SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cct'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5cct DUTPASE
(Staphylococcus
virus
80alpha) 		4 / 7 GLY A  89
ALA A 136
THR A  47
ILE A  90
 DUP  A 201 (-4.0A)
None
None
None
 0.79A 1gtnA-5cctA:
undetectable
1gtnK-5cctA:
undetectable		 1gtnA-5cctA:
18.90
1gtnK-5cctA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5cct DUTPASE
(Staphylococcus
virus
80alpha) 		4 / 8 GLY A  89
ALA A 136
THR A  47
ILE A  90
 DUP  A 201 (-4.0A)
None
None
None
 0.83A 1gtnE-5cctA:
undetectable
1gtnF-5cctA:
undetectable		 1gtnE-5cctA:
18.90
1gtnF-5cctA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_1
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 5cct DUTPASE
(Staphylococcus
virus
80alpha) 		3 / 3 ARG A 134
ARG A  64
ILE A 129
 None
 0.77A 1uobA-5cctA:
undetectable		 1uobA-5cctA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_I_TRPI81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5cct DUTPASE
(Staphylococcus
virus
80alpha) 		4 / 8 GLY A  89
ALA A 136
THR A  47
ILE A  90
 DUP  A 201 (-4.0A)
None
None
None
 0.80A 1utdI-5cctA:
undetectable
1utdJ-5cctA:
undetectable		 1utdI-5cctA:
18.90
1utdJ-5cctA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		 5cct DUTPASE
(Staphylococcus
virus
80alpha) 		5 / 10 TYR A  27
ILE A 140
MET A  16
LEU A  88
VAL A  49
 None
 1.26A 2w98A-5cctA:
undetectable		 2w98A-5cctA:
21.49