SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cb0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QBN_A_CAMA442_0 (CYTOCHROME P450-CAM)	5cb0	UNIVERSAL STRESS PROTEIN E (Escherichia coli)	4 / 7	TYR A 304 THR A 306 VAL A 112 VAL A 142	None	1.00A	2qbnA-5cb0A: undetectable	2qbnA-5cb0A: 21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QBN_A_CAMA442_0 (CYTOCHROME P450-CAM)	5cb0	UNIVERSAL STRESS PROTEIN E (Escherichia coli)	4 / 7	TYR A 304 THR A 306 VAL A 142 VAL A 298	None	0.99A	2qbnA-5cb0A: undetectable	2qbnA-5cb0A: 21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WEK_A_DIFA1375_1 (ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2)	5cb0	UNIVERSAL STRESS PROTEIN E (Escherichia coli)	3 / 3	LEU A 27 TYR A 26 GLN A 29	None Z6X A 401 ( 4.0A) None	0.73A	2wekA-5cb0A: 2.3	2wekA-5cb0A: 22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OKX_A_SAMA201_0 (YAEB-LIKE PROTEIN RPA0152)	5cb0	UNIVERSAL STRESS PROTEIN E (Escherichia coli)	5 / 12	LEU A 232 HIS A 169 LEU A 176 GLY A 269 LEU A 194	None	1.37A	3okxA-5cb0A: undetectable	3okxA-5cb0A: 18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EK1_B_CAMB502_0 (CAMPHOR 5-MONOOXYGENASE)	5cb0	UNIVERSAL STRESS PROTEIN E (Escherichia coli)	5 / 9	TYR A 304 THR A 306 THR A 270 VAL A 142 VAL A 298	None	1.24A	4ek1B-5cb0A: undetectable	4ek1B-5cb0A: 20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KLA_B_CHDB501_0 (FERROCHELATASE, MITOCHONDRIAL)	5cb0	UNIVERSAL STRESS PROTEIN E (Escherichia coli)	4 / 5	MET A 7 ARG A 22 ARG A 23 PRO A 141	None None Z6X A 401 ( 4.1A) None	1.17A	4klaB-5cb0A: 3.0	4klaB-5cb0A: 23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YFB_C_PACC601_0 (PROTEIN RELATED TO PENICILLIN ACYLASE)	5cb0	UNIVERSAL STRESS PROTEIN E (Escherichia coli)	5 / 12	SER A 140 PRO A 139 GLN A 102 ILE A 105 VAL A 112	None	1.42A	4yfbC-5cb0A: undetectable	4yfbC-5cb0A: 18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZJ8_A_SUVA2001_2 (HUMAN OX1R FUSION PROTEIN TO P.ABYSII GLYCOGEN SYNTHASE)	5cb0	UNIVERSAL STRESS PROTEIN E (Escherichia coli)	4 / 6	TRP A 150 ILE A 265 HIS A 244 ILE A 238	Z6X A 401 (-4.0A) Z6X A 401 ( 4.1A) None None	0.97A	4zj8A-5cb0A: undetectable	4zj8A-5cb0A: 17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BYK_A_OAQA302_0 (SULFOTRANSFERASE)	5cb0	UNIVERSAL STRESS PROTEIN E (Escherichia coli)	5 / 12	ILE A 289 LEU A 281 VAL A 142 LEU A 292 THR A 270	None	1.20A	5bykA-5cb0A: undetectable	5bykA-5cb0A: 21.96

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2QBN_A_CAMA442_0","CYTOCHROME P450-CAM","5cb0","UNIVERSAL STRESS PROTEIN E","Escherichia coli",4,"TYR A 304;THR A 306;VAL A 112;VAL A 142","None","1.00A","2qbnA-5cb0A:undetectable","2qbnA-5cb0A:21.49"],["2QBN_A_CAMA442_0","CYTOCHROME P450-CAM","5cb0","UNIVERSAL STRESS PROTEIN E","Escherichia coli",4,"TYR A 304;THR A 306;VAL A 142;VAL A 298","None","0.99A","2qbnA-5cb0A:undetectable","2qbnA-5cb0A:21.49"],["2WEK_A_DIFA1375_1","ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2","5cb0","UNIVERSAL STRESS PROTEIN E","Escherichia coli",3,"LEU A  27;TYR A  26;GLN A  29","None;Z6X A 401 ( 4.0A);None","0.73A","2wekA-5cb0A:2.3","2wekA-5cb0A:22.16"],["3OKX_A_SAMA201_0","YAEB-LIKE PROTEIN RPA0152","5cb0","UNIVERSAL STRESS PROTEIN E","Escherichia coli",5,"LEU A 232;HIS A 169;LEU A 176;GLY A 269;LEU A 194","None","1.37A","3okxA-5cb0A:undetectable","3okxA-5cb0A:18.30"],["4EK1_B_CAMB502_0","CAMPHOR 5-MONOOXYGENASE","5cb0","UNIVERSAL STRESS PROTEIN E","Escherichia coli",5,"TYR A 304;THR A 306;THR A 270;VAL A 142;VAL A 298","None","1.24A","4ek1B-5cb0A:undetectable","4ek1B-5cb0A:20.62"],["4KLA_B_CHDB501_0","FERROCHELATASE, MITOCHONDRIAL","5cb0","UNIVERSAL STRESS PROTEIN E","Escherichia coli",4,"MET A   7;ARG A  22;ARG A  23;PRO A 141","None;None;Z6X A 401 ( 4.1A);None","1.17A","4klaB-5cb0A:3.0","4klaB-5cb0A:23.88"],["4YFB_C_PACC601_0","PROTEIN RELATED TO PENICILLIN ACYLASE","5cb0","UNIVERSAL STRESS PROTEIN E","Escherichia coli",5,"SER A 140;PRO A 139;GLN A 102;ILE A 105;VAL A 112","None","1.42A","4yfbC-5cb0A:undetectable","4yfbC-5cb0A:18.61"],["4ZJ8_A_SUVA2001_2","HUMAN OX1R FUSION PROTEIN TO P.ABYSII GLYCOGEN SYNTHASE","5cb0","UNIVERSAL STRESS PROTEIN E","Escherichia coli",4,"TRP A 150;ILE A 265;HIS A 244;ILE A 238","Z6X A 401 (-4.0A);Z6X A 401 ( 4.1A);None;None","0.97A","4zj8A-5cb0A:undetectable","4zj8A-5cb0A:17.54"],["5BYK_A_OAQA302_0","SULFOTRANSFERASE","5cb0","UNIVERSAL STRESS PROTEIN E","Escherichia coli",5,"ILE A 289;LEU A 281;VAL A 142;LEU A 292;THR A 270","None","1.20A","5bykA-5cb0A:undetectable","5bykA-5cb0A:21.96"]]