SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5c7q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GXS_A_BEZA601_0
(P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
A
P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
B)		 5c7q NUDF PROTEIN
(Bdellovibrio
bacteriovorus) 		4 / 7 PRO A 112
SER A 117
HIS A  42
ALA A  45
 None
None
GOL  A 205 (-4.3A)
GOL  A 207 (-3.5A)
 1.00A 1gxsA-5c7qA:
undetectable
1gxsB-5c7qA:
undetectable		 1gxsA-5c7qA:
24.19
1gxsB-5c7qA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA888_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))		 5c7q NUDF PROTEIN
(Bdellovibrio
bacteriovorus) 		4 / 5 PRO A  50
MET A  48
ALA A  76
GLU A  96
 None
None
GOL  A 207 ( 3.9A)
None
 1.18A 1qhsA-5c7qA:
undetectable		 1qhsA-5c7qA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR3_A_GLYA701_0
(GLYCINE--TRNA LIGASE)		 5c7q NUDF PROTEIN
(Bdellovibrio
bacteriovorus) 		4 / 6 GLU A 140
ARG A  64
GLU A  96
GLU A  92
 None
SO4  A 201 ( 3.1A)
None
None
 1.48A 4kr3A-5c7qA:
undetectable		 4kr3A-5c7qA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA302_1
(CHITOSANASE)		 5c7q NUDF PROTEIN
(Bdellovibrio
bacteriovorus) 		4 / 5 THR A  11
THR A   8
ASP A  25
TYR A  39
 None
 1.14A 4oltA-5c7qA:
undetectable		 4oltA-5c7qA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB302_1
(CHITOSANASE)		 5c7q NUDF PROTEIN
(Bdellovibrio
bacteriovorus) 		4 / 5 THR A  11
THR A   8
ASP A  25
TYR A  39
 None
 1.08A 4oltB-5c7qA:
undetectable		 4oltB-5c7qA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA302_1
(CHITOSANASE)		 5c7q NUDF PROTEIN
(Bdellovibrio
bacteriovorus) 		4 / 5 THR A  11
THR A   8
ASP A  25
TYR A  39
 None
 1.10A 4qwpA-5c7qA:
undetectable		 4qwpA-5c7qA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB306_1
(CHITOSANASE)		 5c7q NUDF PROTEIN
(Bdellovibrio
bacteriovorus) 		4 / 5 THR A  11
THR A   8
ASP A  25
TYR A  39
 None
 1.16A 4qwpB-5c7qA:
undetectable		 4qwpB-5c7qA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 5c7q NUDF PROTEIN
(Bdellovibrio
bacteriovorus) 		4 / 6 ASP A 122
ALA A  45
THR A  85
THR A  88
 None
GOL  A 207 (-3.5A)
None
None
 1.46A 4w5qA-5c7qA:
undetectable		 4w5qA-5c7qA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5R_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 5c7q NUDF PROTEIN
(Bdellovibrio
bacteriovorus) 		4 / 6 ASP A 122
ALA A  45
THR A  85
THR A  88
 None
GOL  A 207 (-3.5A)
None
None
 1.45A 4w5rA-5c7qA:
undetectable		 4w5rA-5c7qA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 5c7q NUDF PROTEIN
(Bdellovibrio
bacteriovorus) 		4 / 6 ASP A 122
ALA A  45
THR A  85
THR A  88
 None
GOL  A 207 (-3.5A)
None
None
 1.49A 4w5tA-5c7qA:
undetectable		 4w5tA-5c7qA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5c7q NUDF PROTEIN
(Bdellovibrio
bacteriovorus) 		4 / 6 ASP A 122
ALA A  45
THR A  85
THR A  88
 None
GOL  A 207 (-3.5A)
None
None
 1.47A 4z4fA-5c7qA:
undetectable		 4z4fA-5c7qA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 5c7q NUDF PROTEIN
(Bdellovibrio
bacteriovorus) 		4 / 5 ASP A 122
ALA A  45
THR A  85
THR A  88
 None
GOL  A 207 (-3.5A)
None
None
 1.48A 4z4gA-5c7qA:
undetectable		 4z4gA-5c7qA:
11.36