SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5c93'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5c93 HISTIDINE KINASE
(Lactobacillus
plantarum) 		5 / 12 ILE A 511
ILE A 605
LEU A 607
ILE A 499
ILE A 538
 None
 0.80A 1oipA-5c93A:
undetectable		 1oipA-5c93A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGP_A_PCFA1213_1
(WNT INHIBITORY
FACTOR 1)		 5c93 HISTIDINE KINASE
(Lactobacillus
plantarum) 		5 / 9 ILE A 511
ILE A 538
PHE A 504
ILE A 486
PHE A 490
 None
 1.47A 2ygpA-5c93A:
undetectable		 2ygpA-5c93A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5c93 HISTIDINE KINASE
(Lactobacillus
plantarum) 		4 / 8 GLY A 553
ASP A 551
ILE A 547
VAL A 593
 None
None
ACP  A 701 ( 4.8A)
None
 0.74A 3fi0B-5c93A:
undetectable		 3fi0B-5c93A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 5c93 HISTIDINE KINASE
(Lactobacillus
plantarum) 		4 / 6 ILE A 459
LEU A 607
LYS A 503
MET A 586
 None
None
SO4  A 704 ( 3.8A)
None
 1.02A 3sj1X-5c93A:
undetectable		 3sj1X-5c93A:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 5c93 HISTIDINE KINASE
(Lactobacillus
plantarum) 		4 / 7 ILE A 459
LEU A 607
LYS A 503
MET A 586
 None
None
SO4  A 704 ( 3.8A)
None
 0.97A 4hbfA-5c93A:
undetectable		 4hbfA-5c93A:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 5c93 HISTIDINE KINASE
(Lactobacillus
plantarum) 		4 / 7 ILE A 459
LEU A 607
LYS A 503
MET A 586
 None
None
SO4  A 704 ( 3.8A)
None
 1.05A 4hc3A-5c93A:
undetectable		 4hc3A-5c93A:
10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5c93 HISTIDINE KINASE
(Lactobacillus
plantarum) 		4 / 6 PHE A 490
MET A 512
ILE A 486
ASP A 471
 None
 1.04A 5iwuA-5c93A:
undetectable		 5iwuA-5c93A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_C_ZOLC401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 5c93 HISTIDINE KINASE
(Lactobacillus
plantarum) 		4 / 5 ASP A 430
ARG A 434
GLN A 426
LYS A 423
 None
 1.35A 6g31C-5c93A:
3.3		 6g31C-5c93A:
14.01