SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cay'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 6 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 1.01A 1dz4A-5cayG:
undetectable		 1dz4A-5cayG:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 6 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 1.01A 1dz4B-5cayG:
undetectable		 1dz4B-5cayG:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 8 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.98A 1dz9A-5cayG:
undetectable		 1dz9A-5cayG:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 8 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 1.00A 1o76B-5cayG:
undetectable		 1o76B-5cayG:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 7 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 1.00A 1t85A-5cayG:
undetectable		 1t85A-5cayG:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 7 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.98A 1t87A-5cayG:
undetectable		 1t87A-5cayG:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 5 PHE G 275
LEU G 409
VAL G 412
VAL G 357
 None
 1.11A 1t88B-5cayG:
undetectable		 1t88B-5cayG:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 5 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.96A 1t88B-5cayG:
undetectable		 1t88B-5cayG:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 8 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.97A 1uyuA-5cayG:
undetectable		 1uyuA-5cayG:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 7 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.95A 1yrcA-5cayG:
undetectable		 1yrcA-5cayG:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 7 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.95A 1yrdA-5cayG:
undetectable		 1yrdA-5cayG:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 7 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.99A 2cppA-5cayG:
undetectable		 2cppA-5cayG:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 6 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.93A 2feuA-5cayG:
undetectable		 2feuA-5cayG:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 7 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.93A 2feuB-5cayG:
undetectable		 2feuB-5cayG:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 5 PHE G 275
LEU G 409
VAL G 412
VAL G 357
 None
 1.16A 2m56A-5cayG:
undetectable		 2m56A-5cayG:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 5 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.98A 2m56A-5cayG:
undetectable		 2m56A-5cayG:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBL_A_CAMA517_0
(CYTOCHROME P450-CAM)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 7 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.94A 2qblA-5cayG:
undetectable		 2qblA-5cayG:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1499_1
(CYTOCHROME P450 3A4)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 5 PHE G 400
SER G 465
PHE G  94
ILE G 298
 None
 1.30A 2v0mD-5cayG:
undetectable		 2v0mD-5cayG:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 6 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 1.05A 2zawA-5cayG:
undetectable		 2zawA-5cayG:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAX_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 7 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.98A 2zaxA-5cayG:
undetectable		 2zaxA-5cayG:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 6 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 1.01A 2zuhA-5cayG:
undetectable		 2zuhA-5cayG:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 6 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 1.00A 2zuiA-5cayG:
undetectable		 2zuiA-5cayG:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 7 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.96A 2zwtA-5cayG:
undetectable		 2zwtA-5cayG:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 7 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.97A 2zwuA-5cayG:
undetectable		 2zwuA-5cayG:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_0
(N,N-DIMETHYLTRANSFER
ASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		5 / 12 ALA G 282
GLY G 279
LEU G 301
SER G 465
TYR G 287
 None
 1.31A 3bxoA-5cayG:
undetectable		 3bxoA-5cayG:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_0
(N,N-DIMETHYLTRANSFER
ASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		5 / 12 ALA G 282
GLY G 279
LEU G 301
SER G 465
TYR G 287
 None
 1.38A 3bxoB-5cayG:
undetectable		 3bxoB-5cayG:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 7 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.94A 3fwfA-5cayG:
undetectable		 3fwfA-5cayG:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 7 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.92A 3fwfB-5cayG:
undetectable		 3fwfB-5cayG:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 6 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.95A 3fwgA-5cayG:
undetectable		 3fwgA-5cayG:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 7 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.98A 3fwgB-5cayG:
undetectable		 3fwgB-5cayG:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 7 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.99A 3fwiA-5cayG:
undetectable		 3fwiA-5cayG:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 7 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.94A 3fwjA-5cayG:
undetectable		 3fwjA-5cayG:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 7 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.94A 3l63A-5cayG:
undetectable		 3l63A-5cayG:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_B_LOCB502_1
(TUBULIN BETA CHAIN)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		6 / 12 ALA G 282
LYS G 303
LEU G 301
ASN G 302
ILE G 298
ILE G 466
 None
None
None
NAG  G 610 (-3.3A)
None
None
 1.44A 3ut5B-5cayG:
undetectable		 3ut5B-5cayG:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 7 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.95A 3wrhA-5cayG:
undetectable		 3wrhA-5cayG:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 6 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.94A 3wrhE-5cayG:
undetectable		 3wrhE-5cayG:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 7 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.97A 3wrjA-5cayG:
undetectable		 3wrjA-5cayG:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 6 PHE G 275
LEU G 409
VAL G 412
VAL G 357
 None
 1.13A 3wrjE-5cayG:
undetectable		 3wrjE-5cayG:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 6 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.93A 3wrjE-5cayG:
undetectable		 3wrjE-5cayG:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 7 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.95A 3wrlA-5cayG:
undetectable		 3wrlA-5cayG:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 7 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.91A 3wrlE-5cayG:
undetectable		 3wrlE-5cayG:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 7 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.95A 3wrmA-5cayG:
undetectable		 3wrmA-5cayG:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 7 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.95A 3wrmF-5cayG:
undetectable		 3wrmF-5cayG:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 6 PHE G 275
LEU G 409
VAL G 412
VAL G 357
 None
 1.10A 4ek1A-5cayG:
undetectable		 4ek1A-5cayG:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 6 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.95A 4ek1A-5cayG:
undetectable		 4ek1A-5cayG:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 6 PHE G 275
LEU G 409
VAL G 412
VAL G 357
 None
 1.06A 4g3rA-5cayG:
undetectable		 4g3rA-5cayG:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 6 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.96A 4g3rA-5cayG:
undetectable		 4g3rA-5cayG:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 6 PHE G 275
LEU G 409
VAL G 412
VAL G 357
 None
 1.09A 4g3rB-5cayG:
undetectable		 4g3rB-5cayG:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 6 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.97A 4g3rB-5cayG:
undetectable		 4g3rB-5cayG:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTP_A_ASCA802_0
(RRNA N-GLYCOSIDASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 5 TYR G 287
ILE G 288
ASN G 302
ILE G 299
 None
None
NAG  G 610 (-3.3A)
None
 0.98A 4jtpA-5cayG:
undetectable		 4jtpA-5cayG:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 6 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 1.06A 4kkyX-5cayG:
undetectable		 4kkyX-5cayG:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 5 PHE G 275
LEU G 409
VAL G 412
VAL G 357
 None
 1.10A 4l49A-5cayG:
undetectable		 4l49A-5cayG:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 5 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.99A 4l49A-5cayG:
undetectable		 4l49A-5cayG:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 8 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.97A 4l4aA-5cayG:
undetectable		 4l4aA-5cayG:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 6 PHE G 275
LEU G 409
VAL G 412
VAL G 357
 None
 1.06A 4l4cA-5cayG:
undetectable		 4l4cA-5cayG:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 6 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 1.00A 4l4cA-5cayG:
undetectable		 4l4cA-5cayG:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4D_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 8 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.96A 4l4dA-5cayG:
undetectable		 4l4dA-5cayG:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 7 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 1.04A 4l4gA-5cayG:
undetectable		 4l4gA-5cayG:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 7 PHE G 482
LEU G 301
VAL G 357
VAL G 412
 None
 0.97A 5wk9A-5cayG:
undetectable		 5wk9A-5cayG:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEC_C_RBTC601_1
(SCAFFOLD PROTEIN D13)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		5 / 12 VAL G 463
PHE G 275
PHE G 346
ILE G 379
PHE G 378
 None
 1.37A 6becA-5cayG:
undetectable
6becB-5cayG:
undetectable
6becC-5cayG:
undetectable		 6becA-5cayG:
18.74
6becB-5cayG:
18.74
6becC-5cayG:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_A_ACRA602_2
(-)		 5cay ENVELOPE
GLYCOPROTEIN GP120
CORE FROM ST STRAIN
OF HIV-2
(Human
immunodeficiency
virus
2) 		4 / 6 TRP G 343
HIS G 433
ASN G 404
GLU G 383
 None
None
NAG  G 608 (-1.9A)
NAG  G 608 (-3.2A)
 1.41A 6gneA-5cayG:
undetectable		 6gneA-5cayG:
20.35