SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cb2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_2
(ADENOSINE DEAMINASE)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		4 / 5 LEU A 236
SER A 148
LEU A 144
GLY A 185
 None
 1.08A 1a4lB-5cb2A:
undetectable		 1a4lB-5cb2A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKE_A_HSMA190_1
(NITROPHORIN 4)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		3 / 3 ASP A 442
LEU A 435
LEU A 439
 None
 0.60A 1ikeA-5cb2A:
undetectable		 1ikeA-5cb2A:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NHZ_A_486A800_1
(GLUCOCORTICOID
RECEPTOR)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		5 / 12 ASN A 267
GLY A 270
VAL A 274
LEU A 200
LEU A  75
 None
 1.21A 1nhzA-5cb2A:
undetectable		 1nhzA-5cb2A:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_D_FOLD617_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		5 / 12 VAL A  85
ASP A 123
LEU A  75
ILE A 266
THR A  95
 GNP  A 702 (-3.4A)
MG  A 701 ( 3.8A)
None
None
MG  A 701 ( 3.1A)
 1.15A 1qzfD-5cb2A:
undetectable		 1qzfD-5cb2A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RV7_B_AB1B1001_1
(PROTEASE)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		5 / 11 THR A 108
VAL A 274
PRO A  51
ALA A  52
VAL A  54
 None
 1.12A 1rv7A-5cb2A:
undetectable
1rv7B-5cb2A:
undetectable		 1rv7A-5cb2A:
10.20
1rv7B-5cb2A:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		5 / 12 LEU A 153
VAL A 152
ILE A  61
VAL A 202
LEU A 269
 None
 1.10A 1s19A-5cb2A:
undetectable		 1s19A-5cb2A:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		4 / 7 PHE A  38
MET A 122
VAL A 121
SER A  62
 None
 1.06A 1wrlA-5cb2A:
undetectable
1wrlB-5cb2A:
undetectable		 1wrlA-5cb2A:
8.51
1wrlB-5cb2A:
8.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA802_1
(TRANSPORTER)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		4 / 7 ILE A  60
SER A  62
PHE A 145
ILE A  32
 None
 1.02A 2q6hA-5cb2A:
undetectable		 2q6hA-5cb2A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA802_1
(TRANSPORTER)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		4 / 7 ILE A  60
SER A  62
PHE A 145
ILE A  32
 None
 1.02A 2qb4A-5cb2A:
2.0		 2qb4A-5cb2A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		5 / 12 LEU A 153
VAL A 152
SER A 150
VAL A 202
LEU A 269
 None
 1.14A 2zlcA-5cb2A:
undetectable		 2zlcA-5cb2A:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M7R_A_VDXA425_1
(VITAMIN D3 RECEPTOR)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		5 / 12 LEU A 153
VAL A 152
SER A 150
VAL A 202
LEU A  78
 None
 1.27A 3m7rA-5cb2A:
undetectable		 3m7rA-5cb2A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_2
(ADENOSINE KINASE,
PUTATIVE)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		4 / 5 LEU A 269
GLY A 270
PHE A 262
ASN A  80
 None
 1.31A 3uq6B-5cb2A:
undetectable		 3uq6B-5cb2A:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F3T_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		4 / 4 PHE A 579
VAL A 675
ALA A 603
PHE A 671
 None
 1.46A 4f3tA-5cb2A:
undetectable		 4f3tA-5cb2A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_C_IPHC101_0
(INSULIN)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		5 / 11 LEU A 273
LEU A  78
VAL A 202
HIS A 250
LEU A 252
 None
 1.09A 4p65C-5cb2A:
undetectable
4p65D-5cb2A:
undetectable
4p65J-5cb2A:
undetectable
4p65L-5cb2A:
undetectable		 4p65C-5cb2A:
4.32
4p65D-5cb2A:
4.01
4p65J-5cb2A:
4.01
4p65L-5cb2A:
4.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_C_3CJC607_1
(LACTOPEROXIDASE)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		4 / 6 GLN A 572
ASP A 576
GLU A 674
ARG A 580
 None
 1.36A 4qyqC-5cb2A:
undetectable		 4qyqC-5cb2A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		4 / 4 PHE A 579
VAL A 675
ALA A 603
PHE A 671
 None
 1.46A 4w5qA-5cb2A:
undetectable		 4w5qA-5cb2A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRZ_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		4 / 8 GLY A 167
GLN A 166
SER A  66
ASN A 169
 None
 1.03A 4wrzA-5cb2A:
undetectable		 4wrzA-5cb2A:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS0_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		4 / 7 GLY A 167
GLN A 166
SER A  66
ASN A 169
 None
 1.07A 4ws0A-5cb2A:
undetectable		 4ws0A-5cb2A:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_A_ACTA401_0
(PROTON-GATED ION
CHANNEL)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		4 / 6 ILE A 119
PHE A 280
ILE A  60
GLU A 151
 None
 1.34A 4zzcA-5cb2A:
undetectable
4zzcB-5cb2A:
5.8		 4zzcA-5cb2A:
19.01
4zzcB-5cb2A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_B_ACTB401_0
(PROTON-GATED ION
CHANNEL)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		4 / 6 ILE A 119
PHE A 280
ILE A  60
GLU A 151
 None
 1.28A 4zzcB-5cb2A:
5.8
4zzcC-5cb2A:
3.9		 4zzcB-5cb2A:
19.01
4zzcC-5cb2A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_0
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		5 / 12 LEU A  78
ASP A  84
ASN A  82
PHE A  83
VAL A 121
 None
 1.13A 5d0yA-5cb2A:
3.5		 5d0yA-5cb2A:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_B_FOLB201_0
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		5 / 12 LEU A  78
ASP A  84
ASN A  82
PHE A  83
VAL A 121
 None
 1.11A 5d0yB-5cb2A:
3.7		 5d0yB-5cb2A:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		3 / 3 GLU A 125
TRP A  99
ASN A  35
 None
 0.89A 5dv4A-5cb2A:
undetectable		 5dv4A-5cb2A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPW_C_3CJC609_1
(LACTOPEROXIDASE)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		4 / 6 GLN A 572
ASP A 576
GLU A 674
ARG A 580
 None
 1.36A 5hpwC-5cb2A:
undetectable		 5hpwC-5cb2A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_I_IPHI101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		4 / 6 VAL A 202
HIS A 250
LEU A 252
LEU A  78
 None
 1.00A 5hrqB-5cb2A:
undetectable
5hrqI-5cb2A:
undetectable
5hrqJ-5cb2A:
undetectable		 5hrqB-5cb2A:
4.46
5hrqI-5cb2A:
4.32
5hrqJ-5cb2A:
4.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_B_ACTB713_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		3 / 3 GLY A  65
GLN A 161
LYS A  71
 None
None
GNP  A 702 (-3.7A)
 0.92A 5imsB-5cb2A:
3.6		 5imsB-5cb2A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		4 / 4 PHE A 579
VAL A 675
ALA A 603
PHE A 671
 None
 1.45A 5ki6A-5cb2A:
undetectable		 5ki6A-5cb2A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		4 / 7 THR A  69
LEU A 172
GLN A 315
GLU A 134
 GNP  A 702 (-4.4A)
None
None
None
 1.09A 5tudA-5cb2A:
4.8		 5tudA-5cb2A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		4 / 5 LEU A 435
PHE A 416
LEU A 420
PHE A 428
 None
 1.00A 5x19C-5cb2A:
3.0
5x19J-5cb2A:
undetectable		 5x19C-5cb2A:
15.17
5x19J-5cb2A:
5.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_2
(-)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		4 / 8 VAL A 197
TRP A 293
TYR A 296
GLU A 190
 None
 1.02A 6gneB-5cb2A:
undetectable		 6gneB-5cb2A:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_A_LLLA301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		4 / 6 ASP A 361
GLU A 368
ASP A 369
GLU A 334
 None
 1.15A 6mn5A-5cb2A:
undetectable		 6mn5A-5cb2A:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_B_LLLB301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		4 / 7 ASP A 361
GLU A 368
ASP A 369
GLU A 334
 None
 1.28A 6mn5B-5cb2A:
undetectable		 6mn5B-5cb2A:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_C_LLLC301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		4 / 6 ASP A 361
GLU A 368
ASP A 369
GLU A 334
 None
 1.17A 6mn5C-5cb2A:
undetectable		 6mn5C-5cb2A:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_D_LLLD301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		4 / 6 ASP A 361
GLU A 368
ASP A 369
GLU A 334
 None
 1.23A 6mn5D-5cb2A:
undetectable		 6mn5D-5cb2A:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_1
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 5cb2 PROTEIN SEY1
(Candida
albicans) 		3 / 3 ASP A 459
SER A 448
SER A 451
 None
 0.66A 6mxtA-5cb2A:
undetectable		 6mxtA-5cb2A:
21.72