SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cb5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7B_B_BEZB1529_0
(BENZOATE-COENZYME A
LIGASE)		 5cb5 O-ACETYL-ADP-RIBOSE
DEACETYLASE
(Escherichia
coli) 		5 / 9 ALA R  24
ALA R 100
GLY R  63
GLY R  83
ILE R 121
 None
 1.21A 2v7bB-5cb5R:
undetectable		 2v7bB-5cb5R:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 5cb5 O-ACETYL-ADP-RIBOSE
DEACETYLASE
(Escherichia
coli) 		5 / 12 PRO R 151
ILE R  67
LEU R 105
VAL R 116
ILE R  20
 None
 1.05A 5tiwB-5cb5R:
undetectable		 5tiwB-5cb5R:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 5cb5 O-ACETYL-ADP-RIBOSE
DEACETYLASE
(Escherichia
coli) 		4 / 7 ALA R  37
GLY R  33
GLY R  31
THR R  13
 APR  R 201 ( 3.8A)
APR  R 201 (-3.4A)
APR  R 201 (-3.6A)
None
 0.79A 5ybbB-5cb5R:
undetectable		 5ybbB-5cb5R:
14.68