SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5c8c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1871_0
(FPRA)		 5c8c VP0
(Enterovirus
A) 		4 / 7 PHE B 161
PRO B 152
ALA B 165
PHE B 314
 None
 1.07A 1lqtA-5c8cB:
undetectable		 1lqtA-5c8cB:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1428_0
(FPRA)		 5c8c VP0
(Enterovirus
A) 		4 / 7 PHE B 161
PRO B 152
ALA B 165
PHE B 314
 None
 1.06A 1lquA-5c8cB:
undetectable		 1lquA-5c8cB:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)		 5c8c VP1
(Enterovirus
A) 		4 / 4 VAL A 179
ALA A 188
LEU A 249
PHE A 137
 STE  A 301 (-4.6A)
None
None
None
 1.16A 1q97B-5c8cA:
undetectable		 1q97B-5c8cA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 5c8c VP0
VP1
(Enterovirus
A) 		5 / 12 GLY B 238
TYR B 148
LEU B 229
LEU B 244
TYR A 222
 None
 1.34A 1zgyA-5c8cB:
undetectable		 1zgyA-5c8cB:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_F_SPMF1433_1
(NITROALKANE OXIDASE)		 5c8c VP0
VP1
(Enterovirus
A) 		5 / 11 LEU B 244
ALA B 237
LEU B 201
LEU B 196
ASP A 206
 None
 1.30A 2c12F-5c8cB:
undetectable		 2c12F-5c8cB:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNC_A_CLUA808_1
(COPPER AMINE
OXIDASE, LIVER
ISOZYME)		 5c8c VP0
VP1
(Enterovirus
A) 		4 / 7 TYR B 148
TYR B 199
ASP A 206
TYR A 222
 None
 1.45A 2pncA-5c8cB:
undetectable		 2pncA-5c8cB:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5c8c VP1
VP0
(Enterovirus
A;
Enterovirus
A) 		4 / 7 GLN A 189
ILE B  30
SER A 191
TYR B  33
 None
 1.31A 2xz5D-5c8cA:
undetectable
2xz5E-5c8cA:
undetectable		 2xz5D-5c8cA:
21.09
2xz5E-5c8cA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GVU_A_STIA1001_2
(TYROSINE-PROTEIN
KINASE ABL2)		 5c8c VP0
(Enterovirus
A) 		4 / 5 VAL B 179
ILE B 307
TYR B 266
MET B 267
 None
 0.91A 3gvuA-5c8cB:
undetectable		 3gvuA-5c8cB:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB1_A_IMNA701_1
(LACTOTRANSFERRIN)		 5c8c VP0
(Enterovirus
A) 		4 / 4 PRO B 122
THR B 123
GLY B 162
THR B 156
 None
 1.02A 3ib1A-5c8cB:
undetectable		 3ib1A-5c8cB:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5c8c VP0
(Enterovirus
A) 		4 / 8 GLU B 211
ASN B 212
HIS B 214
ILE B 204
 None
None
None
CL  B 401 (-4.1A)
 1.22A 3kp6A-5c8cB:
undetectable
3kp6B-5c8cB:
undetectable		 3kp6A-5c8cB:
17.79
3kp6B-5c8cB:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_B_MRVB1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 5c8c VP1
(Enterovirus
A) 		4 / 5 TYR A 116
THR A 237
LEU A 151
THR A 136
 None
 1.18A 4mbsB-5c8cA:
undetectable		 4mbsB-5c8cA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_B_SALB801_1
(PROTEIN POLYBROMO-1)		 5c8c VP0
(Enterovirus
A) 		4 / 5 LEU B 284
TYR B 199
ALA B 237
ILE B 239
 None
 1.11A 4y03B-5c8cB:
undetectable		 4y03B-5c8cB:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5c8c VP0
(Enterovirus
A) 		3 / 3 SER B 274
ALA B 275
THR B 156
 None
 0.58A 5n0xB-5c8cB:
undetectable		 5n0xB-5c8cB:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5c8c VP1
(Enterovirus
A) 		4 / 8 THR A 232
TYR A 155
ARG A 236
GLN A 152
 None
STE  A 301 ( 4.5A)
None
None
 1.32A 5tzoC-5c8cA:
undetectable		 5tzoC-5c8cA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_B_PA1B204_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)		 5c8c VP0
VP1
(Enterovirus
A) 		3 / 3 GLY B 202
ASN A 278
ARG A 267
 None
 0.79A 5w7bD-5c8cB:
undetectable		 5w7bD-5c8cB:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBF_A_ACTA507_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 5c8c VP1
VP0
(Enterovirus
A;
Enterovirus
A) 		3 / 3 LYS A 256
SER B  20
SER B  18
 None
 0.93A 6gbfA-5c8cA:
undetectable		 6gbfA-5c8cA:
21.67