SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5c9i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC6_0
(GRAMICIDIN A)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		3 / 3 ALA A 275
VAL A 392
TRP A 391
 None
 0.93A 1gmkC-5c9iA:
undetectable
1gmkD-5c9iA:
undetectable		 1gmkC-5c9iA:
2.18
1gmkD-5c9iA:
2.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		5 / 12 THR A 274
SER A 273
PHE A 499
SER A 482
LEU A 492
 None
 1.25A 1q23B-5c9iA:
undetectable		 1q23B-5c9iA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		5 / 12 THR A 274
SER A 273
PHE A 499
SER A 482
LEU A 492
 None
 1.32A 1q23C-5c9iA:
undetectable		 1q23C-5c9iA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_F_FUAF704_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		5 / 11 THR A 274
SER A 273
PHE A 499
SER A 482
LEU A 492
 None
 1.27A 1q23F-5c9iA:
undetectable		 1q23F-5c9iA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		5 / 11 THR A 274
SER A 273
PHE A 499
SER A 482
LEU A 492
 None
 1.26A 1q23I-5c9iA:
undetectable		 1q23I-5c9iA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_1
(ESTROGEN RECEPTOR
BETA)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		5 / 12 ALA A  98
GLU A  97
ILE A 172
ILE A 353
LEU A 161
 None
 0.92A 1qknA-5c9iA:
undetectable		 1qknA-5c9iA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		3 / 3 SER A  63
GLY A  68
ARG A 323
 None
 0.67A 1t9wA-5c9iA:
undetectable		 1t9wA-5c9iA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_D_DVAD8_0
(GRAMICIDIN D)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		3 / 3 VAL A 542
VAL A 537
TRP A 752
 None
 0.97A 1w5uC-5c9iA:
undetectable
1w5uD-5c9iA:
undetectable		 1w5uC-5c9iA:
2.18
1w5uD-5c9iA:
2.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2003_1
(SERUM ALBUMIN)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		5 / 10 ARG A  62
ILE A 147
ARG A  59
PHE A 117
GLY A 254
 None
 1.12A 2bxqA-5c9iA:
undetectable		 2bxqA-5c9iA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_A_GBNA2414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		4 / 8 GLY A 209
THR A 210
ALA A 211
ALA A 212
 None
 0.58A 2ej3A-5c9iA:
undetectable		 2ej3A-5c9iA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H79_A_T3A1_1
(THRA PROTEIN)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		5 / 12 ILE A 389
ILE A 409
ALA A 387
ARG A 362
ILE A 498
 None
 1.04A 2h79A-5c9iA:
undetectable		 2h79A-5c9iA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HTQ_A_ZMRA472_1
(NEURAMINIDASE)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		5 / 12 GLU A 602
ARG A 606
ARG A 659
TYR A 683
TYR A 698
 None
 1.40A 2htqA-5c9iA:
undetectable		 2htqA-5c9iA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA8_0
(GRAMICIDIN D)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		3 / 3 VAL A 537
TRP A 752
VAL A 542
 None
 0.92A 2izqA-5c9iA:
undetectable
2izqB-5c9iA:
undetectable		 2izqA-5c9iA:
2.18
2izqB-5c9iA:
2.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_B_ACTB141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		3 / 3 PRO A 390
ASN A 360
ARG A 362
 None
 1.02A 2qeuB-5c9iA:
undetectable		 2qeuB-5c9iA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		4 / 7 GLY A 514
MET A 517
GLY A 202
PHE A 221
 None
 0.92A 2qwxA-5c9iA:
undetectable
2qwxB-5c9iA:
undetectable		 2qwxA-5c9iA:
14.30
2qwxB-5c9iA:
14.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_A_RBFA200_1
(DODECIN)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		4 / 8 TYR A 326
TRP A 345
GLN A 176
GLN A 347
 None
 1.10A 2vxaA-5c9iA:
undetectable
2vxaC-5c9iA:
undetectable
2vxaE-5c9iA:
undetectable		 2vxaA-5c9iA:
6.48
2vxaC-5c9iA:
6.48
2vxaE-5c9iA:
6.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_B_RBFB200_1
(DODECIN)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		4 / 8 GLN A 176
TYR A 326
TRP A 345
GLN A 347
 None
 1.14A 2vxaA-5c9iA:
undetectable
2vxaB-5c9iA:
undetectable
2vxaK-5c9iA:
undetectable		 2vxaA-5c9iA:
6.48
2vxaB-5c9iA:
6.48
2vxaK-5c9iA:
6.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_C_RBFC200_1
(DODECIN)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		4 / 8 GLN A 176
TYR A 326
TRP A 345
GLN A 347
 None
 1.12A 2vxaB-5c9iA:
undetectable
2vxaC-5c9iA:
undetectable
2vxaG-5c9iA:
undetectable		 2vxaB-5c9iA:
6.48
2vxaC-5c9iA:
6.48
2vxaG-5c9iA:
6.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_D_RBFD200_1
(DODECIN)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		4 / 8 TYR A 326
TRP A 345
GLN A 176
GLN A 347
 None
 1.10A 2vxaD-5c9iA:
undetectable
2vxaF-5c9iA:
undetectable
2vxaI-5c9iA:
undetectable		 2vxaD-5c9iA:
6.48
2vxaF-5c9iA:
6.48
2vxaI-5c9iA:
6.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_E_RBFE200_1
(DODECIN)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		4 / 8 GLN A 176
TYR A 326
TRP A 345
GLN A 347
 None
 1.14A 2vxaD-5c9iA:
undetectable
2vxaE-5c9iA:
undetectable
2vxaL-5c9iA:
undetectable		 2vxaD-5c9iA:
6.48
2vxaE-5c9iA:
6.48
2vxaL-5c9iA:
6.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_G_RBFG200_1
(DODECIN)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		4 / 8 GLN A 347
TYR A 326
TRP A 345
GLN A 176
 None
 1.13A 2vxaF-5c9iA:
undetectable
2vxaG-5c9iA:
undetectable
2vxaI-5c9iA:
undetectable		 2vxaF-5c9iA:
6.48
2vxaG-5c9iA:
6.48
2vxaI-5c9iA:
6.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_H_RBFH200_1
(DODECIN)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		4 / 8 GLN A 347
GLN A 176
TYR A 326
TRP A 345
 None
 1.08A 2vxaB-5c9iA:
undetectable
2vxaG-5c9iA:
undetectable
2vxaH-5c9iA:
undetectable		 2vxaB-5c9iA:
6.48
2vxaG-5c9iA:
6.48
2vxaH-5c9iA:
6.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_I_RBFI200_1
(DODECIN)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		4 / 8 GLN A 176
TYR A 326
TRP A 345
GLN A 347
 None
 1.14A 2vxaH-5c9iA:
undetectable
2vxaI-5c9iA:
undetectable
2vxaJ-5c9iA:
undetectable		 2vxaH-5c9iA:
6.48
2vxaI-5c9iA:
6.48
2vxaJ-5c9iA:
6.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_J_RBFJ200_1
(DODECIN)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		4 / 8 GLN A 347
TYR A 326
TRP A 345
GLN A 176
 None
 1.14A 2vxaD-5c9iA:
undetectable
2vxaJ-5c9iA:
undetectable
2vxaL-5c9iA:
undetectable		 2vxaD-5c9iA:
6.48
2vxaJ-5c9iA:
6.48
2vxaL-5c9iA:
6.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_K_RBFK200_1
(DODECIN)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		4 / 8 GLN A 347
GLN A 176
TYR A 326
TRP A 345
 None
 1.14A 2vxaH-5c9iA:
undetectable
2vxaJ-5c9iA:
undetectable
2vxaK-5c9iA:
undetectable		 2vxaH-5c9iA:
6.48
2vxaJ-5c9iA:
6.48
2vxaK-5c9iA:
6.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_L_RBFL200_1
(DODECIN)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		4 / 8 GLN A 347
GLN A 176
TYR A 326
TRP A 345
 None
 1.14A 2vxaA-5c9iA:
undetectable
2vxaK-5c9iA:
undetectable
2vxaL-5c9iA:
undetectable		 2vxaA-5c9iA:
6.48
2vxaK-5c9iA:
6.48
2vxaL-5c9iA:
6.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1160_1
(ALLERGEN ARG R 1)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		4 / 6 SER A 594
VAL A 547
TYR A 683
ASP A 587
 None
 1.31A 2x45A-5c9iA:
undetectable		 2x45A-5c9iA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		5 / 12 LEU A 663
PHE A 221
ASN A 204
ASN A 708
TYR A 747
 None
 1.17A 2y00A-5c9iA:
undetectable		 2y00A-5c9iA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		5 / 12 GLY A 254
SER A 251
ILE A 258
LEU A 239
MET A 113
 None
 1.16A 3adsB-5c9iA:
undetectable		 3adsB-5c9iA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_3
(PHOSPHOLIPASE A2)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		5 / 12 LEU A 543
ILE A 686
SER A 707
SER A 709
THR A 728
 None
 1.24A 3bjwF-5c9iA:
undetectable		 3bjwF-5c9iA:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWS_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		5 / 12 ILE A 389
ILE A 409
ALA A 387
ARG A 362
ILE A 498
 None
 1.08A 3gwsX-5c9iA:
undetectable		 3gwsX-5c9iA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		3 / 3 GLU A 761
GLY A 764
THR A 763
 None
 0.53A 3iazA-5c9iA:
undetectable		 3iazA-5c9iA:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q87_B_SAMB300_0
(N6 ADENINE SPECIFIC
DNA METHYLASE)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		5 / 12 GLY A  60
SER A  86
ILE A  94
ASP A  87
ASN A  83
 None
 1.15A 3q87B-5c9iA:
undetectable		 3q87B-5c9iA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXV_D_MTXD2000_2
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		3 / 3 LEU A  72
ARG A  91
ASN A 174
 None
 0.77A 3qxvD-5c9iA:
undetectable		 3qxvD-5c9iA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXV_D_MTXD2000_2
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		3 / 3 LEU A  78
ARG A  91
ASN A 174
 None
 0.66A 3qxvD-5c9iA:
undetectable		 3qxvD-5c9iA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_0
(2'-O-METHYL
TRANSFERASE)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		5 / 12 ASN A 478
GLY A 514
GLY A 477
MET A 513
PHE A 548
 None
 1.47A 3r24A-5c9iA:
undetectable		 3r24A-5c9iA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_B_IL2B901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		5 / 12 LEU A 612
VAL A 607
LEU A 558
VAL A 557
TYR A 698
 None
 1.25A 3sp9B-5c9iA:
undetectable		 3sp9B-5c9iA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		5 / 10 THR A 274
SER A 273
PHE A 499
SER A 482
LEU A 492
 None
 1.37A 3u9fI-5c9iA:
undetectable		 3u9fI-5c9iA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_B_017B202_1
(PROTEASE)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		4 / 7 TRP A 450
ARG A 354
GLY A 331
PRO A 332
 None
 1.35A 3ucbB-5c9iA:
undetectable		 3ucbB-5c9iA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VM4_A_IZPA1_1
(FATTY ACID
ALPHA-HYDROXYLASE)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		4 / 5 LEU A 509
ARG A 512
PRO A 626
ALA A 506
 None
 1.29A 3vm4A-5c9iA:
undetectable		 3vm4A-5c9iA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		4 / 5 VAL A  24
GLY A  23
TYR A 235
ASP A  46
 None
 1.40A 3w9tA-5c9iA:
undetectable		 3w9tA-5c9iA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		4 / 5 VAL A  24
GLY A  23
TYR A 235
ASP A  46
 None
 1.40A 3w9tB-5c9iA:
undetectable		 3w9tB-5c9iA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		4 / 5 VAL A  24
GLY A  23
TYR A 235
ASP A  46
 None
 1.39A 3w9tC-5c9iA:
undetectable		 3w9tC-5c9iA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		4 / 5 VAL A  24
GLY A  23
TYR A 235
ASP A  46
 None
 1.40A 3w9tD-5c9iA:
undetectable		 3w9tD-5c9iA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		4 / 5 VAL A  24
GLY A  23
TYR A 235
ASP A  46
 None
 1.40A 3w9tE-5c9iA:
undetectable		 3w9tE-5c9iA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		4 / 5 VAL A  24
GLY A  23
TYR A 235
ASP A  46
 None
 1.40A 3w9tF-5c9iA:
undetectable		 3w9tF-5c9iA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		4 / 5 VAL A  24
GLY A  23
TYR A 235
ASP A  46
 None
 1.40A 3w9tG-5c9iA:
undetectable		 3w9tG-5c9iA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD392_1
(TETX2 PROTEIN)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		4 / 5 HIS A 724
SER A 535
GLN A 722
VAL A 219
 None
 1.13A 4a99D-5c9iA:
undetectable		 4a99D-5c9iA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF2_A_4CHA506_0
(NADPH DEHYDROGENASE)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		4 / 6 THR A 725
TYR A 710
HIS A  26
TYR A 743
 None
 1.42A 4df2A-5c9iA:
undetectable		 4df2A-5c9iA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		5 / 12 ALA A 267
ALA A 723
VAL A 714
VAL A 247
GLN A 238
 None
 1.26A 4df3B-5c9iA:
undetectable		 4df3B-5c9iA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		5 / 12 ASN A 160
ASP A 408
GLY A 410
GLN A 458
ILE A 389
 None
 1.41A 4djeA-5c9iA:
undetectable		 4djeA-5c9iA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		5 / 12 ASN A 160
ASP A 408
GLY A 410
GLN A 458
ILE A 389
 None
 1.41A 4djfA-5c9iA:
undetectable		 4djfA-5c9iA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_2
(FOLATE RECEPTOR BETA)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		3 / 3 TYR A 157
GLN A 458
TRP A 391
 None
 1.04A 4kn2C-5c9iA:
undetectable		 4kn2C-5c9iA:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_2
(FOLATE RECEPTOR BETA)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		3 / 3 TYR A 165
GLN A 458
TRP A 391
 None
 1.07A 4kn2C-5c9iA:
undetectable		 4kn2C-5c9iA:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMA_A_CXXA603_1
(TRANSPORTER)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		5 / 11 ALA A 267
SER A 375
SER A 265
GLY A 398
THR A 394
 None
 1.01A 4mmaA-5c9iA:
undetectable		 4mmaA-5c9iA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NED_A_PFNA709_1
(LACTOTRANSFERRIN)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		4 / 6 ASP A 355
VAL A 412
SER A 273
ALA A 162
 None
 1.06A 4nedA-5c9iA:
undetectable		 4nedA-5c9iA:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QKN_A_JMSA602_1
(ALPHA-KETOGLUTARATE-
DEPENDENT
DIOXYGENASE FTO)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		4 / 8 LEU A  48
THR A  50
ARG A 233
HIS A 740
 None
 1.08A 4qknA-5c9iA:
undetectable		 4qknA-5c9iA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U3E_A_ACTA705_0
(RIBONUCLEOSIDE
TRIPHOSPHATE
REDUCTASE)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		4 / 4 HIS A 489
ASP A 474
TYR A 475
VAL A 488
 None
 1.44A 4u3eA-5c9iA:
0.0		 4u3eA-5c9iA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_RTZA3009_1
(ALDEHYDE OXIDASE)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		4 / 8 HIS A  65
GLU A  61
ARG A 312
PRO A 310
 None
 1.10A 4uhxA-5c9iA:
undetectable		 4uhxA-5c9iA:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YFB_C_PACC601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		12 / 12 SER A 203
PRO A 224
TRP A 226
PHE A 234
PHE A 252
GLN A 259
ILE A 260
HIS A 270
VAL A 272
TRP A 367
TRP A 391
VAL A 392
 None
 0.20A 4yfbC-5c9iA:
44.7		 4yfbC-5c9iA:
74.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YFB_F_PACF601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		12 / 12 SER A 203
PRO A 224
TRP A 226
PHE A 234
PHE A 252
GLN A 259
ILE A 260
HIS A 270
VAL A 272
TRP A 367
TRP A 391
VAL A 392
 None
 0.20A 4yfbF-5c9iA:
44.6		 4yfbF-5c9iA:
74.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YFB_I_PACI601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		12 / 12 SER A 203
PRO A 224
TRP A 226
PHE A 234
PHE A 252
GLN A 259
ILE A 260
HIS A 270
VAL A 272
TRP A 367
TRP A 391
VAL A 392
 None
 0.23A 4yfbI-5c9iA:
44.4		 4yfbI-5c9iA:
74.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YFB_L_PACL601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		12 / 12 SER A 203
PRO A 224
TRP A 226
PHE A 234
PHE A 252
GLN A 259
ILE A 260
HIS A 270
VAL A 272
TRP A 367
TRP A 391
VAL A 392
 None
 0.21A 4yfbL-5c9iA:
44.5		 4yfbL-5c9iA:
74.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZ8_A_GCSA208_1
(GLUCANASE/CHITOSANAS
E)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		4 / 7 GLU A 775
ARG A 126
TYR A  37
TYR A  41
 None
 1.20A 4zz8A-5c9iA:
undetectable		 4zz8A-5c9iA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DB5_A_CYSA503_0
(CYSTEINE DESULFURASE)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		4 / 8 ALA A 159
HIS A  90
ARG A 155
THR A  77
 None
 1.03A 5db5A-5c9iA:
undetectable
5db5B-5c9iA:
undetectable		 5db5A-5c9iA:
20.79
5db5B-5c9iA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		5 / 12 THR A 725
GLN A 712
VAL A 266
SER A 535
VAL A 538
 None
 1.30A 6bzoC-5c9iA:
undetectable		 6bzoC-5c9iA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECE_C_DVAC3010_0
(VLM2
DODECADEPSIPEPTIDE)		 5c9i PROTEIN RELATED TO
PENICILLIN ACYLASE
(Acidovorax
sp.
MR-S7) 		3 / 3 ALA A 430
PHE A 440
GLN A 282
 None
 0.84A 6eceA-5c9iA:
undetectable		 6eceA-5c9iA:
18.57