SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5c9h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 8 GLN A 382
PHE A 379
LEU A 405
PHE A 401
None
0.80A 1v54C-5c9hA:
undetectable
1v54J-5c9hA:
undetectable
1v54C-5c9hA:
18.61
1v54J-5c9hA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 8 GLN A 382
PHE A 379
LEU A 405
PHE A 401
None
0.86A 1v54P-5c9hA:
undetectable
1v54W-5c9hA:
undetectable
1v54P-5c9hA:
18.61
1v54W-5c9hA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 7 GLN A 382
PHE A 379
LEU A 405
PHE A 401
None
0.93A 1v55C-5c9hA:
undetectable
1v55J-5c9hA:
undetectable
1v55C-5c9hA:
18.61
1v55J-5c9hA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 7 PHE A 310
GLU A 303
VAL A 435
VAL A 431
None
1.26A 1zzrA-5c9hA:
undetectable
1zzrB-5c9hA:
undetectable
1zzrA-5c9hA:
18.62
1zzrB-5c9hA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 8 GLN A 382
PHE A 379
LEU A 405
PHE A 401
None
0.79A 2dyrC-5c9hA:
undetectable
2dyrJ-5c9hA:
undetectable
2dyrC-5c9hA:
18.61
2dyrJ-5c9hA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 8 GLN A 382
PHE A 379
LEU A 405
PHE A 401
None
0.81A 2dyrP-5c9hA:
undetectable
2dyrW-5c9hA:
undetectable
2dyrP-5c9hA:
18.61
2dyrW-5c9hA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 7 GLN A 382
PHE A 379
LEU A 405
PHE A 401
None
0.83A 2eijC-5c9hA:
undetectable
2eijJ-5c9hA:
undetectable
2eijC-5c9hA:
18.61
2eijJ-5c9hA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 8 GLN A 382
PHE A 379
LEU A 405
PHE A 401
None
0.89A 2eilC-5c9hA:
undetectable
2eilJ-5c9hA:
undetectable
2eilC-5c9hA:
18.61
2eilJ-5c9hA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 7 GLN A 382
PHE A 379
LEU A 405
PHE A 401
None
0.89A 2eimC-5c9hA:
undetectable
2eimJ-5c9hA:
undetectable
2eimC-5c9hA:
18.61
2eimJ-5c9hA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 7 GLN A 382
PHE A 379
LEU A 405
PHE A 401
None
0.88A 2einC-5c9hA:
undetectable
2einJ-5c9hA:
undetectable
2einC-5c9hA:
18.61
2einJ-5c9hA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 6 GLN A 382
PHE A 379
LEU A 405
PHE A 401
None
0.86A 2einP-5c9hA:
undetectable
2einW-5c9hA:
undetectable
2einP-5c9hA:
18.61
2einW-5c9hA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA802_1
(TRANSPORTER)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 6 ILE A 488
ARG A 473
ILE A 469
PHE A 408
None
A  D  10 ( 4.2A)
None
None
0.94A 2q72A-5c9hA:
1.0
2q72A-5c9hA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 6 GLN A 382
PHE A 379
LEU A 405
PHE A 401
None
0.78A 2zxwP-5c9hA:
undetectable
2zxwW-5c9hA:
undetectable
2zxwP-5c9hA:
18.61
2zxwW-5c9hA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 5 GLN A 382
PHE A 379
LEU A 405
PHE A 401
None
0.77A 3ablC-5c9hA:
undetectable
3ablJ-5c9hA:
undetectable
3ablC-5c9hA:
18.61
3ablJ-5c9hA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 6 GLN A 382
PHE A 379
LEU A 405
PHE A 401
None
0.92A 3ablP-5c9hA:
undetectable
3ablW-5c9hA:
undetectable
3ablP-5c9hA:
18.61
3ablW-5c9hA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 6 GLN A 382
PHE A 379
LEU A 405
PHE A 401
None
0.68A 3ag1C-5c9hA:
undetectable
3ag1J-5c9hA:
undetectable
3ag1C-5c9hA:
18.61
3ag1J-5c9hA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 8 GLN A 382
PHE A 379
LEU A 405
PHE A 401
None
0.85A 3ag4C-5c9hA:
undetectable
3ag4J-5c9hA:
undetectable
3ag4C-5c9hA:
18.61
3ag4J-5c9hA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 7 GLN A 382
PHE A 379
LEU A 405
PHE A 401
None
0.92A 3ag4P-5c9hA:
undetectable
3ag4W-5c9hA:
undetectable
3ag4P-5c9hA:
18.61
3ag4W-5c9hA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 7 GLN A 382
PHE A 379
LEU A 405
PHE A 401
None
0.85A 3asnC-5c9hA:
undetectable
3asnJ-5c9hA:
undetectable
3asnC-5c9hA:
18.61
3asnJ-5c9hA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 7 VAL A 435
VAL A 431
PHE A 310
GLU A 303
None
1.28A 3dqrA-5c9hA:
undetectable
3dqrB-5c9hA:
undetectable
3dqrA-5c9hA:
18.76
3dqrB-5c9hA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 7 PHE A 310
GLU A 303
VAL A 435
VAL A 431
None
1.26A 3jx4A-5c9hA:
0.7
3jx4B-5c9hA:
0.8
3jx4A-5c9hA:
18.76
3jx4B-5c9hA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 7 PHE A 310
GLU A 303
VAL A 435
VAL A 431
None
1.29A 3jx5A-5c9hA:
undetectable
3jx5B-5c9hA:
1.1
3jx5A-5c9hA:
18.76
3jx5B-5c9hA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 6 VAL A 435
VAL A 431
PHE A 310
GLU A 303
None
1.31A 3n61A-5c9hA:
0.8
3n61B-5c9hA:
0.8
3n61A-5c9hA:
18.76
3n61B-5c9hA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 7 PHE A 310
GLU A 303
VAL A 435
VAL A 431
None
1.28A 3n61A-5c9hA:
undetectable
3n61B-5c9hA:
undetectable
3n61A-5c9hA:
18.76
3n61B-5c9hA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 7 VAL A 435
VAL A 431
PHE A 310
GLU A 303
None
1.27A 3nlpA-5c9hA:
undetectable
3nlpB-5c9hA:
undetectable
3nlpA-5c9hA:
18.76
3nlpB-5c9hA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 7 VAL A 435
VAL A 431
PHE A 310
GLU A 303
None
1.26A 3nlrA-5c9hA:
undetectable
3nlrB-5c9hA:
undetectable
3nlrA-5c9hA:
18.76
3nlrB-5c9hA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_C_ACTC401_0
(PROTON-GATED ION
CHANNEL)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 7 ILE A 314
PHE A 247
VAL A 388
ILE A 384
None
0.97A 4zzbC-5c9hA:
undetectable
4zzbD-5c9hA:
undetectable
4zzbC-5c9hA:
19.54
4zzbD-5c9hA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 7 PHE A 310
GLU A 303
VAL A 435
VAL A 431
None
1.28A 5adeA-5c9hA:
undetectable
5adeB-5c9hA:
undetectable
5adeA-5c9hA:
18.76
5adeB-5c9hA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 6 GLN A 382
PHE A 379
LEU A 405
PHE A 401
None
1.02A 5b1bC-5c9hA:
undetectable
5b1bJ-5c9hA:
undetectable
5b1bC-5c9hA:
18.61
5b1bJ-5c9hA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 7 GLN A 382
PHE A 379
LEU A 405
PHE A 401
None
0.88A 5b1bP-5c9hA:
undetectable
5b1bW-5c9hA:
undetectable
5b1bP-5c9hA:
18.61
5b1bW-5c9hA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 7 PHE A 310
GLU A 303
VAL A 435
VAL A 431
None
1.27A 5g0pA-5c9hA:
undetectable
5g0pB-5c9hA:
undetectable
5g0pA-5c9hA:
18.76
5g0pB-5c9hA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 6 GLN A 382
PHE A 379
LEU A 405
PHE A 401
None
0.96A 5z84P-5c9hA:
undetectable
5z84W-5c9hA:
undetectable
5z84P-5c9hA:
18.61
5z84W-5c9hA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 6 GLN A 382
PHE A 379
LEU A 405
PHE A 401
None
1.04A 5z85P-5c9hA:
undetectable
5z85W-5c9hA:
undetectable
5z85P-5c9hA:
18.61
5z85W-5c9hA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 6 GLN A 382
PHE A 379
LEU A 405
PHE A 401
None
0.93A 5z86C-5c9hA:
undetectable
5z86J-5c9hA:
undetectable
5z86C-5c9hA:
18.61
5z86J-5c9hA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 6 GLN A 382
PHE A 379
LEU A 405
PHE A 401
None
0.96A 5z86P-5c9hA:
undetectable
5z86W-5c9hA:
undetectable
5z86P-5c9hA:
18.61
5z86W-5c9hA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 7 GLN A 382
PHE A 379
LEU A 405
PHE A 401
None
0.89A 5zcoC-5c9hA:
undetectable
5zcoJ-5c9hA:
undetectable
5zcoC-5c9hA:
18.61
5zcoJ-5c9hA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 6 GLN A 382
PHE A 379
LEU A 405
PHE A 401
None
0.96A 5zcoP-5c9hA:
undetectable
5zcoW-5c9hA:
undetectable
5zcoP-5c9hA:
18.61
5zcoW-5c9hA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 6 GLN A 382
PHE A 379
LEU A 405
PHE A 401
None
0.93A 5zcpC-5c9hA:
undetectable
5zcpJ-5c9hA:
undetectable
5zcpC-5c9hA:
18.61
5zcpJ-5c9hA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 6 GLN A 382
PHE A 379
LEU A 405
PHE A 401
None
0.98A 5zcpP-5c9hA:
undetectable
5zcpW-5c9hA:
undetectable
5zcpP-5c9hA:
18.61
5zcpW-5c9hA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 7 GLN A 382
PHE A 379
LEU A 405
PHE A 401
None
0.90A 5zcqC-5c9hA:
undetectable
5zcqJ-5c9hA:
undetectable
5zcqC-5c9hA:
18.61
5zcqJ-5c9hA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5c9h TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila)
4 / 6 GLN A 382
PHE A 379
LEU A 405
PHE A 401
None
1.03A 6nmpC-5c9hA:
undetectable
6nmpJ-5c9hA:
undetectable
6nmpC-5c9hA:
18.61
6nmpJ-5c9hA:
11.36