SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5caw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QEI_A_CXXA802_1 (TRANSPORTER)	5caw	E3 UBIQUITIN-PROTEIN LIGASE PARKIN (Pediculus humanus)	4 / 6	ARG A 258 PHE A 253 ILE A 300 PHE A 266	SO4 A1009 (-3.2A) None None None	1.25A	2qeiA-5cawA: undetectable	2qeiA-5cawA: 20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ELZ_B_CHDB153_0 (ILEAL BILE ACID-BINDING PROTEIN)	5caw	E3 UBIQUITIN-PROTEIN LIGASE PARKIN (Pediculus humanus)	4 / 6	THR A 288 PHE A 306 PHE A 266 TYR A 269	None	1.32A	3elzB-5cawA: undetectable	3elzB-5cawA: 18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WG7_P_CHDP306_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5caw	E3 UBIQUITIN-PROTEIN LIGASE PARKIN (Pediculus humanus)	4 / 6	LEU A 308 PHE A 306 PHE A 266 LEU A 251	None	1.03A	3wg7P-5cawA: undetectable 3wg7W-5cawA: undetectable	3wg7P-5cawA: 17.70 3wg7W-5cawA: 12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X1B_P_CHDP305_0 (CYTOCHROME C OXIDASE SUBUNIT 3)	5caw	E3 UBIQUITIN-PROTEIN LIGASE PARKIN (Pediculus humanus)	4 / 5	LEU A 308 PHE A 306 PHE A 266 LEU A 251	None	1.02A	5x1bP-5cawA: undetectable	5x1bP-5cawA: 17.70

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2QEI_A_CXXA802_1","TRANSPORTER","5caw","E3 UBIQUITIN-PROTEIN LIGASE PARKIN","Pediculus humanus",4,"ARG A 258;PHE A 253;ILE A 300;PHE A 266","SO4 A1009 (-3.2A);None;None;None","1.25A","2qeiA-5cawA:undetectable","2qeiA-5cawA:20.23"],["3ELZ_B_CHDB153_0","ILEAL BILE ACID-BINDING PROTEIN","5caw","E3 UBIQUITIN-PROTEIN LIGASE PARKIN","Pediculus humanus",4,"THR A 288;PHE A 306;PHE A 266;TYR A 269","None","1.32A","3elzB-5cawA:undetectable","3elzB-5cawA:18.07"],["3WG7_P_CHDP306_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5caw","E3 UBIQUITIN-PROTEIN LIGASE PARKIN","Pediculus humanus",4,"LEU A 308;PHE A 306;PHE A 266;LEU A 251","None","1.03A","3wg7P-5cawA:undetectable;3wg7W-5cawA:undetectable","3wg7P-5cawA:17.70;3wg7W-5cawA:12.27"],["5X1B_P_CHDP305_0","CYTOCHROME C OXIDASE SUBUNIT 3","5caw","E3 UBIQUITIN-PROTEIN LIGASE PARKIN","Pediculus humanus",4,"LEU A 308;PHE A 306;PHE A 266;LEU A 251","None","1.02A","5x1bP-5cawA:undetectable","5x1bP-5cawA:17.70"]]