SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5c8p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 5c8p MOCVNH3 VARIANT
(Magnaporthe
oryzae) 		5 / 12 GLY A  70
ASP A  46
PHE A  77
ASN A  47
ILE A  69
 None
None
NAG  A 201 (-4.4A)
None
None
 1.31A 1lhuA-5c8pA:
undetectable		 1lhuA-5c8pA:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5c8p MOCVNH3 VARIANT
(Magnaporthe
oryzae) 		4 / 5 SER A  44
GLY A 101
HIS A  78
ASP A  90
 None
None
None
NAG  A 201 (-3.8A)
 1.12A 2oxtB-5c8pA:
undetectable		 2oxtB-5c8pA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 5c8p MOCVNH3 VARIANT
(Magnaporthe
oryzae) 		5 / 10 SER A  10
LEU A  21
SER A  35
ILE A 141
GLY A 142
 None
 1.34A 3ik6B-5c8pA:
undetectable
3ik6E-5c8pA:
undetectable		 3ik6B-5c8pA:
17.83
3ik6E-5c8pA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)		 5c8p MOCVNH3 VARIANT
(Magnaporthe
oryzae) 		5 / 10 SER A  54
LEU A 137
SER A  44
LEU A  43
LEU A  16
 None
 1.18A 4yiaA-5c8pA:
undetectable		 4yiaA-5c8pA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 5c8p MOCVNH3 VARIANT
(Magnaporthe
oryzae) 		3 / 3 ASN A  45
SER A 107
ARG A  82
 None
 0.88A 5b2qA-5c8pA:
undetectable		 5b2qA-5c8pA:
8.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 5c8p MOCVNH3 VARIANT
(Magnaporthe
oryzae) 		3 / 3 HIS A 140
GLU A 139
TRP A  52
 None
 1.14A 5odqD-5c8pA:
undetectable		 5odqD-5c8pA:
19.11