SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5c7o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_G_CCSG149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 5c7o GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Homo
sapiens) 		4 / 7 ASN O 388
TYR O 392
ASN O 227
TYR O 386
 NAD  O 501 (-3.9A)
NAD  O 501 (-2.7A)
OCS  O 224 ( 4.8A)
OCS  O 224 ( 4.0A)
 0.93A 1dssG-5c7oO:
53.6		 1dssG-5c7oO:
66.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_G_CCSG149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 5c7o GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Homo
sapiens) 		7 / 7 SER O 223
THR O 225
ASN O 227
CYH O 228
TYR O 386
ASN O 388
TYR O 392
 OCS  O 224 ( 3.4A)
OCS  O 224 ( 4.2A)
OCS  O 224 ( 4.8A)
None
OCS  O 224 ( 4.0A)
NAD  O 501 (-3.9A)
NAD  O 501 (-2.7A)
 0.12A 1dssG-5c7oO:
53.6		 1dssG-5c7oO:
66.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_R_CCSR149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 5c7o GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Homo
sapiens) 		4 / 8 ASN O 388
TYR O 392
ASN O 227
TYR O 386
 NAD  O 501 (-3.9A)
NAD  O 501 (-2.7A)
OCS  O 224 ( 4.8A)
OCS  O 224 ( 4.0A)
 0.92A 1dssR-5c7oO:
53.5		 1dssR-5c7oO:
66.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_R_CCSR149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 5c7o GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Homo
sapiens) 		8 / 8 SER O 223
THR O 225
ASN O 227
CYH O 228
HIS O 251
TYR O 386
ASN O 388
TYR O 392
 OCS  O 224 ( 3.4A)
OCS  O 224 ( 4.2A)
OCS  O 224 ( 4.8A)
None
OCS  O 224 ( 3.9A)
OCS  O 224 ( 4.0A)
NAD  O 501 (-3.9A)
NAD  O 501 (-2.7A)
 0.31A 1dssR-5c7oO:
53.5		 1dssR-5c7oO:
66.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_A_ACTA1107_0
(C5A PEPTIDASE)		 5c7o GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Homo
sapiens) 		4 / 5 LEU O 321
GLY O 241
HIS O 237
ILE O 236
 None
 0.70A 1xf1A-5c7oO:
2.9		 1xf1A-5c7oO:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_B_ACTB1108_0
(C5A PEPTIDASE)		 5c7o GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Homo
sapiens) 		4 / 6 LEU O 321
GLY O 241
HIS O 237
ILE O 236
 None
 0.67A 1xf1B-5c7oO:
2.3		 1xf1B-5c7oO:
15.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DMT_C_CCSC166_0
(GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
GLYCOSOMAL)		 5c7o GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Homo
sapiens) 		4 / 8 ASN O 388
TYR O 392
ASN O 227
TYR O 386
 NAD  O 501 (-3.9A)
NAD  O 501 (-2.7A)
OCS  O 224 ( 4.8A)
OCS  O 224 ( 4.0A)
 0.94A 3dmtC-5c7oO:
49.8		 3dmtC-5c7oO:
52.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DMT_C_CCSC166_0
(GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
GLYCOSOMAL)		 5c7o GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Homo
sapiens) 		8 / 8 SER O 223
THR O 225
ASN O 227
CYH O 228
HIS O 251
TYR O 386
ASN O 388
TYR O 392
 OCS  O 224 ( 3.4A)
OCS  O 224 ( 4.2A)
OCS  O 224 ( 4.8A)
None
OCS  O 224 ( 3.9A)
OCS  O 224 ( 4.0A)
NAD  O 501 (-3.9A)
NAD  O 501 (-2.7A)
 0.24A 3dmtC-5c7oO:
49.8		 3dmtC-5c7oO:
52.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_B_STIB4_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 5c7o GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Homo
sapiens) 		4 / 5 VAL O  78
ILE O 145
MET O 117
ARG O 401
 None
 1.40A 3pyyB-5c7oO:
undetectable		 3pyyB-5c7oO:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		 5c7o GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Homo
sapiens) 		4 / 6 THR O 170
ASN O  81
ASP O 106
ILE O 109
 NAD  O 501 (-4.1A)
NAD  O 501 (-2.9A)
NAD  O 501 (-2.4A)
None
 1.41A 3w9tB-5c7oO:
undetectable		 3w9tB-5c7oO:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_A_SAMA1001_0
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 5c7o GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Homo
sapiens) 		5 / 12 GLY O 125
TYR O 120
TYR O 127
GLU O  96
TYR O 390
 None
 1.43A 4ymgA-5c7oO:
undetectable		 4ymgA-5c7oO:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 5c7o GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Homo
sapiens) 		4 / 6 ASP O 270
ALA O 274
THR O 256
THR O 254
 None
None
SO4  O 502 (-3.0A)
SO4  O 502 (-3.0A)
 1.50A 4z4cA-5c7oO:
4.1		 4z4cA-5c7oO:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERS_A_ACTA803_0
(GEPHYRIN)		 5c7o GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Homo
sapiens) 		3 / 3 THR O 226
ALA O 222
ASN O 227
 None
None
OCS  O 224 ( 4.8A)
 0.55A 5ersA-5c7oO:
2.3		 5ersA-5c7oO:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_B_SAMB301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5c7o GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Homo
sapiens) 		5 / 12 ALA O 347
ASP O 398
GLY O 391
SER O 393
TYR O 390
 None
 1.34A 5hfjB-5c7oO:
2.1		 5hfjB-5c7oO:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_C_FUAC1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 5c7o GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Homo
sapiens) 		3 / 3 VAL O 104
HIS O 143
VAL O 140
 None
 0.71A 5jmnC-5c7oO:
undetectable		 5jmnC-5c7oO:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 5c7o GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Homo
sapiens) 		4 / 7 VAL O 380
LEU O 382
ALA O 374
LEU O 321
 None
 0.59A 5jq7A-5c7oO:
undetectable		 5jq7A-5c7oO:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 5c7o GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Homo
sapiens) 		4 / 6 PHE O 305
VAL O 250
ALA O 304
THR O 225
 None
None
None
OCS  O 224 ( 4.2A)
 1.01A 5t7bA-5c7oO:
2.8		 5t7bA-5c7oO:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_B_PA1B204_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)		 5c7o GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Homo
sapiens) 		3 / 3 GLY O 214
ASN O 212
ARG O 406
 None
 0.78A 5w7bD-5c7oO:
undetectable		 5w7bD-5c7oO:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_2
(CYTOCHROME P450 2C9)		 5c7o GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Homo
sapiens) 		3 / 3 LEU O  76
VAL O 397
ASP O 398
 None
 0.55A 5x23A-5c7oO:
undetectable		 5x23A-5c7oO:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC605_0
(ALPHA-AMYLASE)		 5c7o GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Homo
sapiens) 		4 / 8 GLY O  87
ILE O  86
ASP O 121
HIS O 124
 None
NAD  O 501 (-4.1A)
None
None
 1.00A 6ag0C-5c7oO:
undetectable		 6ag0C-5c7oO:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 5c7o GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Homo
sapiens) 		3 / 3 ASN O  81
PRO O 153
GLN O 155
 NAD  O 501 (-2.9A)
None
None
 0.80A 6jnhA-5c7oO:
undetectable		 6jnhA-5c7oO:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 5c7o GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
TESTIS-SPECIFIC
(Homo
sapiens) 		3 / 3 ASN O  81
PRO O 153
GLN O 155
 NAD  O 501 (-2.9A)
None
None
 0.80A 6jogA-5c7oO:
3.0		 6jogA-5c7oO:
18.75