SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cd2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_C_EAAC223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 5cd2 ENDO-1,4-D-GLUCANASE
(Aliivibrio
fischeri) 		4 / 8 LEU A 208
VAL A 383
MET A 275
PHE A  83
 None
 0.98A 1gsfC-5cd2A:
undetectable		 1gsfC-5cd2A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_1
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN))		 5cd2 ENDO-1,4-D-GLUCANASE
(Aliivibrio
fischeri) 		4 / 6 LEU A 271
PHE A 366
TYR A 143
VAL A 362
 None
 1.20A 1ibgH-5cd2A:
undetectable		 1ibgH-5cd2A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5cd2 ENDO-1,4-D-GLUCANASE
(Aliivibrio
fischeri) 		5 / 12 ILE A 346
VAL A 320
ALA A 266
GLY A 302
TYR A 342
 None
 0.95A 1kiaA-5cd2A:
undetectable		 1kiaA-5cd2A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5cd2 ENDO-1,4-D-GLUCANASE
(Aliivibrio
fischeri) 		5 / 12 ILE A 346
VAL A 320
ALA A 266
GLY A 302
TYR A 342
 None
 0.97A 1kiaB-5cd2A:
undetectable		 1kiaB-5cd2A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5cd2 ENDO-1,4-D-GLUCANASE
(Aliivibrio
fischeri) 		5 / 12 ILE A 346
VAL A 320
ALA A 266
GLY A 302
TYR A 342
 None
 0.96A 1kiaC-5cd2A:
undetectable		 1kiaC-5cd2A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5cd2 ENDO-1,4-D-GLUCANASE
(Aliivibrio
fischeri) 		5 / 12 ILE A 346
VAL A 320
ALA A 266
GLY A 302
TYR A 342
 None
 0.96A 1nbhB-5cd2A:
undetectable		 1nbhB-5cd2A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)		 5cd2 ENDO-1,4-D-GLUCANASE
(Aliivibrio
fischeri) 		4 / 8 TYR A 203
ASP A 136
TYR A  79
TYR A 359
 None
GOL  A 402 (-2.9A)
None
None
 1.35A 2bteA-5cd2A:
undetectable		 2bteA-5cd2A:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_A_LEUA1301_0
(LEUCYL-TRNA
SYNTHETASE)		 5cd2 ENDO-1,4-D-GLUCANASE
(Aliivibrio
fischeri) 		4 / 7 TYR A 203
ASP A 136
TYR A  79
TYR A 359
 None
GOL  A 402 (-2.9A)
None
None
 1.32A 2bytA-5cd2A:
undetectable		 2bytA-5cd2A:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_D_LEUD1601_0
(LEUCYL-TRNA
SYNTHETASE)		 5cd2 ENDO-1,4-D-GLUCANASE
(Aliivibrio
fischeri) 		4 / 7 TYR A 203
ASP A 136
TYR A  79
TYR A 359
 None
GOL  A 402 (-2.9A)
None
None
 1.32A 2bytD-5cd2A:
0.9		 2bytD-5cd2A:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COI_A_GBNA420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 5cd2 ENDO-1,4-D-GLUCANASE
(Aliivibrio
fischeri) 		5 / 10 TYR A 203
ARG A 268
THR A  73
ALA A 134
TYR A  79
 None
GOL  A 402 ( 4.9A)
GOL  A 402 ( 4.5A)
GOL  A 402 (-3.4A)
None
 1.48A 2coiA-5cd2A:
undetectable
2coiB-5cd2A:
undetectable		 2coiA-5cd2A:
22.09
2coiB-5cd2A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COI_B_GBNB420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 5cd2 ENDO-1,4-D-GLUCANASE
(Aliivibrio
fischeri) 		5 / 10 TYR A  79
TYR A 203
ARG A 268
THR A  73
ALA A 134
 None
None
GOL  A 402 ( 4.9A)
GOL  A 402 ( 4.5A)
GOL  A 402 (-3.4A)
 1.46A 2coiA-5cd2A:
undetectable
2coiB-5cd2A:
undetectable		 2coiA-5cd2A:
22.09
2coiB-5cd2A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_A_LEUA1887_0
(AMINOACYL-TRNA
SYNTHETASE)		 5cd2 ENDO-1,4-D-GLUCANASE
(Aliivibrio
fischeri) 		4 / 8 TYR A 203
ASP A 136
TYR A  79
TYR A 359
 None
GOL  A 402 (-2.9A)
None
None
 1.39A 2v0gA-5cd2A:
undetectable		 2v0gA-5cd2A:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_D_LEUD1883_0
(AMINOACYL-TRNA
SYNTHETASE)		 5cd2 ENDO-1,4-D-GLUCANASE
(Aliivibrio
fischeri) 		4 / 5 TYR A 203
ASP A 136
TYR A  79
TYR A 359
 None
GOL  A 402 (-2.9A)
None
None
 1.30A 2v0gD-5cd2A:
2.1		 2v0gD-5cd2A:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWM_A_SAMA301_0
(CATECHOL
O-METHYLTRANSFERASE)		 5cd2 ENDO-1,4-D-GLUCANASE
(Aliivibrio
fischeri) 		5 / 12 ASN A 154
GLY A 161
TYR A 156
SER A 166
HIS A 162
 None
 1.35A 3bwmA-5cd2A:
undetectable		 3bwmA-5cd2A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID802_0
(GLUTAMATE RECEPTOR 2)		 5cd2 ENDO-1,4-D-GLUCANASE
(Aliivibrio
fischeri) 		3 / 3 SER A  74
ASP A 136
ASN A 200
 None
GOL  A 402 (-2.9A)
None
 0.98A 3lslA-5cd2A:
undetectable
3lslD-5cd2A:
undetectable		 3lslA-5cd2A:
22.02
3lslD-5cd2A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_A_SAMA258_0
(PUTATIVE
METHYLTRANSFERASE)		 5cd2 ENDO-1,4-D-GLUCANASE
(Aliivibrio
fischeri) 		5 / 12 GLN A 372
GLY A 367
GLY A 369
GLN A  48
ALA A 324
 None
 1.20A 3sxjA-5cd2A:
undetectable		 3sxjA-5cd2A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_B_SAMB258_0
(PUTATIVE
METHYLTRANSFERASE)		 5cd2 ENDO-1,4-D-GLUCANASE
(Aliivibrio
fischeri) 		5 / 12 GLN A 372
GLY A 367
GLY A 369
GLN A  48
ALA A 324
 None
 1.20A 3sxjB-5cd2A:
undetectable		 3sxjB-5cd2A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_B_SAMB300_0
(PUTATIVE
METHYLTRANSFERASE)		 5cd2 ENDO-1,4-D-GLUCANASE
(Aliivibrio
fischeri) 		5 / 12 GLN A 372
GLY A 367
GLY A 369
GLN A  48
ALA A 324
 None
 1.16A 3t7sB-5cd2A:
undetectable		 3t7sB-5cd2A:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_D_SAMD300_0
(PUTATIVE
METHYLTRANSFERASE)		 5cd2 ENDO-1,4-D-GLUCANASE
(Aliivibrio
fischeri) 		5 / 12 GLN A 372
GLY A 367
GLY A 369
GLN A  48
ALA A 324
 None
 1.18A 3t7sD-5cd2A:
undetectable		 3t7sD-5cd2A:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR5_A_SRYA1860_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S12)		 5cd2 ENDO-1,4-D-GLUCANASE
(Aliivibrio
fischeri) 		3 / 3 LYS A 238
PRO A 292
LYS A 313
 None
 1.49A 4dr5L-5cd2A:
undetectable		 4dr5L-5cd2A:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR6_A_SRYA1956_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S12)		 5cd2 ENDO-1,4-D-GLUCANASE
(Aliivibrio
fischeri) 		3 / 3 LYS A 238
PRO A 292
LYS A 313
 None
 1.48A 4dr6L-5cd2A:
undetectable		 4dr6L-5cd2A:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUZ_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 5cd2 ENDO-1,4-D-GLUCANASE
(Aliivibrio
fischeri) 		3 / 3 LYS A 238
PRO A 292
LYS A 313
 None
 1.48A 4duzL-5cd2A:
undetectable		 4duzL-5cd2A:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV7_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 5cd2 ENDO-1,4-D-GLUCANASE
(Aliivibrio
fischeri) 		3 / 3 LYS A 238
PRO A 292
LYS A 313
 None
 1.28A 4dv7L-5cd2A:
undetectable		 4dv7L-5cd2A:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_1
(SEPIAPTERIN
REDUCTASE)		 5cd2 ENDO-1,4-D-GLUCANASE
(Aliivibrio
fischeri) 		5 / 12 PHE A  52
TRP A  49
ALA A  84
GLY A  60
LEU A  96
 None
 1.19A 4j7xB-5cd2A:
undetectable		 4j7xB-5cd2A:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U14_A_0HKA2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 5cd2 ENDO-1,4-D-GLUCANASE
(Aliivibrio
fischeri) 		4 / 4 ASN A 360
LEU A 271
PHE A  52
TYR A  79
 None
 1.45A 4u14A-5cd2A:
0.0		 4u14A-5cd2A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_A_ADNA303_1
(5'/3'-NUCLEOTIDASE
SURE)		 5cd2 ENDO-1,4-D-GLUCANASE
(Aliivibrio
fischeri) 		5 / 10 GLY A 161
ALA A 105
ILE A 141
LEU A 164
LEU A 145
 None
 1.15A 4xj7A-5cd2A:
undetectable
4xj7B-5cd2A:
undetectable		 4xj7A-5cd2A:
21.11
4xj7B-5cd2A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_D_ADND303_1
(5'/3'-NUCLEOTIDASE
SURE)		 5cd2 ENDO-1,4-D-GLUCANASE
(Aliivibrio
fischeri) 		5 / 10 LEU A 164
LEU A 145
GLY A 161
ALA A 105
ILE A 141
 None
 1.16A 4xj7C-5cd2A:
undetectable
4xj7D-5cd2A:
undetectable		 4xj7C-5cd2A:
21.11
4xj7D-5cd2A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_A_SAMA1001_1
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 5cd2 ENDO-1,4-D-GLUCANASE
(Aliivibrio
fischeri) 		4 / 4 SER A  78
SER A  74
GLU A 172
ASP A 136
 None
None
None
GOL  A 402 (-2.9A)
 1.47A 4ymgA-5cd2A:
undetectable		 4ymgA-5cd2A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7F_A_SAMA301_0
(PUTATIVE
O-METHYLTRANSFERASE
RV1220C)		 5cd2 ENDO-1,4-D-GLUCANASE
(Aliivibrio
fischeri) 		5 / 12 GLY A 302
GLY A 321
GLY A 319
GLN A  48
ALA A 324
 None
 1.17A 5x7fA-5cd2A:
undetectable		 5x7fA-5cd2A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7F_A_SAMA301_0
(PUTATIVE
O-METHYLTRANSFERASE
RV1220C)		 5cd2 ENDO-1,4-D-GLUCANASE
(Aliivibrio
fischeri) 		5 / 12 GLY A 302
GLY A 321
GLY A 319
GLU A 349
ALA A 324
 None
 0.86A 5x7fA-5cd2A:
undetectable		 5x7fA-5cd2A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_D_ADND502_2
(-)		 5cd2 ENDO-1,4-D-GLUCANASE
(Aliivibrio
fischeri) 		4 / 5 ILE A  71
GLN A  77
THR A  73
THR A 120
 None
None
GOL  A 402 ( 4.5A)
None
 1.12A 6f3mD-5cd2A:
undetectable		 6f3mD-5cd2A:
23.11