SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5c94'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VIF_A_FOLA1_0 (DIHYDROFOLATE REDUCTASE)	5c94	NON-STRUCTURAL PROTEIN 9 (Avian coronavirus)	3 / 3	GLN A 62 ILE A 63 TYR A 64	None	0.74A	1vifA-5c94A: undetectable	1vifA-5c94A: 19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HWK_A_BEZA301_0 (GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOT RANSFERASE)	5c94	NON-STRUCTURAL PROTEIN 9 (Avian coronavirus)	5 / 10	GLY A 98 GLY A 102 LEU A 101 LEU A 86 TYR A 30	None None PEG A 202 (-3.5A) None None	1.10A	5hwkA-5c94A: undetectable	5hwkA-5c94A: 18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HWK_B_BEZB301_0 (GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOT RANSFERASE)	5c94	NON-STRUCTURAL PROTEIN 9 (Avian coronavirus)	5 / 10	GLY A 98 GLY A 102 LEU A 101 LEU A 86 TYR A 30	None None PEG A 202 (-3.5A) None None	1.10A	5hwkB-5c94A: undetectable	5hwkB-5c94A: 18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F6I_A_8PRA509_1 (ENVELOPE GLYCOPROTEIN,GP,GP1 ENVELOPE GLYCOPROTEIN)	5c94	NON-STRUCTURAL PROTEIN 9 (Avian coronavirus)	5 / 12	VAL A 100 ALA A 103 GLY A 102 MET A 75 LEU A 86	None	0.98A	6f6iA-5c94A: undetectable 6f6iB-5c94A: undetectable	6f6iA-5c94A: 20.69 6f6iB-5c94A: 18.69

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1VIF_A_FOLA1_0","DIHYDROFOLATE REDUCTASE","5c94","NON-STRUCTURAL PROTEIN 9","Avian coronavirus",3,"GLN A  62;ILE A  63;TYR A  64","None","0.74A","1vifA-5c94A:undetectable","1vifA-5c94A:19.79"],["5HWK_A_BEZA301_0","GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE","5c94","NON-STRUCTURAL PROTEIN 9","Avian coronavirus",5,"GLY A  98;GLY A 102;LEU A 101;LEU A  86;TYR A  30","None;None;PEG A 202 (-3.5A);None;None","1.10A","5hwkA-5c94A:undetectable","5hwkA-5c94A:18.67"],["5HWK_B_BEZB301_0","GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE","5c94","NON-STRUCTURAL PROTEIN 9","Avian coronavirus",5,"GLY A  98;GLY A 102;LEU A 101;LEU A  86;TYR A  30","None;None;PEG A 202 (-3.5A);None;None","1.10A","5hwkB-5c94A:undetectable","5hwkB-5c94A:18.67"],["6F6I_A_8PRA509_1","ENVELOPE GLYCOPROTEIN,GP,GP1;ENVELOPE GLYCOPROTEIN","5c94","NON-STRUCTURAL PROTEIN 9","Avian coronavirus",5,"VAL A 100;ALA A 103;GLY A 102;MET A  75;LEU A  86","None","0.98A","6f6iA-5c94A:undetectable;6f6iB-5c94A:undetectable","6f6iA-5c94A:20.69;6f6iB-5c94A:18.69"]]