A 1xf1A-5c7iO:
2.9		 1xf1A-5c7iO:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_B_ACTB1108_0
(C5A PEPTIDASE)		 5c7i GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Mus
musculus) 		4 / 6 LEU O 353
GLY O 273
HIS O 269
ILE O 268
 None
 0.67A 1xf1B-5c7iO:
2.5		 1xf1B-5c7iO:
16.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DMT_C_CCSC166_0
(GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
GLYCOSOMAL)		 5c7i GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Mus
musculus) 		4 / 8 ASN O 420
TYR O 424
ASN O 259
TYR O 418
 None
 0.97A 3dmtC-5c7iO:
48.6		 3dmtC-5c7iO:
51.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DMT_C_CCSC166_0
(GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
GLYCOSOMAL)		 5c7i GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Mus
musculus) 		8 / 8 SER O 255
THR O 257
ASN O 259
CYH O 260
HIS O 283
TYR O 418
ASN O 420
TYR O 424
 None
 0.35A 3dmtC-5c7iO:
48.6		 3dmtC-5c7iO:
51.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5c7i GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Mus
musculus) 		5 / 10 CYH O 201
ILE O 118
VAL O 136
GLY O 111
VAL O 125
 None
 1.19A 3em0A-5c7iO:
undetectable		 3em0A-5c7iO:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_B_STIB4_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 5c7i GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Mus
musculus) 		4 / 5 VAL O 110
ILE O 177
MET O 149
ARG O 433
 None
 1.39A 3pyyB-5c7iO:
undetectable		 3pyyB-5c7iO:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		 5c7i GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Mus
musculus) 		4 / 6 THR O 202
ASN O 113
ASP O 138
ILE O 141
 None
 1.45A 3w9tB-5c7iO:
undetectable		 3w9tB-5c7iO:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 5c7i GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Mus
musculus) 		3 / 3 ASN O 343
ASP O 419
ASN O 420
 None
 0.75A 4agaA-5c7iO:
undetectable		 4agaA-5c7iO:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_G_377G401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5c7i GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Mus
musculus) 		4 / 6 TYR O 243
GLU O 439
TYR O 197
LEU O 432
 None
 1.36A 4twdF-5c7iO:
undetectable
4twdG-5c7iO:
undetectable		 4twdF-5c7iO:
20.29
4twdG-5c7iO:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERS_A_ACTA803_0
(GEPHYRIN)		 5c7i GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Mus
musculus) 		3 / 3 THR O 258
ALA O 254
ASN O 259
 None
 0.55A 5ersA-5c7iO:
undetectable		 5ersA-5c7iO:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 5c7i GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Mus
musculus) 		4 / 7 VAL O 412
LEU O 414
ALA O 406
LEU O 353
 None
 0.56A 5jq7A-5c7iO:
undetectable		 5jq7A-5c7iO:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM2_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 5c7i GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Mus
musculus) 		5 / 9 VAL O 136
LEU O 123
PHE O 150
VAL O 172
ILE O 177
 None
 1.21A 5om2A-5c7iO:
undetectable
5om2B-5c7iO:
undetectable		 5om2A-5c7iO:
12.62
5om2B-5c7iO:
9.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 5c7i GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Mus
musculus) 		4 / 6 PHE O 337
VAL O 282
ALA O 336
THR O 257
 None
 1.06A 5t7bA-5c7iO:
4.1		 5t7bA-5c7iO:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_2
(CYTOCHROME P450 2C9)		 5c7i GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Mus
musculus) 		3 / 3 LEU O 108
VAL O 429
ASP O 430
 None
 0.59A 5x23A-5c7iO:
undetectable		 5x23A-5c7iO:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC605_0
(ALPHA-AMYLASE)		 5c7i GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Mus
musculus) 		4 / 8 GLY O 119
ILE O 118
ASP O 153
HIS O 156
 None
 0.95A 6ag0C-5c7iO:
undetectable		 6ag0C-5c7iO:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5c7i GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Mus
musculus) 		4 / 8 ILE O 208
PRO O 232
ILE O 215
TYR O 197
 None
 0.93A 6cduG-5c7iO:
undetectable
6cduH-5c7iO:
undetectable		 6cduG-5c7iO:
21.57
6cduH-5c7iO:
21.57