SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cd3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA302_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5cd3 DRVIA7 HEAVY CHAIN
(Homo
sapiens) 		4 / 6 LEU G 188
GLY G 189
ALA G 124
PRO G 125
 None
 0.52A 3huoA-5cd3G:
undetectable		 3huoA-5cd3G:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5cd3 DRVIA7 HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER G 187
GLY G 133
THR G 134
ALA G 135
THR G 130
 None
 0.90A 4qvyH-5cd3G:
undetectable		 4qvyH-5cd3G:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5cd3 DRVIA7 HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER G 187
GLY G 133
THR G 134
ALA G 135
THR G 130
 None
 0.90A 4qvyV-5cd3G:
undetectable
4qvyW-5cd3G:
undetectable		 4qvyV-5cd3G:
19.68
4qvyW-5cd3G:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5cd3 DRVIA7 HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER G 187
GLY G 133
THR G 134
ALA G 135
THR G 130
 None
 0.88A 5bxnH-5cd3G:
undetectable
5bxnI-5cd3G:
undetectable		 5bxnH-5cd3G:
19.26
5bxnI-5cd3G:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5cd3 DRVIA7 HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER G 187
GLY G 133
THR G 134
ALA G 135
THR G 130
 None
 0.88A 5d0xV-5cd3G:
undetectable		 5d0xV-5cd3G:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5cd3 DRVIA7 HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER G 187
GLY G 133
THR G 134
ALA G 135
THR G 130
 None
 0.85A 5l5fH-5cd3G:
undetectable
5l5fI-5cd3G:
undetectable		 5l5fH-5cd3G:
19.68
5l5fI-5cd3G:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5cd3 DRVIA7 HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER G 187
GLY G 133
THR G 134
ALA G 135
THR G 130
 None
 0.85A 5l5fV-5cd3G:
undetectable
5l5fW-5cd3G:
undetectable		 5l5fV-5cd3G:
19.68
5l5fW-5cd3G:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBF_A_ACTA507_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 5cd3 DRVIA7 HEAVY CHAIN
(Homo
sapiens) 		3 / 3 LYS G  98
SER G  32
SER G  31
 None
 1.06A 6gbfA-5cd3G:
undetectable		 6gbfA-5cd3G:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_H_BO2H301_0
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5cd3 DRVIA7 HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER G 187
GLY G 133
THR G 134
ALA G 135
THR G 130
 None
 0.96A 6hwdH-5cd3G:
undetectable
6hwdI-5cd3G:
undetectable		 6hwdH-5cd3G:
19.53
6hwdI-5cd3G:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_V_BO2V301_0
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5cd3 DRVIA7 HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER G 187
GLY G 133
THR G 134
ALA G 135
THR G 130
 None
 0.96A 6hwdV-5cd3G:
undetectable		 6hwdV-5cd3G:
19.53