SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5c9j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1BDW_B_DVAB8_0 (GRAMICIDIN A)	5c9j	T-CELL SURFACE GLYCOPROTEIN CD1C,T-CELL SURFACE GLYCOPROTEIN CD1B (Homo sapiens)	3 / 3	VAL A 15 VAL A 101 TRP A 34	STE A 303 ( 4.7A) None PO4 A 308 (-3.2A)	0.70A	1bdwA-5c9jA: undetectable 1bdwB-5c9jA: undetectable	1bdwA-5c9jA: 4.62 1bdwB-5c9jA: 4.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E7A_B_PFLB4001_1 (SERUM ALBUMIN)	5c9j	T-CELL SURFACE GLYCOPROTEIN CD1C,T-CELL SURFACE GLYCOPROTEIN CD1B (Homo sapiens)	5 / 9	LEU A 66 ILE A 50 PHE A 13 LEU A 177 GLY A 33	None STE A 303 ( 3.9A) STE A 303 ( 4.8A) None STE A 303 ( 4.2A)	1.20A	1e7aB-5c9jA: undetectable	1e7aB-5c9jA: 17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICT_D_T44D129_2 (TRANSTHYRETIN)	5c9j	T-CELL SURFACE GLYCOPROTEIN CD1C,T-CELL SURFACE GLYCOPROTEIN CD1B (Homo sapiens)	4 / 7	LEU A 240 THR A 252 SER A 213 VAL A 209	None	0.82A	1ictD-5c9jA: undetectable	1ictD-5c9jA: 16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FU8_A_ACTA302_0 (UROKINASE-TYPE PLASMINOGEN ACTIVATOR)	5c9j	T-CELL SURFACE GLYCOPROTEIN CD1C,T-CELL SURFACE GLYCOPROTEIN CD1B (Homo sapiens)	4 / 5	HIS A 211 GLN A 207 GLY A 198 SER A 196	None	1.23A	4fu8A-5c9jA: undetectable	4fu8A-5c9jA: 22.88

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1BDW_B_DVAB8_0","GRAMICIDIN A","5c9j","T-CELL SURFACE GLYCOPROTEIN CD1C,T-CELL SURFACE GLYCOPROTEIN CD1B","Homo sapiens",3,"VAL A  15;VAL A 101;TRP A  34","STE A 303 ( 4.7A);None;PO4 A 308 (-3.2A)","0.70A","1bdwA-5c9jA:undetectable;1bdwB-5c9jA:undetectable","1bdwA-5c9jA:4.62;1bdwB-5c9jA:4.62"],["1E7A_B_PFLB4001_1","SERUM ALBUMIN","5c9j","T-CELL SURFACE GLYCOPROTEIN CD1C,T-CELL SURFACE GLYCOPROTEIN CD1B","Homo sapiens",5,"LEU A  66;ILE A  50;PHE A  13;LEU A 177;GLY A  33","None;STE A 303 ( 3.9A);STE A 303 ( 4.8A);None;STE A 303 ( 4.2A)","1.20A","1e7aB-5c9jA:undetectable","1e7aB-5c9jA:17.88"],["1ICT_D_T44D129_2","TRANSTHYRETIN","5c9j","T-CELL SURFACE GLYCOPROTEIN CD1C,T-CELL SURFACE GLYCOPROTEIN CD1B","Homo sapiens",4,"LEU A 240;THR A 252;SER A 213;VAL A 209","None","0.82A","1ictD-5c9jA:undetectable","1ictD-5c9jA:16.91"],["4FU8_A_ACTA302_0","UROKINASE-TYPE PLASMINOGEN ACTIVATOR","5c9j","T-CELL SURFACE GLYCOPROTEIN CD1C,T-CELL SURFACE GLYCOPROTEIN CD1B","Homo sapiens",4,"HIS A 211;GLN A 207;GLY A 198;SER A 196","None","1.23A","4fu8A-5c9jA:undetectable","4fu8A-5c9jA:22.88"]]