SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5c9l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB8_0
(GRAMICIDIN A)		 5c9l PLL LECTIN
(Photorhabdus
luminescens) 		3 / 3 VAL A  91
VAL A  89
TRP A  99
 None
None
EDO  A 413 (-3.6A)
 0.95A 1bdwA-5c9lA:
undetectable
1bdwB-5c9lA:
undetectable		 1bdwA-5c9lA:
4.52
1bdwB-5c9lA:
4.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 5c9l PLL LECTIN
(Photorhabdus
luminescens) 		3 / 3 GLU A  88
TRP A 102
LYS A 273
 None
 1.31A 1qu2A-5c9lA:
undetectable		 1qu2A-5c9lA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 5c9l PLL LECTIN
(Photorhabdus
luminescens) 		3 / 3 GLU A 136
TRP A 150
LYS A 320
 None
None
PG4  A 407 ( 4.7A)
 1.41A 1qu2A-5c9lA:
undetectable		 1qu2A-5c9lA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W0G_A_MYTA1499_1
(CYTOCHROME P450 3A4)		 5c9l PLL LECTIN
(Photorhabdus
luminescens) 		4 / 6 SER A 240
ILE A  17
ALA A  23
ALA A 283
 None
 0.94A 1w0gA-5c9lA:
undetectable		 1w0gA-5c9lA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOX_A_THAA400_1
(HISTAMINE
N-METHYLTRANSFERASE)		 5c9l PLL LECTIN
(Photorhabdus
luminescens) 		4 / 8 PHE A  69
PHE A  41
GLU A  39
GLN A 103
 None
 1.15A 2aoxA-5c9lA:
undetectable		 2aoxA-5c9lA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOX_B_THAB401_1
(HISTAMINE
N-METHYLTRANSFERASE)		 5c9l PLL LECTIN
(Photorhabdus
luminescens) 		4 / 7 PHE A  69
PHE A  41
GLU A  39
GLN A 103
 None
 1.15A 2aoxB-5c9lA:
undetectable		 2aoxB-5c9lA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 5c9l PLL LECTIN
(Photorhabdus
luminescens) 		4 / 7 SER A 215
ARG A 243
LEU A 242
HIS A 244
 None
 1.07A 2f78B-5c9lA:
undetectable		 2f78B-5c9lA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 5c9l PLL LECTIN
(Photorhabdus
luminescens) 		4 / 6 SER A 215
ARG A 243
LEU A 242
HIS A 244
 None
 1.31A 2f8dA-5c9lA:
undetectable		 2f8dA-5c9lA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA8_0
(GRAMICIDIN D)		 5c9l PLL LECTIN
(Photorhabdus
luminescens) 		3 / 3 VAL A  72
TRP A 114
VAL A  49
 None
 0.95A 2izqA-5c9lA:
undetectable
2izqB-5c9lA:
undetectable		 2izqA-5c9lA:
4.52
2izqB-5c9lA:
4.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RK8_A_PPFA3969_1
(PHOSPHOENOLPYRUVATE
CARBOXYKINASE,
CYTOSOLIC [GTP])		 5c9l PLL LECTIN
(Photorhabdus
luminescens) 		4 / 8 ARG A 236
ASP A 220
ARG A 188
ALA A  21
 None
 1.42A 2rk8A-5c9lA:
undetectable		 2rk8A-5c9lA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_2
(AAC(6')-IB)		 5c9l PLL LECTIN
(Photorhabdus
luminescens) 		3 / 3 TRP A 294
GLN A 342
TRP A 291
 None
None
EDO  A 409 (-3.7A)
 1.20A 2vqyA-5c9lA:
undetectable		 2vqyA-5c9lA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_B_BEZB261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 5c9l PLL LECTIN
(Photorhabdus
luminescens) 		4 / 8 ASN A 130
ILE A 183
TRP A 207
ARG A 134
 None
None
None
CA  A 403 ( 4.9A)
 1.34A 3ccfB-5c9lA:
undetectable		 3ccfB-5c9lA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5c9l PLL LECTIN
(Photorhabdus
luminescens) 		5 / 12 GLN A 211
PHE A 186
VAL A 233
LEU A 231
ILE A 245
 None
 1.21A 3elzA-5c9lA:
2.0		 3elzA-5c9lA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_A_GAIA407_0
(PROTEIN (ARGINASE))		 5c9l PLL LECTIN
(Photorhabdus
luminescens) 		4 / 6 ARG A 134
HIS A 155
LEU A 129
ASP A 132
 CA  A 403 ( 4.9A)
CA  A 404 (-3.4A)
None
CA  A 403 (-3.5A)
 1.45A 4cevA-5c9lA:
undetectable
4cevB-5c9lA:
undetectable		 4cevA-5c9lA:
22.60
4cevB-5c9lA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_A_GAIA407_0
(PROTEIN (ARGINASE))		 5c9l PLL LECTIN
(Photorhabdus
luminescens) 		4 / 6 ARG A 182
HIS A 203
LEU A 177
ASP A 180
 None
CA  A 403 (-3.3A)
None
None
 1.45A 4cevA-5c9lA:
undetectable
4cevB-5c9lA:
undetectable		 4cevA-5c9lA:
22.60
4cevB-5c9lA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_F_GAIF411_0
(PROTEIN (ARGINASE))		 5c9l PLL LECTIN
(Photorhabdus
luminescens) 		4 / 6 ARG A 182
HIS A 203
LEU A 177
ASP A 180
 None
CA  A 403 (-3.3A)
None
None
 1.45A 4cevE-5c9lA:
undetectable
4cevF-5c9lA:
undetectable		 4cevE-5c9lA:
22.60
4cevF-5c9lA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_B_HFGB1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 5c9l PLL LECTIN
(Photorhabdus
luminescens) 		5 / 12 LEU A  98
VAL A 137
PRO A 125
THR A 317
GLY A  26
 None
 1.33A 4hvcB-5c9lA:
undetectable		 4hvcB-5c9lA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5c9l PLL LECTIN
(Photorhabdus
luminescens) 		5 / 12 ILE A 265
PHE A 234
ALA A 271
SER A 171
ILE A  22
 None
 1.36A 5iwuA-5c9lA:
4.0		 5iwuA-5c9lA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_A_HFGA1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 5c9l PLL LECTIN
(Photorhabdus
luminescens) 		5 / 12 LEU A  98
VAL A 137
PRO A 125
THR A 317
GLY A  26
 None
 1.32A 5xiqA-5c9lA:
undetectable		 5xiqA-5c9lA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 5c9l PLL LECTIN
(Photorhabdus
luminescens) 		5 / 12 LEU A  98
VAL A 137
PRO A 125
THR A 317
GLY A  26
 None
 1.35A 5xiqD-5c9lA:
undetectable		 5xiqD-5c9lA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN8_A_HFGA603_0
(UNCHARACTERIZED
PROTEIN)		 5c9l PLL LECTIN
(Photorhabdus
luminescens) 		5 / 12 LEU A  98
VAL A 137
PRO A 125
THR A 317
GLY A  26
 None
 1.42A 6mn8A-5c9lA:
undetectable		 6mn8A-5c9lA:
21.05