SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cbk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)		 5cbk SHHTL5
(Striga
hermonthica) 		5 / 12 HIS A  24
MET A 181
ALA A  54
GLY A  53
HIS A   8
 None
 1.13A 1a4lD-5cbkA:
undetectable		 1a4lD-5cbkA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3009_0
(BETA-CARBONIC
ANHYDRASE)		 5cbk SHHTL5
(Striga
hermonthica) 		4 / 5 GLY A  27
LEU A 178
THR A 177
VAL A 161
 None
 0.84A 1ekjF-5cbkA:
undetectable
1ekjG-5cbkA:
undetectable		 1ekjF-5cbkA:
22.26
1ekjG-5cbkA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 5cbk SHHTL5
(Striga
hermonthica) 		4 / 8 ILE A  80
LEU A  77
PHE A  91
GLY A  93
 None
 0.98A 1os6A-5cbkA:
undetectable		 1os6A-5cbkA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J5M_A_ACTA1321_0
(CHLOROPEROXIDASE)		 5cbk SHHTL5
(Striga
hermonthica) 		4 / 6 LEU A 198
ILE A 106
VAL A 205
ALA A 102
 None
 1.09A 2j5mA-5cbkA:
undetectable		 2j5mA-5cbkA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_B_TOPB200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 5cbk SHHTL5
(Striga
hermonthica) 		5 / 12 ALA A 120
ASN A 231
LEU A 228
VAL A 220
TYR A 196
 None
 0.96A 3fl9B-5cbkA:
undetectable		 3fl9B-5cbkA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_G_TOPG200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 5cbk SHHTL5
(Striga
hermonthica) 		5 / 12 ALA A 120
ASN A 231
LEU A 228
VAL A 220
TYR A 196
 None
 1.01A 3fl9G-5cbkA:
undetectable		 3fl9G-5cbkA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 5cbk SHHTL5
(Striga
hermonthica) 		5 / 12 VAL A 139
CYH A 190
SER A 188
TYR A  62
MET A 154
 PE3  A 303 (-4.8A)
PE3  A 303 ( 4.1A)
None
None
None
 1.22A 3g8iA-5cbkA:
undetectable		 3g8iA-5cbkA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NHX_A_ASDA126_1
(STEROID
DELTA-ISOMERASE)		 5cbk SHHTL5
(Striga
hermonthica) 		5 / 12 TYR A 196
LEU A  70
SER A  98
VAL A 205
PHE A 232
 None
 1.27A 3nhxA-5cbkA:
undetectable		 3nhxA-5cbkA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGL_A_GLYA301_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 5cbk SHHTL5
(Striga
hermonthica) 		4 / 8 ALA A  54
GLY A  55
THR A  56
THR A 177
 None
 0.76A 3rglA-5cbkA:
undetectable		 3rglA-5cbkA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 5cbk SHHTL5
(Striga
hermonthica) 		4 / 8 ILE A  80
LEU A  77
PHE A  91
GLY A  93
 None
 1.00A 3selX-5cbkA:
undetectable		 3selX-5cbkA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 5cbk SHHTL5
(Striga
hermonthica) 		4 / 6 ILE A  80
LEU A  77
PHE A  91
GLY A  93
 None
 0.85A 3sj1X-5cbkA:
undetectable		 3sj1X-5cbkA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5cbk SHHTL5
(Striga
hermonthica) 		5 / 12 VAL A  21
ILE A 115
VAL A 205
ILE A 106
SER A  74
 None
 1.33A 4a84A-5cbkA:
undetectable		 4a84A-5cbkA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_A_IMNA701_1
(CYCLOOXYGENASE-2)		 5cbk SHHTL5
(Striga
hermonthica) 		5 / 12 LEU A  77
VAL A 103
GLY A 101
ALA A 102
SER A  98
 None
 1.15A 4coxA-5cbkA:
undetectable		 4coxA-5cbkA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_B_IMNB701_1
(CYCLOOXYGENASE-2)		 5cbk SHHTL5
(Striga
hermonthica) 		5 / 12 LEU A  77
VAL A 103
GLY A 101
ALA A 102
SER A  98
 None
 1.16A 4coxB-5cbkA:
undetectable		 4coxB-5cbkA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_D_IMND701_1
(CYCLOOXYGENASE-2)		 5cbk SHHTL5
(Striga
hermonthica) 		5 / 12 LEU A  77
VAL A 103
GLY A 101
ALA A 102
SER A  98
 None
 1.15A 4coxD-5cbkA:
undetectable		 4coxD-5cbkA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DXU_A_ACAA711_1
(LACTOTRANSFERRIN)		 5cbk SHHTL5
(Striga
hermonthica) 		4 / 6 GLY A 163
VAL A 162
GLY A 156
TYR A 157
 None
None
PE3  A 302 ( 3.8A)
None
 0.83A 4dxuA-5cbkA:
undetectable		 4dxuA-5cbkA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 5cbk SHHTL5
(Striga
hermonthica) 		4 / 7 ILE A  80
LEU A  77
PHE A  91
GLY A  93
 None
 0.88A 4hbfA-5cbkA:
undetectable		 4hbfA-5cbkA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 5cbk SHHTL5
(Striga
hermonthica) 		4 / 7 ILE A  80
LEU A  77
PHE A  91
GLY A  93
 None
 0.95A 4hc3A-5cbkA:
undetectable		 4hc3A-5cbkA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAJ_B_ACAB512_1
(HIV-1 YU2 GP120
ENVELOPE
GLYCOPROTEIN)		 5cbk SHHTL5
(Striga
hermonthica) 		4 / 6 ARG A 123
GLY A 132
ASP A 197
PRO A 122
 None
 1.09A 4lajA-5cbkA:
undetectable
4lajB-5cbkA:
undetectable		 4lajA-5cbkA:
20.69
4lajB-5cbkA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5cbk SHHTL5
(Striga
hermonthica) 		5 / 12 LEU A  77
VAL A 103
GLY A 101
ALA A 102
SER A  98
 None
 1.10A 4otyA-5cbkA:
undetectable		 4otyA-5cbkA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5cbk SHHTL5
(Striga
hermonthica) 		5 / 12 LEU A  70
VAL A 103
GLY A 101
ALA A 102
SER A  98
 None
 1.07A 4rrwA-5cbkA:
undetectable		 4rrwA-5cbkA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5cbk SHHTL5
(Striga
hermonthica) 		6 / 12 LEU A  70
LEU A  77
VAL A 103
GLY A 101
ALA A 102
SER A  98
 None
 1.17A 4rrwC-5cbkA:
undetectable		 4rrwC-5cbkA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5cbk SHHTL5
(Striga
hermonthica) 		5 / 12 LEU A  77
VAL A 103
GLY A 101
ALA A 102
SER A  98
 None
 1.05A 4rrwD-5cbkA:
undetectable		 4rrwD-5cbkA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_A_LURA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5cbk SHHTL5
(Striga
hermonthica) 		5 / 12 LEU A  77
VAL A 103
GLY A 101
ALA A 102
SER A  98
 None
 0.98A 4rrxA-5cbkA:
undetectable		 4rrxA-5cbkA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_B_LURB706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5cbk SHHTL5
(Striga
hermonthica) 		5 / 12 LEU A  77
VAL A 103
GLY A 101
ALA A 102
SER A  98
 None
 0.97A 4rrxB-5cbkA:
undetectable		 4rrxB-5cbkA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5cbk SHHTL5
(Striga
hermonthica) 		5 / 12 LEU A  70
VAL A 103
GLY A 101
ALA A 102
SER A  98
 None
 1.07A 4rrzA-5cbkA:
undetectable		 4rrzA-5cbkA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5cbk SHHTL5
(Striga
hermonthica) 		6 / 12 LEU A  70
LEU A  77
VAL A 103
GLY A 101
ALA A 102
SER A  98
 None
 1.17A 4rrzC-5cbkA:
undetectable		 4rrzC-5cbkA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5cbk SHHTL5
(Striga
hermonthica) 		5 / 12 LEU A  77
VAL A 103
GLY A 101
ALA A 102
SER A  98
 None
 1.05A 4rrzD-5cbkA:
undetectable		 4rrzD-5cbkA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UY8_7_TRP71002_0
(TRYPTOPHANASE)		 5cbk SHHTL5
(Striga
hermonthica) 		4 / 4 ILE A 261
ASN A 265
ILE A  90
VAL A  20
 None
 1.15A 4uy87-5cbkA:
undetectable		 4uy87-5cbkA:
6.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_C_PACC601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 5cbk SHHTL5
(Striga
hermonthica) 		5 / 12 SER A 251
PRO A 248
HIS A 246
VAL A 162
VAL A 161
 None
 1.35A 4yfbC-5cbkA:
undetectable		 4yfbC-5cbkA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_F_PACF601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 5cbk SHHTL5
(Striga
hermonthica) 		5 / 12 SER A 251
PRO A 248
HIS A 246
VAL A 162
VAL A 161
 None
 1.34A 4yfbF-5cbkA:
undetectable		 4yfbF-5cbkA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_I_PACI601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 5cbk SHHTL5
(Striga
hermonthica) 		5 / 12 SER A 251
PRO A 248
HIS A 246
VAL A 162
VAL A 161
 None
 1.34A 4yfbI-5cbkA:
undetectable		 4yfbI-5cbkA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YFB_L_PACL601_0
(PROTEIN RELATED TO
PENICILLIN ACYLASE)		 5cbk SHHTL5
(Striga
hermonthica) 		5 / 12 SER A 251
PRO A 248
HIS A 246
VAL A 162
VAL A 161
 None
 1.34A 4yfbL-5cbkA:
undetectable		 4yfbL-5cbkA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5cbk SHHTL5
(Striga
hermonthica) 		5 / 12 GLY A  16
LEU A  81
PHE A 112
GLY A 101
THR A  18
 None
 1.12A 4ze1A-5cbkA:
undetectable		 4ze1A-5cbkA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5cbk SHHTL5
(Striga
hermonthica) 		5 / 12 GLY A  16
LEU A  81
PHE A 112
GLY A 101
THR A  18
 None
 1.12A 5eskA-5cbkA:
undetectable		 5eskA-5cbkA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5cbk SHHTL5
(Striga
hermonthica) 		5 / 12 LEU A  77
VAL A 103
GLY A 101
ALA A 102
SER A  98
 None
 1.02A 5ikqA-5cbkA:
undetectable		 5ikqA-5cbkA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_B_JMSB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5cbk SHHTL5
(Striga
hermonthica) 		5 / 12 LEU A  77
VAL A 103
GLY A 101
ALA A 102
SER A  98
 None
 0.99A 5ikqB-5cbkA:
undetectable		 5ikqB-5cbkA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND4_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5cbk SHHTL5
(Striga
hermonthica) 		5 / 12 VAL A 205
ALA A 102
SER A 105
ARG A 123
LEU A  70
 None
 1.26A 5nd4B-5cbkA:
3.8		 5nd4B-5cbkA:
20.81