SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cd6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXH_B_PACB1001_0
(PENICILLIN ACYLASE)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		4 / 7 PHE A 263
SER A 205
ALA A 207
ILE A 130
 None
 0.93A 1fxhA-5cd6A:
undetectable
1fxhB-5cd6A:
undetectable		 1fxhA-5cd6A:
16.81
1fxhB-5cd6A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JQD_A_HSMA600_1
(HISTAMINE
N-METHYLTRANSFERASE)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		4 / 7 GLU A 337
GLN A 187
VAL A 132
TRP A 172
 None
 1.03A 1jqdA-5cd6A:
undetectable		 1jqdA-5cd6A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA996_1
(GLUCOAMYLASE GLU1)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		4 / 7 ASP A 214
THR A 342
GLY A 273
TYR A 266
 None
 0.94A 2f6dA-5cd6A:
undetectable		 2f6dA-5cd6A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_D_CHDD702_0
(FERROCHELATASE)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		3 / 3 ARG A 440
GLY A 195
PRO A 194
 None
 0.75A 2hreD-5cd6A:
undetectable		 2hreD-5cd6A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_0
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		5 / 12 GLY A 439
PRO A 404
GLY A 406
ALA A 438
LEU A 465
 None
 0.98A 2plwA-5cd6A:
undetectable		 2plwA-5cd6A:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_D_BEZD1221_0
(PEROXIREDOXIN 6)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		4 / 7 THR A 267
PRO A 268
SER A 269
GLU A 244
 None
 1.06A 2v2gC-5cd6A:
undetectable
2v2gD-5cd6A:
undetectable		 2v2gC-5cd6A:
17.85
2v2gD-5cd6A:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		3 / 3 GLU A 163
GLU A 165
TRP A 369
 None
 1.33A 3hrdA-5cd6A:
undetectable
3hrdE-5cd6A:
undetectable
3hrdF-5cd6A:
undetectable		 3hrdA-5cd6A:
20.50
3hrdE-5cd6A:
20.50
3hrdF-5cd6A:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		4 / 4 GLY A 273
TYR A 275
GLY A 264
ASP A 218
 None
 0.98A 3kl3A-5cd6A:
undetectable		 3kl3A-5cd6A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_B_D16B520_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		5 / 12 THR A 478
ILE A 482
PRO A 483
SER A 486
THR A 435
 None
 1.21A 3nrrB-5cd6A:
undetectable		 3nrrB-5cd6A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3N_A_DLUA398_1
(PFV INTEGRASE)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		4 / 8 GLY A 195
PRO A 200
GLU A 326
ARG A 440
 None
 0.82A 3s3nA-5cd6A:
undetectable		 3s3nA-5cd6A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_A_NCAA1163_0
(TANKYRASE-2)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		4 / 8 GLY A 292
SER A 290
TYR A 291
GLU A 312
 None
None
None
GOL  A 703 (-2.8A)
 0.87A 3u9hA-5cd6A:
undetectable		 3u9hA-5cd6A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_B_NCAB1164_0
(TANKYRASE-2)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		4 / 8 GLY A 292
SER A 290
TYR A 291
GLU A 312
 None
None
None
GOL  A 703 (-2.8A)
 0.85A 3u9hB-5cd6A:
undetectable		 3u9hB-5cd6A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		4 / 6 THR A  43
ARG A 563
ILE A 496
LEU A  46
 None
 1.19A 4acaC-5cd6A:
undetectable		 4acaC-5cd6A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BJC_A_RPBA2162_1
(TANKYRASE-2)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		4 / 8 GLY A 292
SER A 290
TYR A 291
GLU A 312
 None
None
None
GOL  A 703 (-2.8A)
 0.88A 4bjcA-5cd6A:
undetectable		 4bjcA-5cd6A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		3 / 3 TYR A  61
ARG A 122
SER A  60
 None
 0.98A 4dr2I-5cd6A:
undetectable
4dr2J-5cd6A:
undetectable		 4dr2I-5cd6A:
12.48
4dr2J-5cd6A:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		4 / 6 ALA A 417
ALA A 394
PRO A 395
LEU A 381
 None
 0.85A 4dtzA-5cd6A:
undetectable		 4dtzA-5cd6A:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_B_MOAB502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		4 / 8 SER A 166
GLY A  54
THR A  48
GLY A 439
 None
 0.78A 4fo4B-5cd6A:
undetectable		 4fo4B-5cd6A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JUO_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		3 / 4 SER A 486
GLY A  44
GLU A  63
 None
 0.59A 4juoA-5cd6A:
undetectable
4juoC-5cd6A:
undetectable		 4juoA-5cd6A:
20.80
4juoC-5cd6A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA505_0
(RNA POLYMERASE
3D-POL)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		3 / 3 CYH A  92
ASN A 143
LYS A  94
 None
 0.88A 4k50A-5cd6A:
1.7		 4k50A-5cd6A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF7_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		3 / 3 TYR A  61
ARG A 122
SER A  60
 None
 1.08A 4lf7I-5cd6A:
undetectable
4lf7J-5cd6A:
undetectable		 4lf7I-5cd6A:
12.48
4lf7J-5cd6A:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF8_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		3 / 3 TYR A  61
ARG A 122
SER A  60
 None
 1.08A 4lf8I-5cd6A:
undetectable
4lf8J-5cd6A:
undetectable		 4lf8I-5cd6A:
12.48
4lf8J-5cd6A:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_ACTA605_0
(SERUM ALBUMIN)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		4 / 6 TYR A 116
GLU A 144
ARG A 122
ASN A 143
 None
 1.39A 4zbqA-5cd6A:
undetectable		 4zbqA-5cd6A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CU6_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		4 / 6 TYR A 349
ILE A 277
VAL A 260
ALA A 262
 None
 0.91A 5cu6A-5cd6A:
undetectable		 5cu6A-5cd6A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQY_A_BEZA401_0
(THIOREDOXIN)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		4 / 8 ILE A 277
VAL A 353
SER A 281
GLU A 280
 None
 0.93A 5dqyA-5cd6A:
undetectable		 5dqyA-5cd6A:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB601_0
(THIOCYANATE
DEHYDROGENASE)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		3 / 3 HIS A 344
ASP A 343
HIS A 100
 None
 0.72A 5oexB-5cd6A:
1.7		 5oexB-5cd6A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC601_0
(THIOCYANATE
DEHYDROGENASE)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		3 / 3 HIS A 344
ASP A 343
HIS A 100
 None
 0.75A 5oexC-5cd6A:
undetectable		 5oexC-5cd6A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD601_0
(THIOCYANATE
DEHYDROGENASE)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		3 / 3 HIS A 344
ASP A 343
HIS A 100
 None
 0.74A 5oexD-5cd6A:
undetectable		 5oexD-5cd6A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		4 / 8 TRP A 299
THR A 560
TYR A 561
THR A 564
 None
 1.16A 5tzoA-5cd6A:
undetectable		 5tzoA-5cd6A:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		4 / 8 TRP A 299
THR A 560
TYR A 561
THR A 564
 None
 1.13A 5tzoB-5cd6A:
undetectable		 5tzoB-5cd6A:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		4 / 8 TRP A 299
THR A 560
TYR A 561
THR A 564
 None
 1.19A 5tzoC-5cd6A:
undetectable		 5tzoC-5cd6A:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1802_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		4 / 7 PHE A 134
VAL A 189
PRO A 317
ILE A 318
 None
 1.09A 5vkqA-5cd6A:
undetectable
5vkqB-5cd6A:
undetectable		 5vkqA-5cd6A:
15.61
5vkqB-5cd6A:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		4 / 8 PHE A 134
VAL A 189
PRO A 317
ILE A 318
 None
 1.08A 5vkqB-5cd6A:
undetectable
5vkqC-5cd6A:
undetectable		 5vkqB-5cd6A:
15.61
5vkqC-5cd6A:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		4 / 7 PHE A 134
VAL A 189
PRO A 317
ILE A 318
 None
 1.09A 5vkqC-5cd6A:
undetectable
5vkqD-5cd6A:
undetectable		 5vkqC-5cd6A:
15.61
5vkqD-5cd6A:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 5cd6 TPR-DOMAIN
CONTAINING PROTEIN
(Parabacteroides
distasonis) 		4 / 6 LEU A 488
TYR A 428
ASP A 399
GLU A 398
 None
 1.41A 6djzC-5cd6A:
1.0		 6djzC-5cd6A:
17.82