SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cag'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_3
(PHOSPHOLIPASE A2)		 5cag UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 12 GLY A  63
LYS A  59
PRO A  58
PHE A  56
SER A  85
 None
 1.25A 3bjwF-5cagA:
undetectable		 3bjwF-5cagA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5cag UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 7 PHE A 220
GLU A 156
SER A 157
VAL A 134
 None
 1.32A 3dqtA-5cagA:
undetectable
3dqtB-5cagA:
undetectable		 3dqtA-5cagA:
21.51
3dqtB-5cagA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		 5cag UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 9 TYR A  84
PRO A  58
VAL A  79
TYR A  57
ILE A  55
 None
 1.17A 3p4wA-5cagA:
undetectable		 3p4wA-5cagA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_1
(N-METHYLTRANSFERASE)		 5cag UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		3 / 3 TYR A  69
TYR A  89
GLU A  50
 None
 0.91A 3pfgA-5cagA:
undetectable		 3pfgA-5cagA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)		 5cag UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 12 ILE A 264
ILE A 298
VAL A 166
LEU A 273
PHE A 164
 None
 0.74A 4y0pA-5cagA:
undetectable		 4y0pA-5cagA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADL_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 5cag UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 7 PHE A 220
GLU A 156
SER A 157
VAL A 134
 None
 1.26A 5adlA-5cagA:
undetectable
5adlB-5cagA:
undetectable		 5adlA-5cagA:
20.08
5adlB-5cagA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 5cag UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		3 / 3 THR A 106
SER A 103
ASP A 138
 None
 0.79A 5kvaA-5cagA:
undetectable		 5kvaA-5cagA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_C_PFLC407_1
(PROTON-GATED ION
CHANNEL)		 5cag UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 9 TYR A  84
PRO A  58
VAL A  79
TYR A  57
ILE A  55
 None
 1.17A 5mvnC-5cagA:
undetectable		 5mvnC-5cagA:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 5cag UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 10 TYR A  84
PRO A  58
VAL A  79
TYR A  57
ILE A  55
 None
 1.18A 5mvnD-5cagA:
undetectable		 5mvnD-5cagA:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_A_PFLA412_1
(PROTON-GATED ION
CHANNEL)		 5cag UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 10 TYR A  84
PRO A  58
VAL A  79
TYR A  57
ILE A  55
 None
 1.24A 5mzrA-5cagA:
undetectable		 5mzrA-5cagA:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_C_PFLC409_1
(PROTON-GATED ION
CHANNEL)		 5cag UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 10 TYR A  84
PRO A  58
VAL A  79
TYR A  57
ILE A  55
 None
 1.24A 5mzrC-5cagA:
undetectable		 5mzrC-5cagA:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 5cag UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 5 ALA A 168
VAL A 166
PHE A 252
ILE A 264
 None
 0.69A 5of1A-5cagA:
undetectable		 5of1A-5cagA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_B_SALB301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 5cag UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 5 ALA A 168
VAL A 166
PHE A 252
ILE A 264
 None
 0.70A 5of1B-5cagA:
undetectable		 5of1B-5cagA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5cag UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 7 PHE A 220
GLU A 156
SER A 157
VAL A 134
 None
 1.30A 5vvnA-5cagA:
undetectable
5vvnB-5cagA:
undetectable		 5vvnA-5cagA:
20.08
5vvnB-5cagA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5cag UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 7 PHE A 220
GLU A 156
SER A 157
VAL A 134
 None
 1.34A 6av6C-5cagA:
undetectable
6av6D-5cagA:
undetectable		 6av6C-5cagA:
12.50
6av6D-5cagA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		 5cag UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 7 PHE A 204
SER A 180
GLY A 179
VAL A 177
 None
 0.95A 6ekzA-5cagA:
undetectable		 6ekzA-5cagA:
13.46