SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5cd7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 5cd7 MATERNAL EFFECT
PROTEIN OSKAR
(Drosophila
melanogaster) 		5 / 12 PHE A 189
ASN A 187
VAL A 160
LEU A 191
PHE A 198
 None
 1.18A 2zzmA-5cd7A:
undetectable		 2zzmA-5cd7A:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_0
(MODIFICATION
METHYLASE HHAI)		 5cd7 MATERNAL EFFECT
PROTEIN OSKAR
(Drosophila
melanogaster) 		5 / 12 PHE A 189
ASP A 157
PRO A 190
LEU A 191
ASN A 187
 None
 1.17A 3eeoA-5cd7A:
undetectable		 3eeoA-5cd7A:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 5cd7 MATERNAL EFFECT
PROTEIN OSKAR
(Drosophila
melanogaster) 		4 / 5 ILE A 156
ILE A 177
TYR A 181
GLU A 180
 None
None
None
GOL  A 302 (-3.5A)
 1.02A 4a99D-5cd7A:
undetectable		 4a99D-5cd7A:
13.11