SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cc2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LWE_A_NVPA999_1 (HIV-1 REVERSE TRANSCRIPTASE)	5cc2	GLUTAMATE RECEPTOR IONOTROPIC, DELTA-2 (Rattus norvegicus)	4 / 7	LEU A 37 VAL A 16 TYR A 29 GLY A 31	None	0.85A	1lweA-5cc2A: undetectable	1lweA-5cc2A: 20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3THR_C_C2FC1410_0 (GLYCINE N-METHYLTRANSFERASE)	5cc2	GLUTAMATE RECEPTOR IONOTROPIC, DELTA-2 (Rattus norvegicus)	3 / 3	ARG A 112 PRO A 206 PHE A 210	None	0.98A	3thrC-5cc2A: undetectable	3thrC-5cc2A: 21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MM4_A_8PRA603_1 (TRANSPORTER)	5cc2	GLUTAMATE RECEPTOR IONOTROPIC, DELTA-2 (Rattus norvegicus)	5 / 12	ASP A 38 VAL A 7 TYR A 48 SER A 41 THR A 9	None None CL A 305 (-4.0A) None None	1.17A	4mm4A-5cc2A: undetectable	4mm4A-5cc2A: 17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MM4_B_8PRB603_1 (TRANSPORTER)	5cc2	GLUTAMATE RECEPTOR IONOTROPIC, DELTA-2 (Rattus norvegicus)	5 / 12	ASP A 38 VAL A 7 TYR A 48 SER A 41 THR A 9	None None CL A 305 (-4.0A) None None	1.17A	4mm4B-5cc2A: undetectable	4mm4B-5cc2A: 17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MM6_A_29EA603_1 (TRANSPORTER)	5cc2	GLUTAMATE RECEPTOR IONOTROPIC, DELTA-2 (Rattus norvegicus)	5 / 12	ASP A 38 VAL A 7 TYR A 48 SER A 41 THR A 9	None None CL A 305 (-4.0A) None None	1.14A	4mm6A-5cc2A: undetectable	4mm6A-5cc2A: 17.41

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1LWE_A_NVPA999_1","HIV-1 REVERSE TRANSCRIPTASE","5cc2","GLUTAMATE RECEPTOR IONOTROPIC, DELTA-2","Rattus norvegicus",4,"LEU A  37;VAL A  16;TYR A  29;GLY A  31","None","0.85A","1lweA-5cc2A:undetectable","1lweA-5cc2A:20.54"],["3THR_C_C2FC1410_0","GLYCINE N-METHYLTRANSFERASE","5cc2","GLUTAMATE RECEPTOR IONOTROPIC, DELTA-2","Rattus norvegicus",3,"ARG A 112;PRO A 206;PHE A 210","None","0.98A","3thrC-5cc2A:undetectable","3thrC-5cc2A:21.38"],["4MM4_A_8PRA603_1","TRANSPORTER","5cc2","GLUTAMATE RECEPTOR IONOTROPIC, DELTA-2","Rattus norvegicus",5,"ASP A  38;VAL A   7;TYR A  48;SER A  41;THR A   9","None;None; CL A 305 (-4.0A);None;None","1.17A","4mm4A-5cc2A:undetectable","4mm4A-5cc2A:17.41"],["4MM4_B_8PRB603_1","TRANSPORTER","5cc2","GLUTAMATE RECEPTOR IONOTROPIC, DELTA-2","Rattus norvegicus",5,"ASP A  38;VAL A   7;TYR A  48;SER A  41;THR A   9","None;None; CL A 305 (-4.0A);None;None","1.17A","4mm4B-5cc2A:undetectable","4mm4B-5cc2A:17.41"],["4MM6_A_29EA603_1","TRANSPORTER","5cc2","GLUTAMATE RECEPTOR IONOTROPIC, DELTA-2","Rattus norvegicus",5,"ASP A  38;VAL A   7;TYR A  48;SER A  41;THR A   9","None;None; CL A 305 (-4.0A);None;None","1.14A","4mm6A-5cc2A:undetectable","4mm6A-5cc2A:17.41"]]