SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cck'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y03_A_5FWA601_1 (BETA-1 ADRENERGIC RECEPTOR)	5cck	ANTIBODY 3BC315 FAB HEAVY CHAIN (Homo sapiens)	5 / 12	VAL H 163 VAL H 182 SER H 180 ASN H 197 ASN H 155	None	1.39A	2y03A-5cckH: undetectable	2y03A-5cckH: 21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y03_B_5FWB601_1 (BETA-1 ADRENERGIC RECEPTOR)	5cck	ANTIBODY 3BC315 FAB HEAVY CHAIN (Homo sapiens)	5 / 12	VAL H 163 VAL H 182 SER H 180 ASN H 197 ASN H 155	None	1.42A	2y03B-5cckH: undetectable	2y03B-5cckH: 21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NYA_A_JTZA1203_1 (BETA-2 ADRENERGIC RECEPTOR, LYSOZYME)	5cck	ANTIBODY 3BC315 FAB HEAVY CHAIN (Homo sapiens)	5 / 12	VAL H 163 VAL H 182 SER H 180 ASN H 197 ASN H 155	None	1.40A	3nyaA-5cckH: undetectable	3nyaA-5cckH: 18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LDO_A_ALEA1402_1 (LYSOZYME, BETA-2 ADRENERGIC RECEPTOR)	5cck	ANTIBODY 3BC315 FAB HEAVY CHAIN (Homo sapiens)	5 / 10	VAL H 163 VAL H 182 SER H 180 ASN H 197 ASN H 155	None	1.46A	4ldoA-5cckH: undetectable	4ldoA-5cckH: 19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6H7M_B_68HB405_0 (BETA-1 ADRENERGIC RECEPTOR)	5cck	ANTIBODY 3BC315 FAB HEAVY CHAIN (Homo sapiens)	5 / 12	VAL H 163 VAL H 182 SER H 180 ASN H 197 ASN H 155	None	1.41A	6h7mB-5cckH: undetectable	6h7mB-5cckH: 17.27

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2Y03_A_5FWA601_1","BETA-1 ADRENERGIC RECEPTOR","5cck","ANTIBODY 3BC315 FAB HEAVY CHAIN","Homo sapiens",5,"VAL H 163;VAL H 182;SER H 180;ASN H 197;ASN H 155","None","1.39A","2y03A-5cckH:undetectable","2y03A-5cckH:21.71"],["2Y03_B_5FWB601_1","BETA-1 ADRENERGIC RECEPTOR","5cck","ANTIBODY 3BC315 FAB HEAVY CHAIN","Homo sapiens",5,"VAL H 163;VAL H 182;SER H 180;ASN H 197;ASN H 155","None","1.42A","2y03B-5cckH:undetectable","2y03B-5cckH:21.71"],["3NYA_A_JTZA1203_1","BETA-2 ADRENERGIC RECEPTOR, LYSOZYME","5cck","ANTIBODY 3BC315 FAB HEAVY CHAIN","Homo sapiens",5,"VAL H 163;VAL H 182;SER H 180;ASN H 197;ASN H 155","None","1.40A","3nyaA-5cckH:undetectable","3nyaA-5cckH:18.60"],["4LDO_A_ALEA1402_1","LYSOZYME, BETA-2 ADRENERGIC RECEPTOR","5cck","ANTIBODY 3BC315 FAB HEAVY CHAIN","Homo sapiens",5,"VAL H 163;VAL H 182;SER H 180;ASN H 197;ASN H 155","None","1.46A","4ldoA-5cckH:undetectable","4ldoA-5cckH:19.82"],["6H7M_B_68HB405_0","BETA-1 ADRENERGIC RECEPTOR","5cck","ANTIBODY 3BC315 FAB HEAVY CHAIN","Homo sapiens",5,"VAL H 163;VAL H 182;SER H 180;ASN H 197;ASN H 155","None","1.41A","6h7mB-5cckH:undetectable","6h7mB-5cckH:17.27"]]