SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cb7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GMK_C_DVAC8_0 (GRAMICIDIN A)	5cb7	OUTER CAPSID PROTEIN VP4 (Rotavirus A)	3 / 4	VAL A 199 TRP A 102 TRP A 167	None	1.19A	1gmkC-5cb7A: undetectable 1gmkD-5cb7A: undetectable	1gmkC-5cb7A: 10.99 1gmkD-5cb7A: 10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SG9_B_SAMB302_1 (HEMK PROTEIN)	5cb7	OUTER CAPSID PROTEIN VP4 (Rotavirus A)	3 / 3	ASP A 100 PHE A 103 ASN A 172	None	0.77A	1sg9B-5cb7A: undetectable	1sg9B-5cb7A: 18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VL2_A_BEZA1162_0 (PEROXIREDOXIN-5)	5cb7	OUTER CAPSID PROTEIN VP4 (Rotavirus A)	5 / 10	PRO A 161 THR A 181 PRO A 182 LEU A 164 GLY A 223	None	1.43A	2vl2A-5cb7A: undetectable 2vl2C-5cb7A: undetectable	2vl2A-5cb7A: 20.00 2vl2C-5cb7A: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JAY_A_SAMA1102_1 (STRUCTURAL PROTEIN VP3)	5cb7	OUTER CAPSID PROTEIN VP4 (Rotavirus A)	3 / 3	ARG A 170 ASP A 195 ASP A 171	None	0.82A	3jayA-5cb7A: undetectable	3jayA-5cb7A: 10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JB2_A_SAMA1102_1 (STRUCTURAL PROTEIN VP3)	5cb7	OUTER CAPSID PROTEIN VP4 (Rotavirus A)	3 / 3	ARG A 170 ASP A 195 ASP A 171	None	0.69A	3jb2A-5cb7A: undetectable	3jb2A-5cb7A: 10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JB3_A_SAMA1102_1 (STRUCTURAL PROTEIN VP3)	5cb7	OUTER CAPSID PROTEIN VP4 (Rotavirus A)	3 / 3	ARG A 170 ASP A 195 ASP A 171	None	0.66A	3jb3A-5cb7A: undetectable	3jb3A-5cb7A: 10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N8J_E_DVAE7_0 (GLY-DTY-GLY-DLE-DAL- DSG-DVA-DAS-DGL-DSN- DSN-GLY STREPTAVIDIN)	5cb7	OUTER CAPSID PROTEIN VP4 (Rotavirus A)	3 / 3	TYR A 175 SER A 187 TRP A 81	None	0.71A	5n8jB-5cb7A: undetectable	5n8jB-5cb7A: 22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N8J_O_DVAO7_0 (GLY-DTY-GLY-DLE-DAL- DSG-DVA-DAS-DGL-DSN- DSN-GLY STREPTAVIDIN)	5cb7	OUTER CAPSID PROTEIN VP4 (Rotavirus A)	3 / 3	TYR A 175 SER A 187 TRP A 81	None	0.71A	5n8jA-5cb7A: undetectable	5n8jA-5cb7A: 22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N8J_P_DVAP5_0 (GLY-DTY-GLY-DLE-DAL- DSG-DVA-DAS-DGL-DSN- DSN-GLY STREPTAVIDIN)	5cb7	OUTER CAPSID PROTEIN VP4 (Rotavirus A)	3 / 3	TYR A 175 SER A 187 TRP A 81	None	0.69A	5n8jD-5cb7A: undetectable	5n8jD-5cb7A: 22.04

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1GMK_C_DVAC8_0","GRAMICIDIN A","5cb7","OUTER CAPSID PROTEIN VP4","Rotavirus A",3,"VAL A 199;TRP A 102;TRP A 167","None","1.19A","1gmkC-5cb7A:undetectable;1gmkD-5cb7A:undetectable","1gmkC-5cb7A:10.99;1gmkD-5cb7A:10.99"],["1SG9_B_SAMB302_1","HEMK PROTEIN","5cb7","OUTER CAPSID PROTEIN VP4","Rotavirus A",3,"ASP A 100;PHE A 103;ASN A 172","None","0.77A","1sg9B-5cb7A:undetectable","1sg9B-5cb7A:18.57"],["2VL2_A_BEZA1162_0","PEROXIREDOXIN-5","5cb7","OUTER CAPSID PROTEIN VP4","Rotavirus A",5,"PRO A 161;THR A 181;PRO A 182;LEU A 164;GLY A 223","None","1.43A","2vl2A-5cb7A:undetectable;2vl2C-5cb7A:undetectable","2vl2A-5cb7A:20.00;2vl2C-5cb7A:20.00"],["3JAY_A_SAMA1102_1","STRUCTURAL PROTEIN VP3","5cb7","OUTER CAPSID PROTEIN VP4","Rotavirus A",3,"ARG A 170;ASP A 195;ASP A 171","None","0.82A","3jayA-5cb7A:undetectable","3jayA-5cb7A:10.77"],["3JB2_A_SAMA1102_1","STRUCTURAL PROTEIN VP3","5cb7","OUTER CAPSID PROTEIN VP4","Rotavirus A",3,"ARG A 170;ASP A 195;ASP A 171","None","0.69A","3jb2A-5cb7A:undetectable","3jb2A-5cb7A:10.77"],["3JB3_A_SAMA1102_1","STRUCTURAL PROTEIN VP3","5cb7","OUTER CAPSID PROTEIN VP4","Rotavirus A",3,"ARG A 170;ASP A 195;ASP A 171","None","0.66A","3jb3A-5cb7A:undetectable","3jb3A-5cb7A:10.77"],["5N8J_E_DVAE7_0","GLY-DTY-GLY-DLE-DAL-DSG-DVA-DAS-DGL-DSN-DSN-GLY;STREPTAVIDIN","5cb7","OUTER CAPSID PROTEIN VP4","Rotavirus A",3,"TYR A 175;SER A 187;TRP A  81","None","0.71A","5n8jB-5cb7A:undetectable","5n8jB-5cb7A:22.04"],["5N8J_O_DVAO7_0","GLY-DTY-GLY-DLE-DAL-DSG-DVA-DAS-DGL-DSN-DSN-GLY;STREPTAVIDIN","5cb7","OUTER CAPSID PROTEIN VP4","Rotavirus A",3,"TYR A 175;SER A 187;TRP A  81","None","0.71A","5n8jA-5cb7A:undetectable","5n8jA-5cb7A:22.04"],["5N8J_P_DVAP5_0","GLY-DTY-GLY-DLE-DAL-DSG-DVA-DAS-DGL-DSN-DSN-GLY;STREPTAVIDIN","5cb7","OUTER CAPSID PROTEIN VP4","Rotavirus A",3,"TYR A 175;SER A 187;TRP A  81","None","0.69A","5n8jD-5cb7A:undetectable","5n8jD-5cb7A:22.04"]]